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Cellular Assays to Monitor Antigen Cross-presentation In Vitro
Antigen cross-presentation is a functional feature of some specialized antigen-presenting cells, allowing them to internalize and process antigens from extracellular sources and present them via major histocompatibility class I (MHC-I) molecules to CD8+ T lymphocytes.François-Xavier, Mauvais +1 more
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Apoptosis, cross-presentation, and the fate of the antigen specific immune response
Apoptosis, 2000Induction of cell death by apoptosis, also called programmed cell death, and clearance of apoptotic bodies by scavenger cells has long thought to be an efficient means to dispose of unwanted cells without causing inflammatory responses able to mediate specific reactions.
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Introduction to the special issue: Antigen cross-presentation
Seminars in Immunology, 2023openaire +2 more sources
Mechanisms of Hsp70-Mediated Antigen Cross-Presentation
2007Hsp70 is a highly conserved, ubiquitous molecule and its properties as a molecular chaperone are well-described. Additionally, it has been shown to carry out important functions in the mammalian immune system. This study addressed several open questions concerning the interaction of Hsp70 with the surface of antigen presenting cells and the mechanism ...
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Analysis of direct and cross-presentation of antigens in TPPII knockout mice.
Journal of immunology (Baltimore, Md. : 1950), 2007Tripeptidyl peptidase II (TPPII) is an oligopeptidase forming giant complexes in the cytosol that have high exo-, but also, endoproteolytic activity. Immunohistochemically, the complexes appear as distinct foci in the cytosol. In part controversial biochemical and functional studies have suggested that TPPII contributes, on the one hand, positively to ...
Firat, Elke +7 more
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Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung
Cell Reports, 2022Masahiro Kitabatake
exaly
Mechanism of cross-presentation of microencapsulated antigen
Journal of Controlled Release, 2011openaire +2 more sources
Perforin 2 mediates endosomal antigen export for cross-presentation
Nature Reviews Immunology, 2023Aljawharah Alrubayyi +1 more
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Spotlight on TAP and its vital role in antigen presentation and cross-presentation
Molecular Immunology, 2022Barzan A Sadiq +2 more
exaly