Results 121 to 130 of about 139,688 (144)
Some of the next articles are maybe not open access.
Visualization of human helper T lymphocyte differentiation antigen in primate brain
Peptides, 1988The differentiation antigen T4 is present on the helper/inducer subset of T cells. In the acquired immune deficiency syndrome (AIDS), this lymphocyte subset is selectively depleted by HTLV-III/LAV virus which apparently uses the T4 antigen as a viral receptor.
Francis W. Ruscetti +3 more
openaire +3 more sources
Ultrastructure and differential antigens of human T-lymphocytes during embryogenesis
Bulletin of Experimental Biology and Medicine, 1979Thymocytes of human embryos at the 7–8-week stage have irregularly shaped nuclei with one to three distinct nucleoli, characterized by absence of compact chromatin or heterochromatin. The electron-dense cytoplasm of these cells contains polysomes and a few mitochondria.
I. I. Kalinina, S. S. Raitsina
openaire +2 more sources
Expression of Lymphocyte Differentiation Antigens in Immunodeficiency Diseases
1986Immunodeficiency diseases are frequently caused by defects in lymphocyte differentiation resulting in inadequate synthesis of immunoglobulin (Ig) or the lack of antigen-specific antibodies (1). The failure of B cells to differentiate into plasma cells results from either inherent B cell defects, the selective absence of helper T cell activity ...
Thomas F. Tedder +3 more
openaire +2 more sources
Immunochemical Characterization of a Human B Lymphocyte Differentiation Antigen (p65)
Scandinavian Journal of Immunology, 1980A human B‐cell differentiation antigen (BDA‐1) with a molecular weight of 65,000 was Identified by use of an anti‐B‐cell xenoantiserum. BDA‐1 was isolated by immunoprecipitation of cell lysates from a B‐lymphoblastoid cell line (SB) and from blood B lymphocytes (sIg+ER−) of four normal individuals.
Soldano Ferrone +4 more
openaire +3 more sources
Biochemical Analysis of Human T Lymphocyte Differentiation Antigens T4 and T5
Science, 1980Two major functionally distinct T cell subsets in man have been defined with heteroantiserums and monoclonal antibodies directed against stable cell surface antigens that appear during thymic ontogeny. A monoclonal antibody to T4 antigen (anti-T4) is reactive with the peripheral inducer T cell population while a monoclonal antibody to T5 antigen (anti ...
Cox Terhorst +3 more
openaire +2 more sources
INDUCTION OF HUMAN T-LYMPHOCYTE DIFFERENTIATION ANTIGENS
1976Publisher Summary This chapter presents a summarization of the results of an analysis of human T-lymphocyte differentiation antigens (HTLAs) demonstrating the existence of human T-lymphocyte differentiation antigens, their induction on precursor cells by thymic factors, and the application of this methodology to the investigation of immunodeficiency ...
openaire +2 more sources
Journal of Interferon Research, 1985
Macrophage-T-lymphocyte cultures from patients with recent recurrent herpes labialis were stimulated to produce gamma interferon by either herpes simplex antigen or mitogens (PHA and Con A). The ability of monoclonal antibodies to HLA-DR and DC/DS, HSV glycoprotein antigens and T-lymphocyte surface antigens to inhibit interferon production and ...
Teresa Y. Basham +3 more
openaire +3 more sources
Macrophage-T-lymphocyte cultures from patients with recent recurrent herpes labialis were stimulated to produce gamma interferon by either herpes simplex antigen or mitogens (PHA and Con A). The ability of monoclonal antibodies to HLA-DR and DC/DS, HSV glycoprotein antigens and T-lymphocyte surface antigens to inhibit interferon production and ...
Teresa Y. Basham +3 more
openaire +3 more sources
Scandinavian Journal of Immunology, 1988
Graft‐versus‐host disease (GVHD) after allogeneic hone marrow transplantation (BMT) is initiated by immunocompetent T fells present in the graft. Selective elimination of distinct T‐cell subsets or a sufficient, but not complete T‐cell depletion, might abolish severe GVHD without graft rejection and loss of the anti‐tumour potential.
Wil J.M. Tax +6 more
openaire +3 more sources
Graft‐versus‐host disease (GVHD) after allogeneic hone marrow transplantation (BMT) is initiated by immunocompetent T fells present in the graft. Selective elimination of distinct T‐cell subsets or a sufficient, but not complete T‐cell depletion, might abolish severe GVHD without graft rejection and loss of the anti‐tumour potential.
Wil J.M. Tax +6 more
openaire +3 more sources
Nature, 1980
During embryogenesis, stem cells migrate from the bloodstream into the thymic rudiment where they proliferate and differentiate into T lymphocytes. The epithelial cells of the thymic stroma may influence these processes by providing hormonal and/or contact stimuli to the developing lymphoblasts.
Jenkinson, E J, Owen, J J, Aspinall, R
openaire +3 more sources
During embryogenesis, stem cells migrate from the bloodstream into the thymic rudiment where they proliferate and differentiate into T lymphocytes. The epithelial cells of the thymic stroma may influence these processes by providing hormonal and/or contact stimuli to the developing lymphoblasts.
Jenkinson, E J, Owen, J J, Aspinall, R
openaire +3 more sources
Modulation of Cell Membrane Antigens during Differentiation of Rat T-Lymphocytes
1979The aim of the experiments presented here was to trace the differentiation pathway of thymic lymphocytes to peripheral T-lymphocytes in serological and molecular terms. For this purpose the rat has the advantage over the mouse that in this species that antigenic structure being the predominating one on the surface membrane of thymus lymphocytes i.e ...
R. Arndt +2 more
openaire +3 more sources