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Fungal Drug Response and Antimicrobial Resistance
Antifungal resistance is a growing concern as it poses a significant threat to public health. Fungal infections are a significant cause of morbidity and mortality, especially in immunocompromised individuals.
Amparo Pascual-Ahuir +5 more
core +2 more sources
Antifungal drug resistance in Candida species
Invasive Candida infections are well established infectious entities of immunocompromised or critically ill patients and are characterised by high morbidity and mortality. Owing to the common eukaryotic structure of fungi and humans, a limited number of antifungal drugs is available for therapeutic purposes.
G. Morace, F. Perdoni, E. Borghi
openaire +4 more sources
Antifungal resistance in dermatology
Cutaneous fungal infections affect more than one-fourth of world's population. The pathogenesis and severity of fungal infection depend on various immunological and nonimmunological factors.
Varadraj Pai +2 more
core +2 more sources
MARDy: Mycology Antifungal Resistance Database [PDF]
Summary: The increase of antifungal drug resistance is a major global human health concern and threatens agriculture and food security; in order to tackle these concerns, it is important to understand the mechanisms that cause antifungal resistance.
A Abdolrasouli (21905603) +6 more
core +8 more sources
Antifungal Drug Resistance - Concerns for Veterinarians [PDF]
In the 1990s, there were increased incidences of fungal infectious diseases in human population which might be due to increase in immunosuppressive diseases.
Mahendra Mohan Yadav and Ashish Roy +1 more
core +1 more source
Antifungal resistance in dermatophytosis: A global health concern
Dermatophytosis is a common dermatological problem in animals as well as humans which is associated with interference in immune function. Unlike the antibacterial resistance which is frequently reported, antifungal resistance is less commonly reported ...
Jubeda Begum, P Das
doaj +1 more source
Potential Strategies to Control the Risk of Antifungal Resistance in Humans: A Comprehensive Review
Fungal infections are becoming one of the main causes of morbidity and mortality in people with weakened immune systems. Mycoses are becoming more common, despite greater knowledge and better treatment methods, due to the regular emergence of resistance ...
Ali A. Rabaan +19 more
doaj +1 more source
RNAi epimutations conferring antifungal drug resistance are inheritable. [PDF]
Epimutations modify gene expression and lead to phenotypic variation while the encoding DNA sequence remains unchanged. Epimutations mediated by RNA interference (RNAi) and/or chromatin modifications can confer antifungal drug resistance and may impact ...
Pérez-Arques C +4 more
europepmc +2 more sources
Molecular Mechanisms of Antifungal Drug Resistance in Candida Species [PDF]
Invasive Candidal infections have emerged as one of the major threats to the world. Although, many new antifungal drugs have been developed in the recent years, the emergence of drug resistance has become a major deterrent in the antifungal therapy ...
Lakshmi Krishnasamy +3 more
doaj +1 more source
Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Aspergillus Fungi
Certain Aspergillus fungi cause aspergillosis, a set of diseases that typically affect immunocompromised individuals. Most cases of aspergillosis are caused by Aspergillus fumigatus, which infects millions of people annually.
Renato Augusto Corrêa dos Santos +7 more
doaj +1 more source

