Results 71 to 80 of about 511,571 (224)

Physiological and therapeutic relevance of T cell receptor-mediated antigen trogocytosis

Biomedical Journal
Trogocytosis is an active process whereby fragments of plasma membrane proteins and cytoplasm are transferred from one cell to another in a cell-cell contact-dependent manner. T cells trogocytose pieces of the cells presenting antigen to them at the site
Nuria Martinez-Martin, Balbino Alarcon
doaj   +1 more source

Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8+ and CD4+CD8+ T Cells

Frontiers in Immunology, 2019
Natural killer (NK) cells belong to the innate immune system and play a central role in the defense against viral infections and cancer development, but also contribute to shaping adaptive immune responses.
Steffi De Pelsmaeker, Bert Devriendt, Nick De Regge, Herman W. Favoreel   +3 more
doaj   +1 more source

Trichostatin a Protects Dendritic Cells Against Oxygen-Glucose Deprivation via the SRSF3/PKM2/Glycolytic Pathway

Frontiers in Pharmacology, 2018
Dendritic cells (DCs) are important to the immune system and are frequently recruited to hypoxic regions, especially during acute myocardial infarction (AMI).
Hongyun Jiang, Siwei Zhang, Tongtong Song, Xin Guan, Ruojin Zhang, Xia Chen   +5 more
doaj   +1 more source

What lies beneath the airway mucosal barrier? Throwing the spotlight on antigen‐presenting cell function in the lower respiratory tract

Clinical & Translational Immunology, 2020
The global prevalence of respiratory infectious and inflammatory diseases remains a major public health concern. Prevention and management strategies have not kept pace with the increasing incidence of these diseases. The airway mucosa is the most common
Saparna Pai, Visai Muruganandah, Andreas Kupz   +2 more
doaj   +1 more source

Correlations in the T Cell Response to Altered Peptide Ligands

, 2004
The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases.
Arstila, Bachmann, Bachmann, Blattman, Bogarad, Chandler, Deem, Derrida, Derrida, Drossel, Garboczi, Garcia, Jeong-Man Park, Kauffman, Kedl, Kesmir, Klenerman, Lee, Lee, Martin, Michael W. Deem, Perelson, Perelson, Schodin, Singh, Sloan-Lancaster, Sourdive   +26 more
core   +1 more source

Large Scale Ex Vivo Expansion of γδ T cells Using Artificial Antigen-presenting Cells

, 2022
Justin C. Boucher, Bin Yu, Gongbo Li, Bishwas Shrestha, David A. Sallman, Ana Marie Landin, Cheryl A. Cox, Kumar Karyampudi, Claudio Anasetti, Marco L. Davila, Nelli Bejanyan   +10 more
openalex   +2 more sources

Expression of cluster of differentiation 1a-positive langerhans cells in oral lichen planus

Indian Journal of Dermatology, 2019
Background/Purpose: Lichen planus is a T-cell-mediated mucocutaneous disorder characterized histopathologically by a band of chronic inflammatory cells in the subepithelial zone and degeneration of basal layer. The present study was aimed to evaluate the
Thankanadar Arul Kumar, Veeran Veeravarmal, Ramdas Madhavan Nirmal, Ramamoorthy Amsaveni, Mohamed Hanifa Mohamed Nassar, Ganesan Kesavan   +5 more
doaj   +1 more source

Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection

Frontiers in Immunology, 2018
One of the major contributions to protective immunity to influenza viruses that is provided by virus-specific CD4 T cells is delivery of effector function to the infected lung.
Katherine A. Richards, Anthony T. DiPiazza, Anthony T. DiPiazza, Ajitanuj Rattan, Zackery A. G. Knowlden, Hongmei Yang, Andrea J. Sant   +6 more
doaj   +1 more source

CD4 T Cell Responses to Theileria parva in Immune Cattle Recognize a Diverse Set of Parasite Antigens Presented on the Surface of Infected Lymphoblasts [PDF]

, 2021
W. Ivan Morrison, Adriana Aguado, Tara A. Sheldrake, Nicholas C. Palmateer, Olukemi O. Ifeonu, Kyle Tretina, K.R. Parsons, Emilio Fenoy, Timothy Connelley, Morten Nielsen, Joana C. Silva   +10 more
openalex   +1 more source

Antigen Presentation by Extracellular Vesicles from Professional Antigen-Presenting Cells

Annual Review of Immunology, 2018
The initiation and maintenance of adaptive immunity require multifaceted modes of communication between different types of immune cells, including direct intercellular contact, secreted soluble signaling molecules, and extracellular vesicles (EVs). EVs can be formed as microvesicles directly pinched off from the plasma membrane or as exosomes secreted ...
Lindenbergh, Marthe F S, Stoorvogel, Willem   +1 more
openaire   +2 more sources