Results 31 to 40 of about 116,042 (299)
Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi [PDF]
, 2008 Background: In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.
Borelli, Claudia +10 more
core +1 more source
HIV & AIDS Review. International Journal of HIV-Related Problems, 2020 Oropharyngeal candidiasis (OPC) is considered the most common fungal infection in human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. Antifungal drug, azole group, is the preferred treatment.
Satutya Wicaksono +4 more
doaj +1 more source
Update on Antifungal Drug Resistance [PDF]
Current Clinical Microbiology Reports, 2015 Invasive fungal infections remain a major source of global morbidity and mortality, especially among patients with underlying immune suppression. Successful patient management requires antifungal therapy. Yet, treatment choices are restricted due to limited classes of antifungal agents and the emergence of antifungal drug resistance.
David S, Perlin +2 more
openaire +2 more sources
Resistance to antifungals that target CYP51 [PDF]
Journal of Chemical Biology, 2014 Fungal diseases are an increasing global burden. Fungi are now recognised to kill more people annually than malaria, whilst in agriculture, fungi threaten crop yields and food security. Azole resistance, mediated by several mechanisms including point mutations in the target enzyme (CYP51), is increasing through selection pressure as a result of ...
Josie Parker +5 more
openaire +4 more sources
Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Aspergillus Fungi
Frontiers in Fungal Biology, 2021 Certain Aspergillus fungi cause aspergillosis, a set of diseases that typically affect immunocompromised individuals. Most cases of aspergillosis are caused by Aspergillus fumigatus, which infects millions of people annually.
Renato Augusto Corrêa dos Santos +7 more
doaj +1 more source
Antifungals and Drug Resistance
Encyclopedia, 2022 Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal).
Chowdhury Mobaswar Hossain +6 more
doaj +1 more source
Chemical Composition of Essential Oilsof Thymus and Mentha Speciesand Their Antifungal Activities [PDF]
, 2009 The potential antifungal effects of Thymus vulgaris L., Thymus tosevii L., Mentha spicata L., and Mentha piperita L. (Labiatae) essential oils and their components against 17 micromycetal food poisoning, plant, animal and human pathogens are presented ...
Marin, P.D. +31 more
core +1 more source
The Quiet and Underappreciated Rise of Drug-Resistant Invasive Fungal Pathogens
Journal of Fungi, 2020 Human fungal pathogens are attributable to a significant economic burden and mortality worldwide. Antifungal treatments, although limited in number, play a pivotal role in decreasing mortality and morbidities posed by invasive fungal infections (IFIs ...
Amir Arastehfar +7 more
doaj +1 more source
Candidiasis and Mechanisms of Antifungal Resistance [PDF]
Antibiotics, 2020 Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common. These are pathogenic yeast and are usually present in the normal microbiome.
Somanon Bhattacharya +2 more
openaire +3 more sources
Molecular characterization of cellulose synthase (CesA) genes and impact of mutations on fungicide resistance in oomycetes [PDF]
, 2012 Many oomycetes are important pathogens of plants (e.g. arable crops, fruit and forest trees), animals or microbes and, upon attacking their hosts, cause considerable economic damage mainly in agriculture and aquaculture.
Blum, Mathias
core +1 more source