Results 111 to 120 of about 18,685 (221)
A Potent and Effective Suicidal Listeria Vaccine Platform. [PDF]
, 2019 Live-attenuated Listeria monocytogenes has shown encouraging potential as an immunotherapy platform in preclinical and clinical settings. However, additional safety measures will enable application across malignant and infectious diseases.
Benanti, Erin L +12 more
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Role of innate T cells in anti-bacterial immunity [PDF]
, 2015 Innate T cells are a heterogeneous group of αβ and γδ T cells that respond rapidly (
Aggarwal +100 more
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Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine
Journal of Translational Medicine, 2019 Background In non-human primates (NHPs) and humans, partial protection from HIV/SIV infection or suppression of replication is achievable by Env-binding antibodies and Gag-specific CD8+ T-cells targeting protective epitopes.
Melanie Schwerdtfeger +3 more
doaj +1 more source
A novel adjuvant-free H fusion system for the production of recombinant immunogens in Escherichia coli : Its application to a 12 kDa antigen from Cryptosporidium parvum [PDF]
, 2013 The production of recombinant antigens in Escherichia coli and specific polyclonal antibodies for diagnosis and therapy is still a challenge for world-wide researchers.
Almeida, André +5 more
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Acta Dermato-Venereologica, 2017 Folliculotropic mycosis fungoides (FMF), a variant of mycosis fungoides (MF) with distinct clinical features, is characterized by infiltration of malignant T cells in hair follicles.
Panagiota Mantaka +6 more
doaj +1 more source
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]
, 2018 CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar +7 more
core +6 more sources
Diverse antigen presentation by the Group 1 CD1 molecule, CD1c [PDF]
Molecular Immunology, 2013 CD1 molecules are Major Histocompatibility Complex (MHC) class I-like proteins that present diverse lipid antigens to T cells. Most of our understanding of CD1 lipid presentation and T cell recognition has come from study of the invariant Natural Killer T cell recognition of CD1d.
openaire +2 more sources
Frontiers in Immunology, 2018 The last two decades saw a dramatic reduction in malaria incidence rates, but this decrease has been stalling recently, indicating control measures are starting to fail. An effective vaccine, particularly one with a marked effect on disease transmission,
Florian Brod +8 more
doaj +1 more source
An Alternative Path for Antigen Presentation: Group 1 CD1 Proteins [PDF]
The Journal of Immunology, 2010 The epochal discovery of a technique for producing mAbs of defined specificity by Georges Kohler and Cesar Milstein ([1][1]) led to many important advances in life sciences and spawned a large industry for production of these Abs for research, diagnosis, and therapy.
openaire +2 more sources
Delineation of human thymocytes with or without functional potential by CD1-specific antibodies [PDF]
, 2017 Hematopoletic precursors lacking T cell antigen receptors TCR-CD3−) and CD4 and CD8 surface markers (i.e. double-negative thymocytes) give rise to functionally mature T iymphocytes.
de la Hera, Antonio +2 more
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