Results 11 to 20 of about 1,150,441 (351)

Antigen-presenting cells and antigen presentation in tertiary lymphoid organs [PDF]

Frontiers in Immunology, 2016
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Bedaj, Marija, Benson, Robert A., Hughes, Catherine E., Maffia, Pasquale   +3 more
core   +10 more sources

Antigen Presentation in the Lung

Frontiers in Immunology, 2022
The lungs are constantly exposed to environmental and infectious agents such as dust, viruses, fungi, and bacteria that invade the lungs upon breathing. The lungs are equipped with an immune defense mechanism that involves a wide variety of immunological cells to eliminate these agents.
Kawasaki, Takumi, Ikegawa, Moe, Kawai, Taro   +2 more
openaire   +4 more sources

Tumor-derived microvesicles modulate antigen cross-processing via reactive oxygen species-mediated alkalinization of phagosomal compartment in dendritic cells [PDF]

Frontiers in Immunology, 2017
Dendritic cells (DCs) are the only antigen-presenting cells able to prime naïve T cells and cross-prime antigen-specific CD8+ T cells. Their functionality is a requirement for the induction and maintenance of long-lasting cancer immunity.
Aurelia Rughetti, Chiara Napoletano, Fabio Altieri, Federico Battisti, Filippo Bellati, Filippo Bellati, Francesca Belleudi, Giulio Caracciolo, Hassan Rahimi Koshkaki, Ilaria Grazia Zizzari, Ilary Ruscito, Ilary Ruscito, Maria Rosaria Torrisi, Maria Rosaria Torrisi, Marianna Nuti, Pierluigi Benedetti Panici, Sara Palchetti   +16 more
core   +12 more sources

Antigen Cross-Presentation by Macrophages [PDF]

Frontiers in Immunology, 2020
The contribution of dendritic cell (DC) antigen cross-presentation to the activation of CD8+ T lymphocytes for immune defense against tumors, viruses, and intracellular pathogens has been recognized widely. Although originally thought to be an exclusive characteristic of DCs, recently also other immune cells, particularly macrophages, have been shown ...
Elke M. Muntjewerff, Luca D. Meesters, Geert van den Bogaart, Geert van den Bogaart   +3 more
openaire   +6 more sources

Regulation of T cell expansion by antigen presentation dynamics [PDF]

PNAS 2019, 116 (13) 5914-5919, 2018
An essential feature of the adaptive immune system is the proliferation of antigen-specific lymphocytes during an immune reaction to form a large pool of effector cells.
Mayer, Andreas, Perelson, Alan S., Wingreen, Ned S., Zhang, Yaojun   +3 more
core   +2 more sources

Antigen Presentation the Macrophage Way [PDF]

Cell, 2007
Multiphoton intravital microscopy of lymph nodes has revolutionized the study of the early events leading to induction of acquired immunity. Using this technique, Junt et al.
Santos, Luciana dos, Jacoby, Thalita Silva, Ness, Sandro Luis Ribeiro, Guerra, Gerson, Wayhs, Carlos Alberto Yasin   +4 more
core   +5 more sources

Antigen Presentation by Vascular Cells [PDF]

Frontiers in Immunology, 2017
Antigen presentation by cells of the vessel wall may initiate rapid and localized memory immune responses in peripheral tissues. Peptide antigens displayed on major histocompatibility complex (MHC) molecules on the surface of endothelial cells (ECs) can be recognized by T cell receptors on circulating effector memory T cells (TEM), triggering both ...
Rebecca Liu, Jordan S. Pober, Thomas D. Manes, Jonathan Merola   +3 more
openaire   +5 more sources

Antigen processing and presentation an overview [PDF]

Memórias do Instituto Oswaldo Cruz, 1992
Udgivelsesdato: 1992 ...
Soren Buus
openaire   +5 more sources

In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei

Vaccines, 2021
Murine dendritic cells, when pulsed with heat-killed Burkholderia pseudomallei and used to immunise naïve mice, have previously been shown to induce protective immunity in vivo. We have now demonstrated the in vitro priming of naïve human T cells against
Durga Reddi, Lydia Durant, David Bernardo, Alistair Noble, Nicholas R. English, Philip Hendy, Graeme C. Clark, Joann L. Prior, Ethel Diane Williamson, Stella C. Knight   +9 more
doaj   +1 more source

Co-Stimulatory Bispecific Antibodies Induce Enhanced T Cell Activation and Tumor Cell Killing in Breast Cancer Models

Frontiers in Immunology, 2021
Although T cell-recruiting CD3-binding bispecific antibodies (BiMAb) have been proven to be clinically effective for hematologic malignancies, the success of BiMAb targeting solid tumor-associated antigens (TAA) in carcinomas so far remains poor.
Karsten M. Warwas, Karsten M. Warwas, Marten Meyer, Marten Meyer, Márcia Gonçalves, Márcia Gonçalves, Gerhard Moldenhauer, Nadja Bulbuc, Susanne Knabe, Claudia Luckner-Minden, Claudia Ziegelmeier, Claus Peter Heussel, Claus Peter Heussel, Claus Peter Heussel, Inka Zörnig, Dirk Jäger, Dirk Jäger, Frank Momburg, Frank Momburg   +18 more
doaj   +1 more source