Use of volatile fingerprints for rapid screening of antifungal agents for efficacy against dermatophyte Trichophyton species [PDF]
, 2010 The potential of using an electronic nose (E-nose) as a rapid technique for screening the responses of dermatophytes to antifungal agents was studied.
Adriaans, B +9 more
core +1 more source
Molecular characterization of cellulose synthase (CesA) genes and impact of mutations on fungicide resistance in oomycetes [PDF]
, 2012 Many oomycetes are important pathogens of plants (e.g. arable crops, fruit and forest trees), animals or microbes and, upon attacking their hosts, cause considerable economic damage mainly in agriculture and aquaculture.
Blum, Mathias
core +1 more source
Microbiology Spectrum, 2021 The high morbidity and mortality of cryptococcal meningitis is due to the limited range of therapeutic options: only three classes of antifungal drugs are available (polyenes [amphotericin B], azoles [fluconazole], and pyrimidine analogues [flucytosine]).
Feng Yang +6 more
doaj +1 more source
Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans
Frontiers in Microbiology, 2020 Candida albicans is an important human pathogen and a major concern in intensive care units around the world. C. albicans infections are associated with a high mortality despite the use of antifungal treatments.
Eric Delarze +13 more
doaj +1 more source
Tolerance of Muslim beliefs and practices: Age related differences and context effects [PDF]
, 2007 Tolerant judgments of Muslims’ political rights and dissenting beliefs and practices by ethnic Dutch adolescents (12–18 years) were examined. Participants (N = 632) made judgments of different types of behaviors and different contexts in an experimental ...
Slooter, Luuk +3 more
core +2 more sources
Candida albicans Biofilms, Heterogeneity and Antifungal Drug Tolerance [PDF]
The Open Mycology Journal, 2011 Candida albicans is a pathogenic member of the human oral and gastrointestinal microbiota. Biofilms of C. albicans form on indwelling devices, such as catheters and heart valves, and recent evidence suggests that biofilms also form on the mucosal surfaces of the mouth and vagina.
openaire +1 more source
Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence [PDF]
Molecular Microbiology, 2003 SummaryThe azole antifungal fluconazole possesses only fungistatic activity in Candida albicans and, therefore, this human pathogen is tolerant to this agent. However, tolerance to fluconazole can be inhibited when C. albicans is exposed to fluconazole combined with the immunosuppressive drug cyclosporin A, which is known to inhibit calcineurin ...
Sanglard D +4 more
openaire +3 more sources
Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi [PDF]
, 2008 Background: In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.
Borelli, Claudia +10 more
core +1 more source
Tolerability and safety of antifungal drugs
Reviews in Health Care, 2013 When treating critically ill patients, as those with fungal infections, attention should be focused on the appropriate use of drugs, especially in terms of dose, safety, and tolerability. The fungal infection itself and the concomitant physiological disorders concur to increase the risk of mortality in these patients, therefore the use of any ...
openaire +3 more sources
Frontiers in Cellular and Infection MicrobiologyAntifungal resistance and antifungal tolerance are two distinct terms that describe different cellular responses to drugs. Antifungal resistance describes the ability of a fungus to grow above the minimal inhibitory concentration (MIC) of a drug ...
Liangsheng Guo +6 more
doaj +1 more source