Results 91 to 100 of about 44,256 (203)

Invasive breast cancer in Argentine women: association between risk and prognostic factors with antigens of a peptidic and carbohydrate nature

Breast Cancer: Targets and Therapy, 2011
Sandra O Demichelis, Marina T Isla-Larrain, Luciano Cermignani, Cecilio G Alberdi, Amada Segal-Eiras, María Virginia CroceCentre of Basic and Applied Immunological Research, Faculty of Medical Sciences, National University of La Plata, La ...
Croce MV, Segal-Eiras A, Alberdi CG, Cermignani L, Isla-Larrain MT, Demichelis SO   +5 more
doaj  

Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

BMC Cancer, 2018
Background Glycosylation plays a critical role in the aggressiveness of pancreatic cancer (PC). Emerging evidences indicate significant involvement of cancer stem cells (CSCs) in PC aggressiveness.
Srikanth Barkeer, Seema Chugh, Saswati Karmakar, Garima Kaushik, Sanchita Rauth, Satyanarayana Rachagani, Surinder K. Batra, Moorthy P. Ponnusamy   +7 more
doaj   +1 more source

Radioimmunologic Methods for Diagnosis of Malignant Diseases [PDF]

, 1975
The recent availability of the carcinoembryonic antigen (CEA) assay has stimulated great clinical interest in tumor antigens. Carcinoembryonic antigen is not the only specific or tumor-associated antigen currently identified.
Hoffer, Paul B.
core   +1 more source

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]

, 2002
The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Dvorankova, Barbora, Gabius, Hans-Joachim, Hercogová, Jana, Holíkova, Zuzana, Kaltner, Herbert, Motlik, Jan, Plzák, Jan, Smetana, Karel   +7 more
core   +1 more source

Liposomes and nanotechnology in drug development: focus on oncotargets

International Journal of Nanomedicine, 2012
Tomohiro Kozako,1 Naomichi Arima,2 Makoto Yoshimitsu,3 Shin-Ichro Honda,1 Shinji Soeda11Department of Biochemistry, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; 2Division of Hematology and Immunology, Center for Chronic Viral ...
Kozako T, Arima N, Yoshimitsu M, Honda S-I, Soeda S   +4 more
doaj  

Carbohydrate moieties of major histocompatibility complex class I alloantigens are not required for their recognition by T lymphocytes. [PDF]

, 1985
The ability to generate specific cytotoxic responses using purified major histocompatibility complex (MHC) antigen in liposomes has made it possible to directly assess the importance of class I carbohydrate moieties in T cell recognition of alloantigen ...
Goldstein, SA, Mescher, MF
core  

Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. [PDF]

, 2019
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Chen, Xi, Kooner, Anoopjit Singh, Yu, Hai   +2 more
core   +2 more sources

Ovarian Carcinoma and Serous Effusions. Changing Views Regarding Tumor Progression and Review of Current Literature1

Analytical Cellular Pathology, 2001
Carcinoma of the ovary is the leading cause of death from gynecological cancer in western countries. Ovarian carcinoma is commonly associated with the accumulation of fluid containing malignant cells in the peritoneal, and not infrequently in the pleural
Ben Davidson
doaj   +1 more source

Anomerization of N-Acetylglucosamine Glycosides Promoted by Dibromomethane and Dimethylformamide

Molecules
In previous quests to synthesize fragments of tumor-associated carbohydrate antigens (TACAs), we determined that bromoalkyl β glycosides of N-acetylglucosamine were labile and incompatible with some of the synthetic conditions required for the ...
Natalie B. Condino, Doriane Rousseau, Esperance Mutoni, Jeffrey Davidson, Lara K. Watanabe, France-Isabelle Auzanneau   +5 more
doaj   +1 more source

The Glycopeptide PV-PS A1 Immunogen Elicits Both CD4+ and CD8+ Responses

Vaccines
Background/Objectives: The MHCII-dependent, CD4+ T-cell zwitterionic polysaccharide PS A1 has been investigated as a promising carrier for vaccine development because it can induce an MHCII-dependent CD4+ response towards a variety of tumor-associated ...
Sharmeen Nishat, Md Kamal Hossain, Geraud Valentin, Farzana Hossain, Shanika Gamage, Katherine A. Wall, Peter R. Andreana   +6 more
doaj   +1 more source