Results 121 to 130 of about 18,685 (221)

Casting a wider net: Immunosurveillance by nonclassical MHC molecules.

PLoS Pathogens, 2019
Most studies of T lymphocytes focus on recognition of classical major histocompatibility complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous variations and exceptions of biological significance based on recognition of a
M Patricia D'Souza, Erin Adams, John D Altman, Michael E Birnbaum, Cesar Boggiano, Giulia Casorati, Yueh-Hsiu Chien, Anthony Conley, Sidonia Barbara Guiomar Eckle, Klaus Früh, Timothy Gondré-Lewis, Namir Hassan, Huang Huang, Lakshmi Jayashankar, Anne G Kasmar, Nina Kunwar, Judith Lavelle, David M Lewinsohn, Branch Moody, Louis Picker, Lakshmi Ramachandra, Nilabh Shastri, Peter Parham, Andrew J McMichael, Jonathan W Yewdell   +24 more
doaj   +1 more source

Using Surface Immunogenic Protein as a Carrier Protein to Elicit Protective Antibody to Multiple Serotypes for Candidate Group B Streptococcal Glycan Conjugate Vaccines

Vaccines
Group B Streptococcus (GBS) is a life-threatening opportunistic pathogen, particularly in pregnant women, infants, and the elderly. Currently, maternal vaccination is considered the most viable long-term option for preventing GBS mother-to-infant ...
Huiqi Duan, Wenhua Huang, Qingyu Lv, Peng Liu, Qian Li, Decong Kong, Xuyang Sun, Xinran Zhang, Yongqiang Jiang, Shaolong Chen   +9 more
doaj   +1 more source

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]

, 1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB, Erle, DJ, Folkesson, HG, Locksley, RM, Matthay, MA, Warnock, ML, Wiener-Kronish, JP   +6 more
core  

Role of Donor Unrestricted T Cells (DURTs) in TB Host Defense: Implications for Novel TB Vaccine Development

Vaccines
Tuberculosis (TB) is the leading cause of infectious disease-related death globally. Most TB vaccine strategies have focused on conventional CD4 T cell responses, but to date, these have failed to deliver durable sterilizing protection.
Dylan Kain, David Michael Lewinsohn, Deborah Anne Lewinsohn   +2 more
doaj   +1 more source

Immunology of tuberculosis [PDF]

, 2004
Tuberculosis is a major health problem throughout the world causing large number of deaths, more than that from any other single infectious disease. The review attempts to summarize the information available on host immune response to Mycobacterium ...
Raja, Alamelu
core  

Evidence for clonal selection of gamma/delta T cells in response to a human pathogen. [PDF]

, 1991
T cells bearing gamma/delta antigen receptors comprise a resident population of intraepithelial lymphocytes in organs such as skin, gut, and lungs, where they are strategically located to contribute to the initial defense against infection.
Band, H, Deans, RJ, Modlin, RL, Morita, CT, Ohmen, J, Panchamoorthy, G, Rea, TH, Uyemura, K   +7 more
core  

[CD1 molecules--mechanisms of lipid antigens presentation].

Postepy higieny i medycyny doswiadczalnej, 2004
This review summarizes the status of our knowledge on the structure, expression and function of CD1 proteins. An endosomal and non-endosomal pathways of CD1 antigen presentation are also described.
openaire   +1 more source

Editorial: Community series in the role of CD1- and MR1-restricted T cells in immunity and disease: volume III. [PDF]

Front Immunol
Iwabuchi K, Van Kaer L.
europepmc   +1 more source

Detergents alter the stability and lipid binding properties of the CD1d immunoreceptor. [PDF]

Protein Sci
Miles UZ, Finn MG, McShan AC.
europepmc   +1 more source

Insights into the Biochemical and Immune Mechanisms in Drug-Induced Liver Injury Pathogenesis. [PDF]

Chem Res Toxicol
Saville E, Wells G, Farrell L, Naisbitt DJ, Meng X.   +4 more
europepmc   +1 more source