Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component [PDF]
, 1996 The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core
A computational study of the statistical mechanics of antibody-antigen conformations [PDF]
arXiv, 2004 We describe the representation of the chemical affinity between the antigen-combining site of the immunoglobulin molecule and the antigen molecule as the probability of the two molecules existing in a bound state. Our model is based on the identification of shape attractors in the configuration space for the joint antibody / antigen combining site ...
arxiv
Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells [PDF]
, 2012 Dendritic cells (DCs) can initiate and shape host immune responses toward either immunity or tolerance by their effects on antigen-specific CD4(+) T cells.
Akira +66 more
core +2 more sources
Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model
Frontiers in Immunology, 2017 Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP) models for studying human immunodeficiency virus (HIV)-1 biology and pathogenesis.
Jiae Kim +11 more
doaj +1 more source
A General Theory for Direct Quantitative Analysis of Antigen [PDF]
arXiv, 2011 A theory for direct quantitative analysis of an antigen is proposed. It is based on a potential homogenous immunoreaction system. It establishes an equation to describe the concentration change of the antigen and antibody complex. A maximum point is found in the concentration profile of the complex which can be used to calculate the concentration of ...
arxiv
Early signaling defects in human T cells anergized by T cell presentation of autoantigen. [PDF]
, 1992 Major histocompatibility complex class II-positive human T cell clones are nontraditional antigen-presenting cells (APCs) that are able to simultaneously present and respond to peptide or degraded antigen, but are unable to process intact protein ...
Freeman, GJ +4 more
core
A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes [PDF]
, 1989 Peptides that are antigenic for T lymphocytes are ligands for two receptors, the class I or II glycoproteins that are encoded by genes in the major histocompatibility complex, and the idiotypic / chain T-cell antigen receptor1–9. That a peptide must bind
A Sette +30 more
core +1 more source
The use of quantum dots to amplify antigen detection [PDF]
arXiv, 2017 Proposal to develop an Improved immunological assay employing primary IgG antibodies and secondary IgM antibodies labeled with quantum dots to amplify antigen detection.
arxiv
The serlogical specificity of the lectin from Lens culinaris [PDF]
, 1973 Lens culinaris, the common lentil, contains a lectin which has been shown to be specific for a glycoprotein saliva antigen and a glycolipoprotein serum antigen.
Heritage, Deborah Ward
core +1 more source
Canalization of the evolutionary trajectory of the human influenza virus [PDF]
arXiv, 2011 Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like genealogical tree. Here, we use a large-scale individual-based model to show that evolution in a Euclidean
arxiv