Combined Antifungal Resistance and Biofilm Tolerance: the Global Threat of
mSphere, 2019 The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Ryan Kean, Gordon Ramage
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Tolerability profile of the current antifungal armoury [PDF]
Journal of Antimicrobial Chemotherapy, 2018 AbstractThe tolerability of available antifungal agents is essential to the final outcome of the management of invasive mycoses. There are limited classes of antifungal agents for use, and they can have serious direct toxicities and/or drug–drug interactions.
Ahmad, Mourad, John R, Perfect
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Multifactorial Mechanisms of Tolerance to Ketoconazole in Candida albicans
Microbiology Spectrum, 2021 Candida albicans is a prevalent opportunistic human fungal pathogen for which treatment is limited to only four main classes of antifungal drugs, with the azole and echinocandin classes being used most frequently.
Yi Xu +6 more
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The Rim Pathway Mediates Antifungal Tolerance in Candida albicans through Newly Identified Rim101 Transcriptional Targets, Including Hsp90 and Ipt1. [PDF]
Antimicrobial Agents and Chemotherapy, 2018 Jerome Govin +2 more
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Candida parapsilosis sensu stricto Antifungal Resistance Mechanisms and Associated Epidemiology
Journal of Fungi, 2023 Fungal diseases cause millions of deaths per year worldwide. Antifungal resistance has become a matter of great concern in public health. In recent years rates of non-albicans species have risen dramatically.
Iacopo Franconi +4 more
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Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32 [PDF]
Frontiers in Microbiology, 2019 Copyright © 2019 Kerenga, McKenna, Harvey, Quimbar, Garcia-Ceron, Lay, Phan, Veneer, Vasa, Parisi, Shafee, van der Weerden, Hulett, Craik, Anderson and Bleackley. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Kerenga, Bomai K +15 more
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Frontiers in Microbiology, 2020 BackgroundVaginal candidiasis is an important medical condition awaiting more effective treatment. How Candida albicans causes this disease and survives antifungal treatment is not yet fully understood.
Xueqing Wu +12 more
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Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in
mBio, 2021 How cells exposed to one stress are later able to better survive other types of stress is not well understood. In eukaryotic organisms, physiological and pathological stresses can disturb endoplasmic reticulum (ER) function, resulting in “ER stress ...
Feng Yang +7 more
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Trichosporon asahii and Trichosporon inkin Biofilms Produce Antifungal-Tolerant Persister Cells [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Persister cells are metabolically inactive dormant cells that lie within microbial biofilms. They are phenotypic variants highly tolerant to antimicrobials and, therefore, associated with recalcitrant infections. In the present study, we investigated ifTrichosporon asahiiandT. inkinare able to produce persister cells.Trichosporonspp.
Rossana de Aguiar Cordeiro +10 more
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Shipin gongye ke-ji, 2022 In this study, the spoilage fungi were isolated and identified from “Cuihong” plum, “Qingcui” plum, and “Yinhong” plum. Then the antifungal effect of ε-polylysine, natamycin, and sodium dehydroacetate on the isolated plum spoilage fungus was studied by ...
Wencheng JIAO +4 more
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