Results 11 to 20 of about 522,409 (333)

Antigen Cross-Presentation by Macrophages [PDF]

open access: yesFrontiers in Immunology, 2020
The contribution of dendritic cell (DC) antigen cross-presentation to the activation of CD8+ T lymphocytes for immune defense against tumors, viruses, and intracellular pathogens has been recognized widely.
Elke M. Muntjewerff   +3 more
doaj   +5 more sources

Antigen Presentation in the Gut [PDF]

open access: yesCanadian Journal of Gastroenterology, 1990
The induction of T cell responses requires recognition of antigens in association with class II major histocompatibility complex (MHC) proteins and specialized antigen-presenting cells.
W Doe, P Pavli
doaj   +2 more sources

Antigen Presentation by Vascular Cells [PDF]

open access: yesFrontiers in Immunology, 2017
Antigen presentation by cells of the vessel wall may initiate rapid and localized memory immune responses in peripheral tissues. Peptide antigens displayed on major histocompatibility complex (MHC) molecules on the surface of endothelial cells (ECs) can ...
Jordan S. Pober   +3 more
doaj   +4 more sources

Tumor Antigen Presentation by Dermal Antigen-Presenting Cells [PDF]

open access: yesJournal of Investigative Dermatology, 2000
Several phenotypes of antigen-presenting cells are present in the dermis, where they presumably function to present encountered antigens for immune responses. This study examined the ability of dermal antigen-presenting cells to present tumor-associated antigens for the induction of in vivo antitumor immunity.
Edward Miranda   +8 more
openaire   +3 more sources

Presentation of hepatocellular antigens [PDF]

open access: yesCellular & Molecular Immunology, 2016
The liver is an organ in which antigen-specific T-cell responses manifest a bias toward immune tolerance. This is clearly seen in the rejection of allogeneic liver transplants, and multiple other phenomena suggest that this effect is more general.
Arash Grakoui, Ian N. Crispe
openaire   +3 more sources

Pathogenicity of anti-ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. [PDF]

open access: yes, 2015
BACKGROUND: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Crawley, JT   +3 more
core   +2 more sources

Antigen presentation in uveitis [PDF]

open access: yesEye, 1997
Experimental autoimmune uveoretinits (EAU) is not only a valuable model for human inflammatory eye diseases, it is also a useful system for studying many aspects of immunobiology. One such aspect is self/non-self discrimination, the ability of the immune system to tolerate self molecules while responding aggressively to foreign antigens. Our laboratory
Shiv A. Prasad, Dale S. Gregerson
openaire   +3 more sources

Poly(2-propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation. [PDF]

open access: yes, 2017
Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner.
Bracho-Sanchez, Evelyn   +6 more
core   +1 more source

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer: a novel mechanism for enhancing specific antigen presentation [PDF]

open access: yes, 2007
The B cell antigen receptor (BCR) efficiently facilitates the capture and processing of a specific antigen for presentation on MHC class II molecules to antigen specific CD4+ T cells (1).
Ben J. C. Quah   +5 more
core   +2 more sources

Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

open access: yesFrontiers in Immunology, 2023
CD8 T cells are important antiviral effectors in the adaptive immune response to cytomegaloviruses (CMV). Naïve CD8 T cells can be primed by professional antigen-presenting cells (pAPCs) alternatively by “direct antigen presentation” or “antigen cross ...
Julia K. Büttner   +8 more
doaj   +1 more source

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