Results 101 to 110 of about 44,256 (203)

Differential expression of CD175 and CA19-9 in pancreatic adenocarcinoma

Scientific Reports
Alterations in protein glycosylation are observed in many solid tumor types leading to formation of tumor-associated carbohydrate antigens (TACAs). The most common TACA is the Tn antigen (CD175), which is a mucin-type O-GalNAc-Ser/Thr/Tyr glycan in ...
Jane J. Cheng, Yasuyuki Matsumoto, Gabrielle E. Dombek, Kathryn A. Stackhouse, Ana Sofia Ore, Jonathan N. Glickman, Jamie Heimburg-Molinaro, Richard D. Cummings   +7 more
doaj   +1 more source

Preclinical evaluation of glycan-targeting monoclonal antibodies for bimodal near-infrared fluorescence and photoacoustic imaging of gastrointestinal cancers

EJNMMI Research
Background Near-infrared fluorescence (NIRF) imaging assists surgeons intraoperatively to achieve radical resection of malignant tissue with one centimeter depth and can be supplemented with photoacoustic imaging to increase depth-of-view.
Ruben D. Houvast, Vincent Q. Sier, Maurice van Duijvenvoorde, Victor M. Baart, Timo Schomann, JiaXin Chua, Mireille Vankemmelbeke, Lindy G. Durrant, Daniëlle Krijgsman, Pieter de Heer, Gert-Jan Hassing, J. Sven D. Mieog, A. Stijn L. P. Crobach, Jacobus Burggraaf, Peter J.K. Kuppen, Alexander L. Vahrmeijer, Cornelis F. M. Sier   +16 more
doaj   +1 more source

Glycomics in Human Diseases and Its Emerging Role in Biomarker Discovery

Biomedicines
Glycosylation, the enzymatic addition of glycans to proteins and lipids, is a critical post-translational modification that influences protein folding, stability, trafficking, immune modulation, and cell signaling.
Sherifdeen Onigbinde, Moyinoluwa Adeniyi, Oluwatosin Daramola, Favour Chukwubueze, Md Mostofa Al Amin Bhuiyan, Judith Nwaiwu, Tuli Bhattacharjee, Yehia Mechref   +7 more
doaj   +1 more source

Novel Techniques and Their Applications to Health Foods, Agricultural and Medical Biotechnology: Functional Genomics and Basic Epigenetic Controls in Plant and Animal Cells [PDF]

, 2004
Selected applications of novel techniques for analyzing Health Food formulations, as well as for advanced investigations in Agricultural and Medical Biotechnology aimed at defining the multiple connections between functional genomics and epigenomic ...
Baianu, I.C., Lin, H.C., Lozano, P., Prisecaru, V. I.   +3 more
core  

Unraveling the role of C1GALT1 in abnormal glycosylation and colorectal cancer progression

Frontiers in Oncology
C1GALT1 plays a pivotal role in colorectal cancer (CRC) development and progression through its involvement in various molecular mechanisms. This enzyme is central to the O-glycosylation process, producing tumor-associated carbohydrate antigens (TACA ...
Hong Tian, Jia-Li Yu, Xiaoli Chu, Qi Guan, Juan Liu, Ying Liu   +5 more
doaj   +1 more source

Improving cellular cancer vaccines [PDF]

, 2010
Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
core   +1 more source

A correlation study of serum tumor markers with systemic lupus erythematosus-associated interstitial lung disease

Frontiers in Medicine
BackgroundSystemic lupus erythematosus-associated interstitial lung disease (SLE-ILD) is a pulmonary manifestation of SLE. Currently, serum biomarkers for early identification of SLE-ILD are lacking.
Xing He, Xing He, Jiaqi Ji, Ting Zhou, Zeli Luo, Siyu Fang, Xixi Chen, Chi Liu, Haiying Yan, Lu Guo   +9 more
doaj   +1 more source

Synergistic Association of Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 on the Risk of Abnormal Glucose Regulation

Diabetes, Metabolic Syndrome and Obesity, 2020
Yu-Cheng Cheng,1 Yu-Hsuan Li,1,2 Chiann-Yi Hsu,3 I-Te Lee1,4– 6 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; 2Graduate Institute of Data Science, Taipei Medical ...
Cheng YC, Li YH, Hsu CY, Lee IT
doaj  

Glucocorticoid-regulated localization of cell surface glycoproteins in rat hepatoma cells is mediated within the Golgi complex. [PDF]

, 1988
Glucocorticoid hormones regulate the post-translational maturation and sorting of cell surface and extracellular mouse mammary tumor virus (MMTV) glycoproteins in M1.54 cells, a stably infected rat hepatoma cell line.
APONTE, Gregory W., Bravo, D, Firestone, G, Haffar, O, Hess, R, John, N   +5 more
core   +1 more source

Tumor Associated Carbohydrate Antigens in Targeted Therapy [PDF]

Postdoc Journal, 2016
openaire   +1 more source