Results 31 to 40 of about 3,217,603 (374)
Chemotherapy enhances cross-presentation of nuclear tumor antigens. [PDF]
PLoS ONE, 2014 Cross-presentation of tumor antigen is essential for efficient priming of naïve CD8⁺ T lymphocytes and induction of effective anti-tumor immunity. We hypothesized that the subcellular location of a tumor antigen could affect the efficiency of cross ...
Chidozie C Anyaegbu +4 more
doaj +1 more source
Science Advances, 2020 A micropeptide encoded by MIR155HG modulates antigen presentation and suppresses autoinflammation through binding to HSC70. Many annotated long noncoding RNAs (lncRNAs) harbor predicted short open reading frames (sORFs), but the coding capacities of ...
Liman Niu +18 more
semanticscholar +1 more source
Cancers, 2021 Simple Summary A new class of drugs, termed Immune Checkpoint Inhibitors, has revolutionized cancer therapy during the last few years. Unfortunately, these drugs are only effective for a subset of patients and cancer types. Recent work has suggested that
A. Mpakali, E. Stratikos
semanticscholar +1 more source
Promising Extracellular Vesicle-Based Vaccines against Viruses, Including SARS-CoV-2
Biology, 2021 Extracellular vesicles (EVs) are secreted from almost all human cells and mediate intercellular communication by transferring heterogeneous molecules (i.e., DNA, RNAs, proteins, and lipids).
Berina Sabanovic +3 more
doaj +1 more source
A generic polymer-protein ligation strategy for vaccine delivery [PDF]
, 2016 Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens.
De Geest, Bruno +6 more
core +1 more source
Antigen presentation in uveitis [PDF]
Eye, 1997 Experimental autoimmune uveoretinits (EAU) is not only a valuable model for human inflammatory eye diseases, it is also a useful system for studying many aspects of immunobiology. One such aspect is self/non-self discrimination, the ability of the immune system to tolerate self molecules while responding aggressively to foreign antigens. Our laboratory
S A, Prasad, D S, Gregerson
openaire +2 more sources
MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation.
Journal of Clinical Investigation, 2020 Immune evasion is a pivotal event in tumor progression. To eliminate human cancer cells, current immune checkpoint therapy is set to boost the CD8+ T cell-mediated cytotoxicity. However, this action is eventually dependent on the efficient recognition of
Yuanzhang Fang +20 more
semanticscholar +1 more source
Mediators of Inflammation, 2013 Background. Dendritic cells regulate immune responses to microbial products and play a key role in ulcerative colitis (UC) pathology. We determined the immunomodulatory effects of probiotic strain Lactobacillus casei Shirota (LcS) on human DC
Elizabeth R. Mann +12 more
doaj +1 more source
Identification and molecular characterization of oat peptides implicated on coeliac immune response
Food & Nutrition Research, 2016 Background: Oats provide important nutritional and pharmacological properties, although their safety in coeliac patients remains controversial. Previous studies have confirmed that the reactivity of the anti-33-mer monoclonal antibody with different oat ...
Isabel Comino +11 more
doaj +1 more source
HLA-E Peptide Repertoire and Dimorphism—Centerpieces in the Adaptive NK Cell Puzzle?
Frontiers in Immunology, 2018 Adaptive Natural Killer (NK) cells, a heterogenous subpopulation of human NK cells with a unique phenotypic and functional signature, became arguably one of the central areas of interest in the field.
Alexander Rölle +4 more
doaj +1 more source