Results 71 to 80 of about 11,373 (215)

Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives [PDF]

, 2013
A total of seven novel benzimidazoles were synthesized by a 4-step reaction starting from 4-fluoro-3-nitrobenzoic acid under relatively mild reaction conditions.The synthesized compounds were screened for their antimycobacterial activity against M ...
Ang, Chee Wei, Ali, Mohamed Ashraf, Yeong, Keng Yoon, Tan, Soo Choon, Kumar, Raju Suresh, Osman, Hasnah, Beevi, Farzana, Ismail, Rusli   +7 more
core   +1 more source

Antimycobacterial and anti-inflammatory activities of metabolites from endophytic and soil fungi

Phytomedicine Plus, 2022
Background: Increased prevalence of high virulent strains of Mycobacterium tuberculosis and M. kansasii require the development of new antimycobacterial drugs safe and more effective.
Willian Jonis Andrioli, Thatiana Lopes Bia Ventura Simão, Daniella Passos Ferreira, Marlon Heggdorne Araújo, Sanderson Dias Calixto, Jairo K. Bastos, Lucy Seldin, Elena Lasunskaia, Michelle Frazão Muzitano   +8 more
doaj   +1 more source

Antimycobacterial Activities of Novel Levofloxacin Analogues [PDF]

Antimicrobial Agents and Chemotherapy, 2000
ABSTRACT In order to investigate structure-activity relationships between antimycobacterial activities and basic substituents at the C-10 position of levofloxacin (LVFX), we synthesized a series of pyridobenzoxazine derivatives by replacement of the N -methylpiperazinyl group of LVFX with various basic ...
K, Kawakami, K, Namba, M, Tanaka, N, Matsuhashi, K, Sato, M, Takemura   +5 more
openaire   +2 more sources

Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long‐Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Esmat Davoudi‐Monfared, Fatemeh Shahabi, Asieh Sadat Fattahi, Marzieh Rahimi, Mahsa Akbari Oryani, Azadeh Jabbari Nooghabi   +5 more
wiley   +1 more source

Antimycobacterial Mechanisms and Anti-Virulence Activities of Polyphenolic-Rich South African Medicinal Plants Against Mycobacterium smegmatis

Microorganisms
The rise of multidrug-resistant tuberculosis (TB) necessitates alternative therapeutic sources. This study investigated the polyphenolic content and the antioxidant, antimycobacterial, and anti-virulence activities of selected medicinal plants ...
Matsilane L. Mashilo, Mashilo M. Matotoka, Peter Masoko   +2 more
doaj   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Screening antimycobacterial activity of Baccharis dracunculifolia, Centella asiatica, Lantana camara and Pterodon emarginatus

Revista Brasileira de Plantas Medicinais, 2015
The permanent investigation of new antimycobacterial drugs is necessary for the eradication programs of tuberculosis and other mycobacterium-related diseases.
R.R.P. MACHADO, R.C. DUTRA, F. PITTELLA, N.R.B. RAPOSO, B. LESCHE, R.S. DUARTE, G.L.G. SOARES, M.A.C. KAPLAN   +7 more
doaj   +1 more source

Advances in Research on the Anti‐Tuberculosis Effects of Active Components in Chinese Herbal Medicine

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
This review summarizes how active constituents derived from Chinese herbal medicine exert anti‐tuberculosis (TB) effects via immunomodulation, direct inhibition of pathogens, and antioxidant activity. This synergistic, multi‐pathway mechanism highlights their potential as promising therapeutic candidates and adjunctive treatments against drug‐resistant
Qianqian Zhang, Siqi Lin, Juan Liu, Huani Wu, Xiaodan Lin, Jiawen He, Qiaoyu Yang, Jiang Pi, Fen Yang   +8 more
wiley   +1 more source

Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound

Scientia Pharmaceutica, 2017
Twelve N-substituted-glycinyl triazolyl oxazolidinone derivatives were screened for antimycobacterial activity against susceptible (Mycobacterium tuberculosis (Mtb) H37Rv) and resistant (isoniazid (INH)-resistant Mtb (SRI 1369), rifampin (RMP)-resistant ...
Naser F. Al-Tannak, Oludotun A. Phillips
doaj   +1 more source

Bis dihydropyrimidine: synthesis and antimycobacterial activity [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2010
A series of bis dihydropyrimidine compounds were synthesised by reacting dapsone with acetylacetoacetate to produce N1-4-[4-(2-oxopropylcarboxamido) phenylsulphonyl] phenyl-3-oxobutanamide, then treated with guanidine hydrochloride and an appropriate aldehyde with a catalytic amount of p-toluene sulphonic acid (PTSA) in the presence of methanol to ...
Mohamed Ashraf, Ali, Elumalai, Manogaran, Jeyabalan, Govindasamy, Velmurugan, Sellappan, Suresh, Pandian   +4 more
openaire   +2 more sources