Results 71 to 80 of about 99,037 (313)

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian   +5 more
wiley   +1 more source

Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke

open access: yesStem Cells International, 2016
Currently, there is increasing interest in human bone marrow stromal cells (hBMSCs) as regeneration therapy against cerebral stroke. The aim of the present study was to evaluate the feasibility and validity of hBMSC cultures with allogeneic platelet ...
Chengbo Tan   +10 more
doaj   +1 more source

Hepatic stellate cells and parasite-induced liver fibrosis [PDF]

open access: yes, 2010
: Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT   +3 more
core   +2 more sources

Allele frequencies of Human Platelet Antigen 1 and Human Platelet Antigen 5 in the Maltese

open access: yes, 2021
Background: The human platelet antigen systems consist of antigenic polymorphisms that arise from single base pair substitutions leading to amino acid changes in platelet glycoproteins. These polymorphisms cause a variety of clinically significant conditions where platelet typing is essential for accurate diagnosis and subsequent treatment.
Falzon Lia, Martina   +2 more
openaire   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee   +9 more
wiley   +1 more source

The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis [PDF]

open access: yes, 2011
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial ...
Antunes, RF, Dumitriu, IE, Kaski, JC
core   +3 more sources

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Genetic restriction of humoral immune response

open access: yesОнкогематология, 2014
The review provides information about immune response initiation against foreign agents. Significance of separate molecules of major histocompatibility complex in antibodies formation after blood transfusion, during pregnancy, after organ transplantation
L. L. Golovkina
doaj   +3 more sources

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

Efektivitas Transfusi Trombosit Hasil Uji Silang Serasi (Crossmatch) pada Kondisi Trombositopenia Refrakter

open access: yesSari Pediatri, 2018
Latar belakang. Penyebab imun tersering trombositopenia refrakter adalah adanya antibodi terhadap human leukocyte antigens (HLA) dan atau human platelet antigens (HPA).
Murti Andriastuti   +2 more
doaj   +1 more source

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