Results 21 to 30 of about 2,517,016 (285)

Genome architecture drives antifungal resistance in Candida auris [PDF]

open access: yesNature Communications
Antifungal resistance often results from mutations in drug target genes. However, Narayanan et al. show that segmental duplication and supernumerary chromosomes also contribute to resistance in the emerging fungal pathogen Candida auris. The work expands
Anuradha Chowdhary   +2 more
doaj   +2 more sources

Antifungal Resistance in Cryptococcal Infections

open access: yesPathogens
Antifungal therapy, especially with the azoles, could promote the incidence of less susceptible isolates of Cryptococcus neoformans and C. gattii species complexes (SC), mostly in developing countries.
Lucas X. Bonfietti   +10 more
core   +4 more sources

MARDy: Mycology Antifungal Resistance Database

open access: yes, 2018
Summary: The increase of antifungal drug resistance is a major global human health concern and threatens agriculture and food security; in order to tackle these concerns, it is important to understand the mechanisms that cause antifungal resistance.
A Abdolrasouli (21905603)   +6 more
core   +7 more sources

Fungal Drug Response and Antimicrobial Resistance

open access: yesJournal of Fungi, 2023
Antifungal resistance is a growing concern as it poses a significant threat to public health. Fungal infections are a significant cause of morbidity and mortality, especially in immunocompromised individuals.
Paloma Osset-Trénor   +2 more
doaj   +1 more source

Antifungal resistance in dermatophytosis: A global health concern

open access: yesLetters in Animal Biology, 2022
Dermatophytosis is a common dermatological problem in animals as well as humans which is associated with interference in immune function. Unlike the antibacterial resistance which is frequently reported, antifungal resistance is less commonly reported ...
Jubeda Begum, P Das
doaj   +1 more source

Carbohydrate derived fulvic acid : an in vitro investigation of a novel membrane active antiseptic agent against Candida albicans biofilms [PDF]

open access: yes, 2012
Carbohydrate derived fulvic acid (CHD-FA) is a heat stable low molecular weight, water soluble, cationic, colloidal material with proposed therapeutic properties.
Murray, Colin   +7 more
core   +4 more sources

Antifungal Resistance on the Rise

open access: yesJournal of Investigative Dermatology, 2023
Comment on : Gupta AK, Cooper EA, Wang T, Polla Ravi S, Lincoln SA, Piguet V, McCarthy LR, Bakotic WL. Detection of Squalene Epoxidase Mutations in United States Patients with Onychomycosis: Implications for Management. J Invest Dermatol. 2023 Dec;143(12):2476-2483.e7. doi: 10.1016/j.jid.2023.04.032. Epub 2023 May 24. PMID: 37236595.
Monod, Michel   +2 more
openaire   +2 more sources

Antifungal resistance, combinations and pipeline: oh my!

open access: yesDrugs in Context, 2023
Invasive fungal infections are a strong contributor to healthcare costs, morbidity and mortality, especially amongst hospitalized patients. Historically, Candida was responsible for approximately 15% of all nosocomial bloodstream infections.
Kayla R Stover   +4 more
doaj   +1 more source

Antifungal resistance and clinical significance in small animals

open access: yesGerman Journal of Veterinary Research, 2022
Fungal diseases have risen in conjunction with the increasing number of immunosuppressive diseases in human and animal populations. Despite the introduction of new antifungal agents in recent years, the incidence of fungal infections continues to ...
Yasemin Kaya   +3 more
doaj   +1 more source

The Microevolution of Antifungal Drug Resistance in Pathogenic Fungi

open access: yesMicroorganisms, 2023
The mortality rates of invasive fungal infections remain high because of the limited number of antifungal drugs available and antifungal drug resistance, which can rapidly evolve during treatment.
Kylie J. Boyce
doaj   +1 more source

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