Results 121 to 130 of about 63,671 (266)

Immunity and tolerance to infections in experimental hematopoietic transplantation [PDF]

, 2011
Resistance and tolerance are two types of host defense mechanisms that increase fitness in response to fungi. Several genetic polymorphisms in pattern recognition receptors, most remarkably Toll-like receptors (TLRs), have been described to influence ...
Agostinho Carvalho, Arbour, Balloy, Bellocchio, Bochud, Bonifazi, Bozza, Bozza, Bretz, Carvalho, Carvalho, Carvalho, Carvalho, Colonna, Cristina Cunha, Cunha, Curti, De Luca, De Luca, Desvignes, Elmaagacli, Ferwerda, Garcia-Vidal, Gribar, Kesh, Kiechl, Kontoyiannis, Luigina Romani, Mayer, Meglio, Mezger, Mitchell, Montagnoli, Naik, Paveglio, Plantinga, Romani, Romani, Romani, Romani, Romani, Sha, Wasylnka, Werner, Zelante, Zelante   +45 more
core   +1 more source

Diffusion-mediated quantification of dose-dependent antifungal drug tolerance

Antimicrobial resistance is a global health problem, with drug-resistant fungi posing major challenges for the treatment of immunocompromised patients. Antifungal tolerance is a recently discovered phenomenon whereby pathogenic fungi, including the multidrug-resistant pathogenic yeast Candidozyma (Candida) auris, grow slowly above minimum inhibitory ...
Samira Rasouli Koohi, Daniel A. Charlebois   +1 more
openaire   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]

, 2011
In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Vitali, Alberto, Vavala, Elisabetta, Marzano, Valeria, Leone, Claudia, Castagnola, Massimo, Iavarone, Federica, Angiolella, Letizia   +6 more
core   +3 more sources

Farnesol inhibits planktonic cells and antifungal-tolerant biofilms of Trichosporon asahii and Trichosporon inkin

Medical Mycology, 2019
Abstract Trichosporon species have been considered important agents of opportunistic systemic infections, mainly among immunocompromised patients. Infections by Trichosporon spp. are generally associated with biofilm formation in invasive medical devices.
Rossana de Aguiar, Cordeiro, Lívia Maria Galdino, Pereira, José Kleybson, de Sousa, Rosana, Serpa, Ana Raquel Colares, Andrade, Fernando Victor Monteiro, Portela, Antônio José de Jesus, Evangelista, Jamille Alencar, Sales, Ana Luiza Ribeiro, Aguiar, Patrícia Bruna Leite, Mendes, Raimunda Sâmia Nogueira, Brilhante, José Júlio da Costa, Sidrim, Débora de Souza Collares Maia, Castelo-Branco, Marcos Fabio Gadelha, Rocha   +13 more
openaire   +2 more sources

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis.

PLoS Pathogens
Antibiotic tolerance, by which susceptible bacteria survive at high bactericide doses, is known to cause treatment failure in clinical practice. However, the impact of antifungal tolerance on clinical outcomes remains poorly understood. Here, we observed
Yongqin Wu, Yun Zou, Yuanyuan Dai, Huaiwei Lu, Wei Zhang, Wenjiao Chang, Ying Wang, Zhengchao Nie, Yuanyuan Wang, Xiaohua Jiang   +9 more
doaj   +1 more source

The Pharmacological Potential of Mushrooms [PDF]

, 2005
This review describes pharmacologically active compounds from mushrooms. Compounds and complex substances with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and ...
Jülich, Wolf-Dieter, Lindequist, Ulrike, Niedermeyer, Timo H. J.   +2 more
core   +3 more sources

One‐Pot Ruthenium‐Catalyzed Synthesis of Benzyl/Allyl‐Halide Substituted (dihydro)naphthalenes via Radical Benzannulation

ChemistryEurope, EarlyView.
A one‐pot protocol to synthesize reactive benzyl‐ and allyl‐halide‐substituted (dihydro)naphthalenes from 2,3‐aryl‐1,3‐butadiene substrates and halogenated alkanes has been developed, using [Cp*RuCl(PPh3)2] as the catalyst. Mechanistic studies revealed an atom transfer radical addition and radical benzannulation sequence, followed by HCl elimination ...
Nicole S. van Leeuwen, David Vesseur, Thijmen Bonhoff, Jeffrey van Laar, Coert E. J. van Lare, Simon Mathew, Sonja Pullen, Joost N. H. Reek, Aalbert Zwijnenburg, Bas de Bruin   +9 more
wiley   +1 more source

In Vitro Anti-Biofilm Activities of Citral and Thymol Against Candida Tropicalis

Journal of Fungi, 2019
Candida tropicalis is an emerging non-albicans Candida species which is pathogenic to the immune-compromised humans, especially in tropical countries, including India.
Apurva Chatrath, Rashmi Gangwar, Poonam Kumari, Ramasare Prasad   +3 more
doaj   +1 more source