Results 71 to 80 of about 9,201,478 (158)

Engineering the tumor microenvironment of colorectal cancer [PDF]

, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

Chemoenzymatic synthesis of derivatives of a T-cell-stimulating peptide which carry tumor-associated carbohydrate antigens

, 2001
The Tn (GalNAc-Ser/Thr), T [Gal(13)GalNAc-Ser/Thr], sialyl-Tn [Neu5Ac(26)GalNAc-Ser/Thr] and 2,3-sialyl-T [Neu5Ac(23)Gal(13)GalNAc-Ser/Thr] antigens are examples of tumor-associated carbohydrate antigens expressed by epithelial cancers.
George, Shaji K, Reis, Celso A, Schwientek, Tilo, Clausen, Henrik, Kihlberg, Jan,, Holm, Björn,   +5 more
core   +1 more source

Invasive breast cancer in Argentine women: association between risk and prognostic factors with antigens of a peptidic and carbohydrate nature

Breast Cancer: Targets and Therapy, 2011
Sandra O Demichelis, Marina T Isla-Larrain, Luciano Cermignani, Cecilio G Alberdi, Amada Segal-Eiras, María Virginia CroceCentre of Basic and Applied Immunological Research, Faculty of Medical Sciences, National University of La Plata, La ...
Croce MV, Segal-Eiras A, Alberdi CG, Cermignani L, Isla-Larrain MT, Demichelis SO   +5 more
doaj  

Investigating the potential of the Metastasis Associated Antigen 1 (MTA1) for cancer immunotherapy in a murine model [PDF]

, 2007
Immunotherapeutic approaches to target antigens associated with metastasis could provide a valuable means of targeting metastatic cells specifically. Metastasis Associated Antigen (MTA1) is one such relatively novel antigen, which has been associated ...
Assudani, D
core  

Promising tumor-associated antigens for future prostate cancer therapy

, 2010
Prostate cancer (CaP) is one of the most prevalent malignant diseases among men in Western countries. There is currently no cure for metastatic castrate-resistant CaP, and median survival for these patients is about 18 months; the high mortality rate ...
Cozzi, Paul, Russell, Pamela, Li, Yong, Russell, Pamela J., Cozzi, Paul J.   +4 more
core   +1 more source

Animal lectins as cell adhesion molecules [PDF]

, 1998
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core   +1 more source

Marcadores tumorais em pacientes com artrite reumatóide [PDF]

, 2010
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Bergamaschi, Samuel Brighenti
core  

Evidence for Two Populated Conformations for the Dimeric LeX and LeALeX Tumor-Associated Carbohydrate Antigens [PDF]

, 2014
The conformational behavior of tumor associated carbohydrate antigens (TACAs) dimLex and LeaLex was studied using a combination of NMR experiments and molecular dynamic simulations.
Jackson, Trudy A., Auzanneau, France-Isabelle, Valerie Robertson, France-Isabelle Auzanneau, Trudy A. Jackson, Robertson, Valerie   +5 more
core   +1 more source

Liposomes and nanotechnology in drug development: focus on oncotargets

International Journal of Nanomedicine, 2012
Tomohiro Kozako,1 Naomichi Arima,2 Makoto Yoshimitsu,3 Shin-Ichro Honda,1 Shinji Soeda11Department of Biochemistry, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; 2Division of Hematology and Immunology, Center for Chronic Viral ...
Kozako T, Arima N, Yoshimitsu M, Honda S-I, Soeda S   +4 more
doaj  

Maternal Tn Immunization Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats Through Suppression of Oxidative Stress and Inflammation

Frontiers in Immunology, 2019
Hyperoxia therapy is often required to treat newborns with respiratory disorders. Prolonged hyperoxia exposure increases oxidative stress and arrests alveolar development in newborn rats.
Chung-Ming Chen, Chung-Ming Chen, Jaulang Hwang, Hsiu-Chu Chou   +3 more
doaj   +1 more source