Results 31 to 40 of about 3,193,961 (325)
Molecular Mechanisms of Antifungal Drug Resistance in Candida Species [PDF]
Journal of Clinical and Diagnostic Research, 2018 Invasive Candidal infections have emerged as one of the major threats to the world. Although, many new antifungal drugs have been developed in the recent years, the emergence of drug resistance has become a major deterrent in the antifungal therapy ...
Lakshmi Krishnasamy +3 more
doaj +1 more source
Emerging Antifungal Resistance in Fungal Pathogens. [PDF]
Curr Clin Microbiol RepPurpose of Review Over recent decades, the number of outbreaks caused by fungi has increased for humans, plants (including important crop species) and animals.
Hui ST, Gifford H, Rhodes J.
europepmc +2 more sources
Candida parapsilosis sensu stricto Antifungal Resistance Mechanisms and Associated Epidemiology
Journal of Fungi, 2023 Fungal diseases cause millions of deaths per year worldwide. Antifungal resistance has become a matter of great concern in public health. In recent years rates of non-albicans species have risen dramatically.
Iacopo Franconi +4 more
semanticscholar +1 more source
Tropical Medicine and Infectious Disease, 2022 A reliable estimate of Candida parapsilosis antifungal susceptibility in candidemia patients is increasingly important to track the spread of C. parapsilosis bloodstream infections and define the true burden of the ongoing antifungal resistance.
Dina Yamin +5 more
doaj +1 more source
Journal of Fungi, 2023 Antimicrobial resistance is a matter of rising concern, especially in fungal diseases. Multiple reports all over the world are highlighting a worrisome increase in azole- and echinocandin-resistance among fungal pathogens, especially in Candida species ...
Iacopo Franconi, A. Lupetti
semanticscholar +1 more source
AFRbase: a database of protein mutations responsible for antifungal resistance
Bioinform., 2023 Motivation Fungal pathogens are known to cause life threatening invasive infections with rising global mortality rates. Besides, the indiscriminate use of antifungals in both clinics and agriculture has promoted antifungal drug resistance in the last ...
Aakriti Jain, N. Singhal, Manish Kumar
semanticscholar +1 more source
Histone Acetylation Regulator Gcn5 Mediates Drug Resistance and Virulence of Candida glabrata
Microbiology Spectrum, 2022 Candida glabrata is poised to adapt to drug pressure rapidly and acquire antifungal resistance leading to therapeutic failure. Given the limited antifungal armamentarium, there is an unmet need to explore new targets or therapeutic strategies for ...
Shuying Yu +7 more
doaj +1 more source
Molecular mechanisms governing antifungal drug resistance
npj antimicrobials and resistance, 2023 Fungal pathogens are a severe public health problem. The leading causative agents of systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus genera.
Yunjin Lee, Nicole Robbins, L. Cowen
semanticscholar +1 more source
Antifungal Resistance and the Role of New Therapeutic Agents
Current Infectious Disease Reports, 2022 Advances in health care over time have led to an evolution in the epidemiology of invasive fungal infections. There is an increasing concern for antifungal resistance and emergence of less common fungal species for which optimal therapies are not well ...
Ashley Logan, A. Wolfe, J. Williamson
semanticscholar +1 more source
bioRxiv, 2022 Drug resistant Candida auris infections are recognized by the CDC as an urgent threat. Here, we obtained and characterized a set of clinical isolates of C. auris including multiple isolates from the same patient.
Laura S. Burrack +4 more
semanticscholar +1 more source