Results 21 to 30 of about 17,759 (207)

Modern Methods of Controlling Wound Healing after Fistulizing Glaucoma Surgery. Risk Factors and Antimetabolites

open access: yesOftalʹmologiâ, 2017
The article describes modern approaches to controlling wound healing after fistulizing glaucoma surgery. It provides a classification of refractory glaucoma degrees and summarizes risk factors for excessive scarring. Author describes various applications
S. Yu. Petrov
doaj   +1 more source

Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction [PDF]

open access: yes, 2020
Background: Nasolacrimal duct obstruction (NLDO) is a condition that results in the overflow of tears (epiphora) or infection of the nasolacrimal sac (dacryocystitis).
Dinesh Selva   +9 more
core   +1 more source

Identification of anticancer drugs for hepatocellular carcinoma through personalized genome‐scale metabolic modeling

open access: yesMolecular Systems Biology, 2014
Genome‐scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype–phenotype relationship in a mechanistic manner.
Rasmus Agren   +5 more
doaj   +1 more source

Cancer Metabolism and Drug Resistance

open access: yesMetabolites, 2015
Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be associated with the etiology of cancer. Furthermore, accumulating evidence suggest that cancer metabolism is intimately linked to drug resistance, which is ...
Mahbuba Rahman, Mohammad Rubayet Hasan
doaj   +1 more source

Variation of Cost among Anti-cancer Drugs Available in Indian Market [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Although cancer remains a major health problem all over the world, its treatment is limited by affordability of patients in a developing country like India.
Bhanu Prakash Kolasani   +2 more
doaj   +1 more source

New Steroidal Selenides as Proapoptotic Factors

open access: yesMolecules, 2023
Cytostatic and pro-apoptotic effects of selenium steroid derivatives against HeLa cells were determined. The highest cytostatic activity was shown by derivative 4 (GI50 25.0 µM, almost complete growth inhibition after three days of culture, and over 97 ...
Izabella Jastrzebska   +7 more
doaj   +1 more source

Xeloda as first-line therapy of metastatic colorectal cancer-our experience [PDF]

open access: yesArchive of Oncology, 2002
BACKGROUND: Results of phase III clinical studies comparing efficacy of Xeloda vs. standard 5-FU/FA protocols as first line therapy of metastatic colorectal carcinoma (MCRC), have shown better efficacy of Xeloda, with less toxic adverse effects, apart ...
Kovčin Vladimir   +4 more
doaj   +1 more source

Antimicrobial Peptide Induced-Stress Renders Staphylococcus aureus Susceptible to Toxic Nucleoside Analogs

open access: yesFrontiers in Immunology, 2020
Cationic antimicrobial peptides (AMPs) are active immune effectors of multicellular organisms and are also considered as new antimicrobial drug candidates.
Alexandro Rodríguez-Rojas   +8 more
doaj   +1 more source

Adenosine kinase of Trypanosoma brucei and its role in susceptibility to adenosine antimetabolites

open access: yes, 2007
Trypanosoma brucei cannot synthesize purines de novo and relies on purine salvage from its hosts to build nucleic acids. With adenosine being a preferred purine source of bloodstream-form trypanosomes, adenosine kinase (AK; EC 2.7.1.20) is likely to be a
Önal, Pinar   +3 more
core   +1 more source

Vascular Acrosyndromes Associated With Prolonged Tumor Response in Advanced Lung Cancer Patients During Treatment With Antimetabolites: A Report of Two Cases

open access: yesFrontiers in Oncology, 2021
BackgroundPemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However, rare vascular side effects can occur such as vascular acrosyndromes and especially
Margaux Geier   +6 more
doaj   +1 more source

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