Results 101 to 110 of about 11,539 (211)
Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine
Journal of Translational Medicine, 2019 Background In non-human primates (NHPs) and humans, partial protection from HIV/SIV infection or suppression of replication is achievable by Env-binding antibodies and Gag-specific CD8+ T-cells targeting protective epitopes.
Melanie Schwerdtfeger +3 more
doaj +1 more source
Acta Dermato-Venereologica, 2017 Folliculotropic mycosis fungoides (FMF), a variant of mycosis fungoides (MF) with distinct clinical features, is characterized by infiltration of malignant T cells in hair follicles.
Panagiota Mantaka +6 more
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Antigen presentation and recognition in bacterial infections.
, 2005 Antigen processing and recognition is a key feature of antibacterial immune responses to intracellular bacteria. In contrast to viruses, which are primarily controlled by conventional MHC II- and MHC I-restricted CD4+ or CD8+ T cells, respectively ...
Kaufmann, Stefan He +3 more
core +1 more source
Frontiers in Immunology, 2018 The last two decades saw a dramatic reduction in malaria incidence rates, but this decrease has been stalling recently, indicating control measures are starting to fail. An effective vaccine, particularly one with a marked effect on disease transmission,
Florian Brod +8 more
doaj +1 more source
Detection of CD1 mRNA in Paneth cells of the mouse intestine by in situ hybridization.
, 1992 Cluster of differentiation 1 (CD1) antigens are a family of non-MHC but Class I-like molecules that have been identified in humans and rodents. Although their function(s) remains unknown, it has been proposed that CD1 may present antigens to specific ...
J Lacasse, L H Martin
core +1 more source
How T lymphocytes recognize lipid antigens
, 2006 Recognition of lipid antigens by T lymphocytes is well established. Lipids are recognized by T cells when presented in association with CD1 antigen-presenting molecules.
Lucia Mori +3 more
core +1 more source
Casting a wider net: Immunosurveillance by nonclassical MHC molecules.
PLoS Pathogens, 2019 Most studies of T lymphocytes focus on recognition of classical major histocompatibility complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous variations and exceptions of biological significance based on recognition of a
M Patricia D'Souza +24 more
doaj +1 more source
Physical and functional association of CD45 and CD3-TCR complex on CD1 + human thymocytes. Evidence that the engagement of CD45 molecules can prevent CD1 + thymocytes from apoptosis [PDF]
, 2020 In this study the effects of CD45 engagement on CD3-TCR-driven stimulation of CD1 + human immature thymocytes have been analyzed. Simultaneous cross-linking of CD45 and CD3 antigens on highly purified CD1 + thymocytes reduced the number of cells ...
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CD1 genotyping of patients with Mycobacterium Malmoense pulmonary disease
, 2001 Mycobacterium malmoense is an opportunistic mycobacterium. Little is known about genetic susceptibility to opportunistic mycobacterial infection. As CD1 molecules are capable of presenting antigens from the more virulent M.
Barnardo, M.C.N.M. +5 more
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The molecular basis of CD1-mediated presentation of lipid antigens
The CD1 family of proteins mediates a newly described pathway for presentation of lipids and glycolipids for specific recognition by T cells. All four of the known human CD1 proteins (CD1a, CD1b, CD1c and CD1d) as well as murine CD1d have now been shown ...
Wilson IA +3 more
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