Results 11 to 20 of about 32,473 (237)

The Metabolomic Profile of the Essential Oil from Zanthoxylum caribaeum (syn. chiloperone) Growing in Guadeloupe FWI using GC × GC-TOFMS

Metabolites, 2022
The essential oil (EO) from the leaves of Zanthoxylum caribaeum (syn. Chiloperone) (Rutaceae) was studied previously for its acaricidal, antimicrobial, antioxidant, and insecticidal properties.
Lea Farouil, Ryan P. Dias, Gianni Popotte-Julisson, Garrick Bibian, Ahissan Innocent Adou, A. Paulina de la Mata, Muriel Sylvestre, James J. Harynuk, Gerardo Cebrián-Torrejón   +8 more
doaj   +1 more source

Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics. [PDF]

Asia Pac J Clin Oncol
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Pan M, Sun J, Kawashima M, Kim YC, Chun M, Chu CY, Liang YH, Chang M, Kerob D, Dreno B.   +9 more
europepmc   +2 more sources

Cardiotoxic effects induced by the use of antimetabolites in the chemotherapy of oncological diseases

КардиоСоматика, 2021
In modern medical practice, the treatment of cancer is one of the most pressing issues. Many of the drugs used in the treatment of cancer have a toxic effect on the cardiovascular system of patients. The main clinical manifestations of cardiotoxicity are
Alina A. Aliab'eva, Galina S. Mal
doaj   +1 more source

A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites

Nature Communications, 2020
Stress response pathways are critical for cellular homeostasis, promoting survival through adaptive changes in gene expression and metabolism. They play key roles in numerous diseases and are implicated in cancer progression and chemoresistance. However,
Stefan Reich, Chi D. L. Nguyen, Canan Has, Sascha Steltgens, H. Soni, C. Coman, Moritz Freyberg, Anna Bichler, Nicole Seifert, Dominik Conrad, Christiane B. Knobbe-Thomsen, Björn Tews, G. Toedt, R. Ahrends, Jan Medenbach   +14 more
semanticscholar   +1 more source

Practical approach to monitoring and prevention of infectious complications associated with systemic corticosteroids, antimetabolites, cyclosporine, and cyclophosphamide in nonmalignant hematologic diseases.

Hematology. American Society of Hematology. Education Program, 2020
Corticosteroids constitute a first-line therapy for adults and children suffering from nonmalignant immune-mediated hematologic diseases. However, high disease relapse rates during the tapering period or upon drug discontinuation result in long-term ...
L. Malpica, S. Moll
semanticscholar   +1 more source

Patterns of conjunctival and scleral regeneration after intraoperative application of cyclosporin A solution in rabbits with steroid-induced glaucoma

Бюллетень сибирской медицины, 2021
Aim. In an in vivo experiment, to study the effect of local intraoperative application of 0.05% cyclosporin A solution on the conjunctival and scleral regeneration after surgery on the rabbit eyes with steroid-induced  glaucoma.Materials and methods.
T. A. Zhigalskiaya, A. N. Dzyman, A. A. Krylova, O. I. Krivosheina, I. A. Khlusov   +4 more
doaj   +1 more source

Pathophysiological mechanisms of cardiotoxicity in chemotherapeutic agents

Russian Open Medical Journal, 2020
Certain success has been achieved in the treatment of cancer due to the development of various effective chemotherapeutic drugs. However, an increase in their effectiveness (aggressiveness) was associated with a growth of undesirable effects on the ...
Aleksey M. Chaulin, Olga E. Abashina, Dmitry V. Duplyakov   +2 more
doaj   +1 more source

Synthesis, Antitumor and Antiviral In Vitro Activities of New Benzotriazole-Dicarboxamide Derivatives

Frontiers in Chemistry, 2021
Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba, Sandra Piras, Paola Corona, Federico Riu, Roberta Loddo, Ilenia Delogu, Gabriella Collu, Giuseppina Sanna, Paola Caria, Tinuccia Dettori, Antonio Carta   +10 more
doaj   +1 more source

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapyinduced leukemia [PDF]

, 2001
Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens.
Allan, J.M., Wild, C.P., Rollinson, S., Willett, E.V., Moorman, A.V., Dovey, G.J., Roddam, P.L., Roman, E., Cartwright, R.A., Morgan, G.J.   +9 more
core   +7 more sources

An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil’s Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer

Molecules, 2023
Antimetabolites, especially 5-fluorouracil, are commonly used clinically to treat breast, colon, and other cancers. However, their side effects and inefficiency in monotherapy have prompted further searches for new combinations.
Małgorzata Milczarek, Tomasz Cierpiał, Piotr Kiełbasiński, Milena Małecka-Giełdowska, Marta Świtalska, Joanna Wietrzyk, Maciej Mazur, Katarzyna Wiktorska   +7 more
doaj   +1 more source