Results 11 to 20 of about 17,759 (207)

Interplay of non-coding RNAs and approved antimetabolites such as gemcitabine and pemetrexed in mesothelioma

open access: yesNon-coding RNA Research, 2018
Gemcitabine and pemetrexed are clinically approved antimetabolites for the therapy of mesothelioma diseases. These drugs are often applied in combination with platinum complexes and other drugs.
Bernhard Biersack
doaj   +2 more sources

Risk of failing both methotrexate and mycophenolate mofetil from the First-line Antimetabolites as Steroid-sparing Treatment (FAST) uveitis trial [PDF]

open access: yesJournal of Ophthalmic Inflammation and Infection, 2023
Background The antimetabolites methotrexate (MTX) and mycophenolate mofetil (MMF) are commonly used as initial corticosteroid-sparing treatment for uveitis. There is little data examining risk factors for failing both MTX and MMF.
Amit K. Reddy   +15 more
doaj   +2 more sources

Steroidal Antimetabolites Protect Mice against Trypanosoma brucei

open access: yesMolecules, 2022
Trypanosoma brucei, the causative agent for human African trypanosomiasis, is an emerging ergosterol-dependent parasite that produces chokepoint enzymes, sterol methyltransferases (SMT), not synthesized in their animal hosts that can regulate cell ...
Minu Chaudhuri   +4 more
doaj   +2 more sources

Long-term follow-up of trabeculectomy without antimetabolites in patients with uveitis

open access: yes, 1999
To determine the long-term success rate after trabeculectomy without antimetabolites in patients with ...
Stavrou, P, Murray, P I; id_orcid
core   +6 more sources

Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists [PDF]

open access: yes, 2014
AIMS: To investigate whether drugs others than mycophenolic acid and ipilimumab might cause graft-versus-host-like apoptotic enteropathy, the clinicopathological findings in four patients were examined who had developed watery diarrhoea and apoptotic ...
Rogler, Gerhard   +6 more
core   +2 more sources

Synthesis, Antitumor and Antiviral In Vitro Activities of New Benzotriazole-Dicarboxamide Derivatives

open access: yesFrontiers in Chemistry, 2021
Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba   +10 more
doaj   +1 more source

An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil’s Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer

open access: yesMolecules, 2023
Antimetabolites, especially 5-fluorouracil, are commonly used clinically to treat breast, colon, and other cancers. However, their side effects and inefficiency in monotherapy have prompted further searches for new combinations.
Małgorzata Milczarek   +7 more
doaj   +1 more source

Comparison of remdesivir and favipiravir - the anti-Covid-19 agents mimicking purine RNA constituents

open access: yesBiomedical Papers, 2022
By December 2019, humanity was challenged by a new infectious respiratory disease named coronavirus disease of 2019 or COVID-19. This is a viral infection based on the presence of the previously non-problematic coronavirus with assigned number 2.
Faiha M. Al-Ardhi   +3 more
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

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