Results 21 to 30 of about 63,671 (266)

Tolerability profile of the current antifungal armoury [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2018
AbstractThe tolerability of available antifungal agents is essential to the final outcome of the management of invasive mycoses. There are limited classes of antifungal agents for use, and they can have serious direct toxicities and/or drug–drug interactions.
Ahmad, Mourad, John R, Perfect
openaire   +2 more sources

Candida albicans Biofilms Produce Antifungal-Tolerant Persister Cells [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2006
ABSTRACT Fungal pathogens form biofilms that are highly recalcitrant to antimicrobial therapy. The expression of multidrug resistance pumps in young biofilms has been linked to increased resistance to azoles, but this mechanism does not seem to underlie the resistance of mature biofilms that is a model of in vivo infection.
Michael D, LaFleur   +2 more
openaire   +2 more sources

Candida parapsilosis sensu stricto Antifungal Resistance Mechanisms and Associated Epidemiology

open access: yesJournal of Fungi, 2023
Fungal diseases cause millions of deaths per year worldwide. Antifungal resistance has become a matter of great concern in public health. In recent years rates of non-albicans species have risen dramatically.
Iacopo Franconi   +4 more
doaj   +1 more source

Biofilm Formation of Candida albicans Facilitates Fungal Infiltration and Persister Cell Formation in Vaginal Candidiasis

open access: yesFrontiers in Microbiology, 2020
BackgroundVaginal candidiasis is an important medical condition awaiting more effective treatment. How Candida albicans causes this disease and survives antifungal treatment is not yet fully understood.
Xueqing Wu   +12 more
doaj   +1 more source

Isolation and Identification of Spoilage Fungus in Plum and Antifungal Effects of Antifungal Agents on the Spoilage Fungus

open access: yesShipin gongye ke-ji, 2022
In this study, the spoilage fungi were isolated and identified from “Cuihong” plum, “Qingcui” plum, and “Yinhong” plum. Then the antifungal effect of ε-polylysine, natamycin, and sodium dehydroacetate on the isolated plum spoilage fungus was studied by ...
Wencheng JIAO   +4 more
doaj   +1 more source

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32 [PDF]

open access: yesFrontiers in Microbiology, 2019
Copyright © 2019 Kerenga, McKenna, Harvey, Quimbar, Garcia-Ceron, Lay, Phan, Veneer, Vasa, Parisi, Shafee, van der Weerden, Hulett, Craik, Anderson and Bleackley. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Kerenga, Bomai K   +15 more
openaire   +5 more sources

The proteasome regulator Rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress.

open access: yesPLoS Pathogens, 2023
Fungal pathogens overcome antifungal drug therapy by classic resistance mechanisms, such as increased efflux or changes to the drug target. However, even when a fungal strain is susceptible, trailing or persistent microbial growth in the presence of an ...
Ka Pui Sharon Yau   +7 more
doaj   +1 more source

Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]

open access: yes, 2017
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N   +5 more
core   +1 more source

Biostimulant Effects of Seed-Applied Sedaxane Fungicide: Morphological and Physiological Changes in Maize Seedlings [PDF]

open access: yes, 2017
Most crops are routinely protected against seed-born and soil-borne fungal pathogens through seed-applied fungicides. The recently released succinate dehydrogenase inhibitor (SDHI), sedaxane®, is a broad-spectrum fungicide, used particularly to control ...
DAL CORTIVO, Cristian   +5 more
core   +5 more sources

Saccharomyces cerevisiae biofilm tolerance towards systemic antifungals depends on growth phase [PDF]

open access: yesBMC Microbiology, 2014
Biofilm-forming Candida species cause infections that can be difficult to eradicate, possibly because of antifungal drug tolerance mechanisms specific to biofilms. In spite of decades of research, the connection between biofilm and drug tolerance is not fully understood.We used Saccharomyces cerevisiae as a model for drug susceptibility of yeast ...
Bojsen, Rasmus   +2 more
openaire   +5 more sources

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