Results 81 to 90 of about 21,202 (267)

Screening antimycobacterial activity of Baccharis dracunculifolia, Centella asiatica, Lantana camara and Pterodon emarginatus

Revista Brasileira de Plantas Medicinais, 2015
The permanent investigation of new antimycobacterial drugs is necessary for the eradication programs of tuberculosis and other mycobacterium-related diseases.
R.R.P. MACHADO, R.C. DUTRA, F. PITTELLA, N.R.B. RAPOSO, B. LESCHE, R.S. DUARTE, G.L.G. SOARES, M.A.C. KAPLAN   +7 more
doaj   +1 more source

In-silico and in-vitro assessments of some fabaceae, rhamnaceae, apocynaceae, and anacardiaceae species against Mycobacterium tuberculosis H37Rv and triple-negative breast cancer cells

BMC Complementary Medicine and Therapies, 2023
Medicinal plants play a huge role in the treatment of various diseases in the Limpopo province (South Africa). Traditionally, concoctions used for treating tuberculosis and cancer are sometimes prepared from plant parts naturally occurring in the region,
Kudakwashe Nyambo, Francis Adu-Amankwaah, Kudzanai Ian Tapfuma, Lucinda Baatjies, Lauren Julius, Liezel Smith, Mkhuseli Ngxande, Krishna Govender, Lawrence Mabasa, Afsatou Traore, Maano Valerie Masiphephethu, Idah Sithole Niang, Vuyo Mavumengwana   +12 more
doaj   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source

Dynamics of cytokine profile indexes in children with first diagnosed pulmonary tuberculosis in the course of antimycobacterial therapy

Zaporožskij Medicinskij Žurnal, 2018
Antimycobacterial therapy is the main method of tuberculosis treatment. But some antimycobacterial medications have an unfavorable influence on the immune system and this fact significantly decreases efficiency of treatment and requires an additional ...
O. M. Raznatovska, Yu. V. Mironchuk
doaj   +1 more source

Medications Used Among Nonhospitalized Pregnant Women With COVID‐19: A Prospective Individual Patient Data Meta‐Analysis in Europe and North America

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 1, January 2026.
ABSTRACT Aim To estimate the prevalence of medication use in nonhospitalized pregnant women with COVID‐19. Methods A prospective two‐stage individual patient meta‐analysis across 10 data sources in Europe and North America studied medication use among nonhospitalized pregnant women with COVID‐19 between January 2020 and December 2022.
Odette de Bruin, Emeline Maisonneuve, Eimir Hurley, Hedvig M. E. Nordeng, Anick Bérard, Odile Sheehy, Padma Kaul, Mayura U. Shinde, Austin Cosgrove, Jennifer G. Lyons, Elizabeth Messenger‐Jones, Maria E. Kempner, Sengwee Toh, Wei Hua, José J. Hernández‐Muñoz, Leyla Sahin, Carolyn E. Cesta, David Hägg, Rosa Gini, Olga Paoletti, Beatriz Poblador‐Plou, Sue Jordan, Daniel Thayer, Clara L. Rodríguez‐Bernal, Francisco Sánchez‐Sáez, Régis Lassalle, Marie‐Agnès Bernard, Ema Alsina, Fariba Ahmadizar, Guillaume Favre, Alice Panchaud, Kitty W. M. Bloemenkamp, Kelly Plueschke, Corinne de Vries, Satu J. Siiskonen, Miriam C. J. M. Sturkenboom, on behalf of the CONSIGN Collaboration Group, Benjamin P. Geisler, Mark Walker, Steven Hawken, Sasha Bernatsky, Sherif Eltonsy, Emma Hoffman, Andrew B. Petrone, Jolene Mosley, Jenice Ko, Claudia Bartolini, Giuseppe Roberto, Giorgio Limoncella, Anna Girardi, Giulia Hyeraci, Antonio Gimeno‐Miguel, Jonás Carmona‐Pírez, Antonio Poncel‐Falcó, Aida Moreno‐Juste, Alexandra Prados‐Torres, Ian Farr, Saira Ahmed, Ieuan Scanlon, Gabriel Sanfélix‐Gimeno, Isabel Hurtado, Anibal Garcia‐Sempere, Salvador Peiro, Jérémy Jové, Dunia Sakr, Cécile Droz‐Perroteau, David Baum, Hilde M. Engjom, Mònica Sabaté Gallego, Elena Ballarín Alins, Cristina Aguilera Martin, Melissa Kampman, Celline Brasil   +72 more
wiley   +1 more source

Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions [PDF]

, 2014
Antimicrobials targeting cell wall biosynthesis are generally considered inactive against nonreplicating bacteria. Paradoxically, we found that under nonpermissive growth conditions, exposure of Mycobacterium bovis BCG bacilli to such antimicrobials ...
Andrew, Peter W, Burke, Bernard, Butcher, Philip D, Cohen-Gonsaud, Martin, Glenn, Sarah, Labesse, Gilles, Mukamolova, Galina V, Sarybaeva, Asel A, Tudo, Griselda, Turapov, Obolbek, Waddell, Simon J, Young, Danielle I, Young, Michael   +12 more
core   +2 more sources

In vitro antimycobacterial activities of pyrazinamide analogs [PDF]

Antimicrobial Agents and Chemotherapy, 1995
We synthesized various pyrazine derivatives and pyrazinamide analogs and assayed their antimycobacterial activities in vitro in order to find new drugs which are more active against Mycobacterium tuberculosis than pyrazinamide and also active against Mycobacterium avium and Mycobacterium intracellulare.
S, Yamamoto, I, Toida, N, Watanabe, T, Ura   +3 more
openaire   +2 more sources

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

ChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala, Janardan Sannapaneni, Phani Raja Kanuparthy, Venkata Ramana Singamaneni, Tejeswara Rao Allaka, Pilli Veera Venkata Nanda Kishore   +5 more
wiley   +1 more source

Antimycobacterial Activity and Brine Shrimp Toxicity of Wild Mushrooms Used by Communities in Southern Tanzania [PDF]

Research Journal of Pharmacognosy
Background and objectives: Several wild mushroom species occur in southern Tanzania and are used as food by the local tribes. Experience shows that some of them could contain phytochemical compounds with therapeutic potential for treating various ...
Michael Qwarse*, Mainen Julius Moshi, Matobola Joel Mihale, Alphonce Ignace Marealle, Ramadhani Selemani Omari Nondo, Joseph Sempombe, Veronica Mugoyela   +6 more
doaj   +1 more source

Antimycobacterial activity of selected medicinal plants extracts from Cameroon [PDF]

, 2014
New drugs are highly needed to control mycobacterial infections. This study aimed at screening ethnobotanically selected plants extracted using organic solvents for their antimycobacterial activity.
Boyom, Fabrice Fekam, Donfack, Valerie Flore Donkeng, Fokou, Patrick Valere Tsouh, Neves, Margarida Correia, Roque, Susana, Tchokouaha, Lauve Rachel Yamthe, Trigo, Gabriela, Tsabang, Nole, Zollo, Paul Henri Amvam   +8 more
core   +2 more sources