Results 41 to 50 of about 116,695 (299)

Update on Antifungal Drug Resistance [PDF]

Current Clinical Microbiology Reports, 2015
Invasive fungal infections remain a major source of global morbidity and mortality, especially among patients with underlying immune suppression. Successful patient management requires antifungal therapy. Yet, treatment choices are restricted due to limited classes of antifungal agents and the emergence of antifungal drug resistance.
David S, Perlin, Erika, Shor, Yanan, Zhao   +2 more
openaire   +2 more sources

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal. [PDF]

, 2013
Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice.
A. Loyse, Dromer, F, Day, J, Lortholary, O, O. Lortholary, Harrison, TS, F. Dromer, Day, Jeremy, T. S. Harrison, J. Day, Loyse, A   +10 more
core   +1 more source

Ellagic acid: an alternative for antifungal drugs resistance in HIV/AIDS patients with oropharyngeal candidiasis

HIV & AIDS Review. International Journal of HIV-Related Problems, 2020
Oropharyngeal candidiasis (OPC) is considered the most common fungal infection in human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. Antifungal drug, azole group, is the preferred treatment.
Satutya Wicaksono, Fianza Rezkita, Fadhilah N. Wijaya, Alexander P. Nugraha, Saka Winias   +4 more
doaj   +1 more source

Resistance to antifungals that target CYP51 [PDF]

Journal of Chemical Biology, 2014
Fungal diseases are an increasing global burden. Fungi are now recognised to kill more people annually than malaria, whilst in agriculture, fungi threaten crop yields and food security. Azole resistance, mediated by several mechanisms including point mutations in the target enzyme (CYP51), is increasing through selection pressure as a result of ...
Josie Parker, Andrew Warrilow, Claire Price, Jonathan Mullins, Diane Kelly, Steven Kelly   +5 more
openaire   +4 more sources

Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Aspergillus Fungi

Frontiers in Fungal Biology, 2021
Certain Aspergillus fungi cause aspergillosis, a set of diseases that typically affect immunocompromised individuals. Most cases of aspergillosis are caused by Aspergillus fumigatus, which infects millions of people annually.
Renato Augusto Corrêa dos Santos, Renato Augusto Corrêa dos Santos, Matthew E. Mead, Jacob L. Steenwyk, Olga Rivero-Menéndez, Ana Alastruey-Izquierdo, Gustavo Henrique Goldman, Antonis Rokas   +7 more
doaj   +1 more source

Chemical Composition of Essential Oilsof Thymus and Mentha Speciesand Their Antifungal Activities [PDF]

, 2009
The potential antifungal effects of Thymus vulgaris L., Thymus tosevii L., Mentha spicata L., and Mentha piperita L. (Labiatae) essential oils and their components against 17 micromycetal food poisoning, plant, animal and human pathogens are presented ...
Marin, P.D., Petar D. Marin, Vlatka Vajs, Dejan D. Brkić, Marin, Petar D, Jelena Vukojević, Vajs, V., Vajs, Vlatka E, van Griensven, L.J.L.D., Marin, Petar D., Brkić, Dejan, Marin, Petar, Brkić, Dejan D, Leo J. L. D. Van Griensven, Van Griensven, Leo J. L. D., Leo J. L. D. van Griensven, Vukojević, J, Brkić, D D, Griensven, L.J.L.D., van, Dejan D. Brkić, van Griensven, Leo JLD, Jelena Vukojević, Vukojević, Jelena B., Van Griensven, Leo J.L.D., Vukojevic,, J., Vajs, Vlatka, Sokovic,, M.D., Marina D. Soković, Marina D. Soković, Soković, Marina, Vukojević, Jelena, Brkic, D.D.   +31 more
core   +1 more source

Antifungals and Drug Resistance

Encyclopedia, 2022
Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal).
Chowdhury Mobaswar Hossain, Lisa Kathleen Ryan, Meeta Gera, Sabyasachi Choudhuri, Nazmun Lyle, Kazi Asraf Ali, Gill Diamond   +6 more
doaj   +1 more source

Mechanisms of Antifungal Drug Resistance [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
Antifungal therapy is a central component of patient management for acute and chronic mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal drug classes. Clinical management of fungal diseases is further compromised by the emergence of antifungal drug resistance, which eliminates available drug classes as treatment ...
Cowen Leah E, Sanglard Dominique, Howard Susan J, Rogers P David, Perlin David S   +4 more
openaire   +3 more sources

Carbohydrate derived fulvic acid: an in vitro investigation of a novel membrane active antiseptic agent against Candida albicans biofilms [PDF]

, 2012
Carbohydrate derived fulvic acid (CHD-FA) is a heat stable low molecular weight, water soluble, cationic, colloidal material with proposed therapeutic properties.
Brian Jones, Murray, Colin, Bagg, Jeremy, Craig eWilliams, Leighann eSherry, Jones, Brian, Owain Millington, Jose, Anto, Gordon eRamage, Millington, Owain, Leighann Sherry, Anto Jose, Jeremy Bagg, Sherry, Leighann, Colin eMurray, Ramage, Gordon, Colin Murray, Williams, Craig, Anto eJose, Owain eMillington, Brian eJones, Gordon Ramage, Jeremy eBagg, Craig Williams   +23 more
core   +1 more source

Candidiasis and Mechanisms of Antifungal Resistance [PDF]

Antibiotics, 2020
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common. These are pathogenic yeast and are usually present in the normal microbiome.
Somanon Bhattacharya, Sutthichai Sae-Tia, Bettina C. Fries   +2 more
openaire   +3 more sources