Results 221 to 230 of about 46,788 (276)

Expression of putative targets of immunotherapy in acute myeloid leukemia and healthy tissues [PDF]

, 2014
Barrett, A J, Battiwalla, M, Fathi, A T, Fraser, J W, Goswami, M, Hensel, N, Hourigan, C S, Ito, S, Jagasia, M, Jain, N A, Levis, M J, Levitsky, H I, Prince, G T, Qin, L, Rajkhowa, T, Sadrzadeh, H, Savani, B N, Smith, B D, Strickland, S A   +18 more
core   +1 more source

The Critical Role of APOE+ Macrophages in the Immune Microenvironment and Prognosis of Lung Adenocarcinoma

Journal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT The immunoregulatory functions and clinical implications of APOE+ macrophages within the tumour microenvironment of lung adenocarcinoma remain incompletely defined. In this study, single‐cell transcriptome analysis revealed distinct subsets of APOE+ macrophages, and subsequent CellChat analyses highlighted that these cells predominantly ...
Xiaofei Wang, Pengpeng Zhang, Wei Ye, Mingjun Du, Chenjun Huang, Jianan Zheng   +5 more
wiley   +1 more source

Chronic Lymphocytic Leukemia: Novel Therapeutic Targets Under Investigation. [PDF]

Cancers (Basel)
Nayyar M, Menezes RCB, Ailawadhi S, Parrondo RD.   +3 more
europepmc   +1 more source

Multiparametric Optimization of Human Primary B‐Cell Cultures Using Design of Experiments

Scandinavian Journal of Immunology, Volume 102, Issue 2, August 2025.
ABSTRACT B cells are essential in the immune system, driving antibody production, cytokine secretion and antigen presentation. Studies in mouse models have illuminated key mechanisms underlying B‐cell activation, differentiation, class‐switch recombination and somatic hypermutation. However, the extent to which these findings translate to human biology
Anne Bruun Rovsing, Kenneth Green, Lisbeth Jensen, Ian Helstrup Nielsen, Jacob Giehm Mikkelsen, Søren E. Degn   +5 more
wiley   +1 more source

Mature tertiary lymphoid structures linked to HPV status and anti-PD-1 based chemoimmunotherapy response in head and neck squamous cell carcinoma. [PDF]

Oncoimmunology
Zhang L, Ren S, Lan T, Marco V, Liu N, Wei B, Chen Y, Wu J, Li Q, Wu F, Lu P, Miao J, Lin H, Wang X, Zhong J, Li J, Fan S.   +16 more
europepmc   +1 more source

NKp30: A Key Membrane Molecule in the Fight Against Cancer and Infection

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
NKp30 is a crucial activating receptor on the surface of NK cells, mediating NK cell activation or the release of regulatory factors to exert cytotoxic effects by recognizing and binding to corresponding ligands. This article discusses the glycosylation of NKp30 and its pivotal role in antitumor and anti‐infection responses.
Yushu Shao, Yang Zhang, Jiaying Cao, Junyu He, Qian He, Yan Lei, Ning Tang, Yanhong Zhou   +7 more
wiley   +1 more source

Disease-specific signatures of circulating extracellular vesicles detected by the surface plasmon resonance imaging: a pilot study. [PDF]

Extracell Vesicles Circ Nucl Acids
Shibuta T, Takada Y, Nishinosono S, Yasuda S, Ono Y, Hirooka Y, Irikura D, Saito K, Umemura T.   +8 more
europepmc   +1 more source

Advancing Treatment in Pediatric Multiple Sclerosis: The Promise of B-Cell-Targeting Therapies. [PDF]

Int J Mol Sci
Skarlis C, Kotsari M, Anagnostouli M.
europepmc   +1 more source

Muscle Infiltration in Chronic Lymphocytic Leukemia: A Diagnostic Challenge. [PDF]

Diagnostics (Basel)
Ichikawa J, Kirito K, Kawasaki T, Onohara K, Wako M, Haro H.   +5 more
europepmc   +1 more source