Results 81 to 90 of about 63,671 (266)
Diversity of Heavy Metals Tolerant and Antifungal Sensitive Fungal Community of River Ganga
Ganga is the largest river in India and has both religious and economical importance to our country. Ganga water has very important reverence in various religious ceremonies as holy water along it had been used for drinking and irrigation purpose. In developing cites such as Haridwar Ganga start facing water pollution problems but still its water ...
Vani Sharma, Padma Singh
openaire +1 more source
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti +11 more
wiley +1 more source
Drug Resistance and Novel Therapeutic Approaches in Invasive Candidiasis
Candida species are the leading cause of invasive fungal infections worldwide and are associated with acute mortality rates of ~50%. Mortality rates are further augmented in the context of host immunosuppression and infection with drug-resistant Candida ...
Sarah E. Murphy +2 more
doaj +1 more source
The pathogenesis-related protein PR-4 from Theobroma cacao has antifungal activity and induces ROS in Moniliophthora perniciosa : S03O02 [PDF]
The pathogenesis-related proteins class 4 (PR-4) are known to be involved in plant defense response and/or related stress situations. The objective of this study was to evaluate the antifungal activity and reactive oxygen species (ROS) production of the ...
Gesteira, Abelmon S. +5 more
core
Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]
A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core +4 more sources
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C.
Yi Xu +8 more
doaj +1 more source
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Detection of Hog1 Phosphorylation in Candida albicans in Response to an Antifungal Protein
It is becoming increasingly apparent that stress signalling is important for tolerance of fungal species to antifungal chemicals and proteins. The high-osmolarity glycerol (HOG) pathway responds to a number of stressors including osmotic and oxidative ...
Brigitte Hayes, Nicole Weerden
doaj +1 more source

