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Antifungals and Drug Resistance

open access: yesEncyclopedia, 2022
Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal).
Chowdhury Mobaswar Hossain   +6 more
doaj   +2 more sources

Antifungal resistance in dermatology

open access: yesIndian Journal of Dermatology, 2018
Cutaneous fungal infections affect more than one-fourth of world's population. The pathogenesis and severity of fungal infection depend on various immunological and nonimmunological factors.
Varadraj Pai   +2 more
doaj   +2 more sources

Efflux-mediated antifungal drug resistance [PDF]

open access: yesClinical Microbiology Reviews, 2009
Fungi cause serious infections in the immunocompromised and debilitated, and the incidence of invasive mycoses has increased significantly over the last 3 decades.
Cannon, Richard D.   +9 more
core   +3 more sources

Antifungal drug resistance in Candida species

open access: yesJournal of Global Antimicrobial Resistance, 2014
Invasive Candida infections are well established infectious entities of immunocompromised or critically ill patients and are characterised by high morbidity and mortality.
G. Morace, F. Perdoni, E. Borghi
core   +4 more sources

Cryptococcus flips its lid – membrane phospholipid asymmetry modulates antifungal drug resistance and virulence

open access: yesMicrobial Cell, 2016
Human fungal infections are increasing in prevalence and acquisition of antifungal drug resistance, while our antifungal drug armamentarium remains very limited, constituting a significant public health problem. Despite the fact that prominent antifungal
Erika Shor   +3 more
doaj   +2 more sources

Antifungal Drug Resistance - Concerns for Veterinarians [PDF]

open access: yesVeterinary World, 2009
In the 1990s, there were increased incidences of fungal infectious diseases in human population which might be due to increase in immunosuppressive diseases.
Bharat B. Bhanderi   +1 more
doaj   +1 more source

Antifungal drug resistance: an update. [PDF]

open access: yesEur J Hosp Pharm, 2022
The number of antifungal classes is small, and resistance is becoming a much more frequent problem. Much greater emphasis needs to be placed on susceptibility testing and antifungal stewardship. Such efforts demonstrably improve survival and overall clinical outcomes.
Denning DW.
europepmc   +5 more sources

Antifungal resistance in dermatophytosis: A global health concern

open access: yesLetters in Animal Biology, 2022
Dermatophytosis is a common dermatological problem in animals as well as humans which is associated with interference in immune function. Unlike the antibacterial resistance which is frequently reported, antifungal resistance is less commonly reported ...
Jubeda Begum, P Das
doaj   +1 more source

Potential Strategies to Control the Risk of Antifungal Resistance in Humans: A Comprehensive Review

open access: yesAntibiotics, 2023
Fungal infections are becoming one of the main causes of morbidity and mortality in people with weakened immune systems. Mycoses are becoming more common, despite greater knowledge and better treatment methods, due to the regular emergence of resistance ...
Ali A. Rabaan   +19 more
doaj   +1 more source

Molecular mechanisms governing antifungal drug resistance. [PDF]

open access: yesNPJ Antimicrob Resist, 2023
AbstractFungal pathogens are a severe public health problem. The leading causative agents of systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus genera. As opportunistic pathogens, these fungi are generally harmless in healthy hosts; however, they can cause significant morbidity and mortality in immunocompromised ...
Lee Y, Robbins N, Cowen LE.
europepmc   +3 more sources

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