Results 61 to 70 of about 3,376,929 (374)
bioRxiv, 2022 Conserved across all kingdoms of life, ABC transporters comprise one of the largest protein families. They are associated with multidrug resistance, affecting aspects such as resistance to antimicrobials or anti-cancer drugs.
Christopher J. Winski +3 more
semanticscholar +1 more source
Mechanisms of Antifungal Drug Resistance [PDF]
Cold Spring Harbor Perspectives in Medicine, 2014 Antifungal therapy is a central component of patient management for acute and chronic mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal drug classes. Clinical management of fungal diseases is further compromised by the emergence of antifungal drug resistance, which eliminates available drug classes as treatment ...
Cowen Leah E +4 more
openaire +2 more sources
First hospital outbreak of the globally emerging Candida auris in a European hospital [PDF]
, 2016 Background: Candida auris is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of C. auris in a London cardio-thoracic center between April 2015 and July 2016.
Abdolrasouli, A +11 more
core +2 more sources
Indian Journal of Dermatology, Venereology and Leprology, 2021 One of the canonical features of the current outbreak of dermatophytosis in India is its unresponsiveness to treatment in majority of cases. Though there appears to be discordance between in vivo and in vitro resistance, demonstration of in vitro ...
S. Verma +9 more
semanticscholar +1 more source
Antifungal Resistance on the Rise
Journal of Investigative Dermatology, 2023 Comment on : Gupta AK, Cooper EA, Wang T, Polla Ravi S, Lincoln SA, Piguet V, McCarthy LR, Bakotic WL. Detection of Squalene Epoxidase Mutations in United States Patients with Onychomycosis: Implications for Management. J Invest Dermatol. 2023 Dec;143(12):2476-2483.e7. doi: 10.1016/j.jid.2023.04.032. Epub 2023 May 24. PMID: 37236595.
Monod, Michel +2 more
openaire +2 more sources
Bloodstream yeast infections: a 15-month survey [PDF]
, 2009 A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M +3 more
core +1 more source
Molecular Mechanisms of Antifungal Resistance in Mucormycosis
BioMed Research International, 2022 Mucormycosis is one among the life-threatening fungal infections with high morbidity and mortality. It is an uncommon and rare infection targeting people with altered immunity.
P. Ganesan +6 more
semanticscholar +1 more source
Antifungal Resistance in Pathogenic Fungi [PDF]
Clinical Infectious Diseases, 2002 Pathogenic fungi are the cause of life-threatening infections in an increasing number of immunocompromised patients. The intrinsic resistance to antifungal therapy observed in some genera, along with the development of resistance during treatment in others, is becoming a major problem in the management of these diseases. We reviewed the epidemiology of
Sofia, Perea, Thomas F, Patterson
openaire +2 more sources
Antifungal Resistance and New Strategies to Control Fungal Infections
International Journal of Microbiology, 2012 Despite improvement of antifungal therapies over the last 30 years, the phenomenon of antifungal resistance is still of major concern in clinical practice.
Patrick Vandeputte +2 more
doaj +1 more source
Extensive evolution of cereal ribosome-inactivating proteins translates into unique structural features, activation mechanisms, and physiological roles [PDF]
, 2017 Ribosome-inactivating proteins (RIPs) are a class of cytotoxic enzymes that can depurinate rRNAs thereby inhibiting protein translation. Although these proteins have also been detected in bacteria, fungi, and even some insects, they are especially ...
De Zaeytijd, Jeroen, Van Damme, Els
core +2 more sources