Results 11 to 20 of about 953,664 (316)
Tumor Antigen Presentation by Dermal Antigen-Presenting Cells [PDF]
Journal of Investigative Dermatology, 2000 Several phenotypes of antigen-presenting cells are present in the dermis, where they presumably function to present encountered antigens for immune responses. This study examined the ability of dermal antigen-presenting cells to present tumor-associated antigens for the induction of in vivo antitumor immunity.
Edward Miranda +8 more
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Microbiome, 2020 Background Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface.
Lydia Durant +19 more
doaj +1 more source
The role of antigen-competitive dynamics in regulating the immune response [PDF]
Bulletin of Mathematical Biology, 83(5): 40 (2021), 2021 The clonal expansion of T cells during an infection is tightly regulated to ensure an appropriate immune response against invading pathogens. Although experiments have mapped the trajectory from expansion to contraction, the interplay between mechanisms that control this response are not fully understood.
arxiv +1 more source
Frontiers in Genetics, 2020 The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón +6 more
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Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation
Frontiers in Immunology, 2021 Major histocompatibility class I (MHC I) molecules bind peptides derived from a cell's expressed genes and then transport and display this antigenic information on the cell surface.
Karthik Dhatchinamoorthy +2 more
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Presentation of hepatocellular antigens [PDF]
Cellular & Molecular Immunology, 2016 The liver is an organ in which antigen-specific T-cell responses manifest a bias toward immune tolerance. This is clearly seen in the rejection of allogeneic liver transplants, and multiple other phenomena suggest that this effect is more general.
Arash Grakoui, Ian N. Crispe
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Antigen presentation in uveitis [PDF]
Eye, 1997 Experimental autoimmune uveoretinits (EAU) is not only a valuable model for human inflammatory eye diseases, it is also a useful system for studying many aspects of immunobiology. One such aspect is self/non-self discrimination, the ability of the immune system to tolerate self molecules while responding aggressively to foreign antigens. Our laboratory
Shiv A. Prasad, Dale S. Gregerson
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Chemotherapy enhances cross-presentation of nuclear tumor antigens. [PDF]
PLoS ONE, 2014 Cross-presentation of tumor antigen is essential for efficient priming of naïve CD8⁺ T lymphocytes and induction of effective anti-tumor immunity. We hypothesized that the subcellular location of a tumor antigen could affect the efficiency of cross ...
Chidozie C Anyaegbu +4 more
doaj +1 more source
Frontiers in Immunology, 2023 CD8 T cells are important antiviral effectors in the adaptive immune response to cytomegaloviruses (CMV). Naïve CD8 T cells can be primed by professional antigen-presenting cells (pAPCs) alternatively by “direct antigen presentation” or “antigen cross ...
Julia K. Büttner +8 more
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Antigenic waves of virus-immune co-evolution [PDF]
, 2021 The evolution of many microbes and pathogens, including circulating viruses such as seasonal influenza, is driven by immune pressure from the host population. In turn, the immune systems of infected populations get updated, chasing viruses even further away.
arxiv +1 more source