Results 21 to 30 of about 12,887 (114)

Characterization of the Fine Specificity of Bovine CD8 T-Cell Responses to Defined Antigens from the Protozoan ParasiteTheileria parva [PDF]

Infection and Immunity, 2008
ABSTRACTImmunity against the bovine intracellular protozoan parasiteTheileria parvahas been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells fromT. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of developing a subunit vaccine.
Graham, SP, Pellé, R, Yamage, M, Mwangi, DM, Honda, Y, Mwakubambanya, RS, de Villiers, EP, Abuya, E, Awino, E, Gachanja, J, Mbwika, F, Muthiani, AM, Muriuki, C, Nyanjui, JK, Onono, FO, Osaso, J, Riitho, V, Saya, RM, Ellis, SA, McKeever, DJ, MacHugh, ND, Gilbert, SC, Audonnet, JC, Morrison, WI, van der, Bruggen P, Taracha, EL   +25 more
openaire   +6 more sources

Inhibitory effects on protein kinase C activity by lipophosphoglycan fragments and glycosylphosphatidylinositol antigens of the protozoan parasite Leishmania [PDF]

Biochemical Journal, 1989
Fragments of the lipophosphoglycan of Leishmania donovani were generated by phospholipase C digestion and mild acid hydrolysis. The fragments were purified and examined for inhibitory activity on protein kinase C isolated from rat brains. On a molar basis, the 1-O-alkylglycerol portion of LPG exhibited the most inhibitory activity, whereas the ...
M V Londner, Tessie B. McNeely, Salvatore J. Turco, G Rosen   +3 more
openaire   +3 more sources

The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]

, 2019
Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto, Bivona, Augusto Ernesto, Cardoso Landaburu, Alejandro Cesar, Cazorla, Silvia Ines, Cerny, Natacha, Czentner Colomo, Lucas, Estevez, José Octavio, Malchiodi, Emilio Luis, Marco, Jorge Diego, Nevot, María Cecilia, Sanchez Alberti, Andrés   +10 more
core   +1 more source

Evolution and diversity of secretome genes in the apicomplexan parasite Theileria annulata [PDF]

, 2010
<b>BACKGROUND</b>: Little is known about how apicomplexan parasites have evolved to infect different host species and cell types. Theileria annulata and Theileria parva invade and transform bovine leukocytes but each species favours a ...
Baird, M., Karagenç, T., Shiels, B.R., Tait, A., Weir, W.   +4 more
core   +4 more sources

Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle [PDF]

, 2017
Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp.
Blake, D P, Crouch, C, Long, E, Marugan-Hernandez, V, Tomley, F M   +4 more
core   +1 more source

The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates [PDF]

, 2017
Vaccine development targeting protozoan parasites remains challenging, partly due to the complex interactions between these eukaryotes and the host immune system.
Aliaga-Leyton, Altenhoff, Anja Joachim, Aruna Shrestha, Bhopale, Blake, Blake, Blum, Bradford, Burset, Bärbel Ruttkowski, Cantarel, Claus Vogl, Conesa, Cui, Damer P. Blake, de Oliveira Lopes, Dlugonska, Elsheikha, Emanuelsson, Fiona Tomley, Flower, Gabner, Gajria, Gharahdaghi, Goodswen, Goodswen, Goodswen, Goodswen, Hassan, Hehl, Hiszczynska-Sawicka, Horton, Jackson, Jenkins, Jimenez, Joachim, Jones, Jongert, Kall, Kim, Kissinger, Korf, Kurtz, Larsen, Lillehoj, Lim, Lindsay, Loytynoja, Martens, Matrajt, McAllister, Meyer, Min, Monney, Monney, Mortazavi, Mundt, Myhre, Nam, Nicola Palmieri, Nishikawa, Ogedengbe, Parra, Petersen, Pizza, Ramaprasad, Reichel, Samarasinghe, Sato, Schulz, Schwarz, Schwarz, Shevchenko, Shrestha, Sonnhammer, Stanisic, Stanke, Stephen, Templeton, Thorvaldsdottir, Tomas Beck, Trapnell, Williams, Worliczek, Worliczek, Worliczek, Xiang, Zhu   +88 more
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Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci [PDF]

, 2020
Theileria parva is a tick‐transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa.
Ahmed, Jabbar, Bishop, Richard P., Clausen, Peter‐Henning, Kabi, Fredrick, Kasaija, Paul, Lubega, George W., Mwega, Elisa, Nanteza, Anne, Njahira, Moses, Njuguna, Joyce, Obara, Isaiah, Odongo, David, Salih, Diaeldin A., Skilton, Rob A.   +13 more
core   +1 more source

A perspective on clonal phenotypic (antigenic) variation in protozoan parasites

Parasitology, 2002
Intra-clonal phenotypic (antigenic) variation is used by many pathogens to evade the consequences of immune-mediated killing by mammalian hosts. In this substantially theoretical article, I emphasise that antigenic variation (sensu stricto) involves no change in genotype; its importance as a mechanism for promoting pathogen transmission and its ...
openaire   +3 more sources

Environmental transmission of Toxoplasma gondii: Oocysts in water, soil and food [PDF]

, 2019
Toxoplasma gondii is a zoonotic protozoan parasite that can cause morbidity and mortality in humans, domestic animals, and terrestrial and aquatic wildlife. The environmentally robust oocyst stage of T.
Bahia-Oliveira, Lillian, de Wit, Luz A., Dixon, Brent, Dumètre, Aurélien, Shapiro, Karen, VanWormer, Elizabeth, Villena, Isabelle   +6 more
core   +4 more sources

Development and Validation of In‐House Conventional and Multiplex PCR Methods for the Detection and Identification of Lophomonas spp.: An Innovative Approach

Journal of Clinical Laboratory Analysis, EarlyView.
Sequence alignment of the SSU rRNA of the two Lophomonas species, L. blattarum and L. striata. The red rectangle highlights the position of the reverse universal primer; the yellow, the L. blattarum‐specific forward primer; and the green, the L. striata‐specific forward primer used in multiplex PCR.
Maryam Nakhaei, Mahdi Fakhar, Abouzar Bagheri, Hajar Ziaei Hezarjaribi, Saied Abediankenari, Ali Sharifpour, Maryam Ghasemi   +6 more
wiley   +1 more source