Results 81 to 90 of about 11,373 (215)
Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley +1 more source
ABSTRACT Background Digital databases such as pharmacovigilance (PV) databases could provide unique opportunities to monitor trends in suspected antibiotic resistance, ineffectiveness, and misuse, extending beyond their traditional role of tracking adverse drug reactions (ADRs).
Hager Saleh +3 more
wiley +1 more source
Antibacterial, antifungal, and antimycobacterial activity of Ilex aquifolium leaves [PDF]
WOS: 000269481300007The objective of this study was to examine antibacterial, antifungal, and antimycobacterial properties of flex aquifolium L. (Aquifoliaceae) growing in Turkey.
Şener, Bilge +5 more
core +1 more source
The persistence of Mycobacterium tuberculosis within biofilm-like structures underscores the need for alternative drug discovery strategies aimed at resistance mechanisms.
Ramokone Mothupi +3 more
doaj +1 more source
Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages. [PDF]
Latent M. tuberculosis infection presents one of the major obstacles in the global eradication of tuberculosis (TB). Cholesterol plays a critical role in the persistence of M. tuberculosis within the macrophage during latent infection.
Areej Abuhammad +13 more
doaj +1 more source
We report the synthesis of 21 novel thiazolidinedione–pyrazolopyrimidinone derivatives (12a–u), prepared by coupling thiazolidinedione and pyrazolopyrimidinone pharmacophores through various alkyl linkers. The compounds were characterized spectroscopically and evaluated against the Mtb H37Rv strain, identifying compounds 5c and 5d as potent ...
Pule Seboletswe +8 more
wiley +1 more source
Synthesis and structure-antimycobacterial activity relationship study of dinitrobenzylsulfanyl heteroaromates [PDF]
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Inorganic and Organic Chemistry Candidate: Ing. Galina Karabanovich Supervisor: Prof. PharmDr. Alexandr Hrabálek, CSc. Consultant: PharmDr. Jaroslav Roh, Ph.D.
Karabanovich, Galina
core
Hybrid imidazole (benzimidazole)/pyridine (quinoline) derivatives and evaluation of their anticancer and antimycobacterial activity [PDF]
The design, synthesis, structure, and in vitro anticancer and antimycobacterial activity of new hybrid imidazole (benzimidazole)/pyridine (quinoline) derivatives are described.
Ionel I. Mangalagiu (2554105) +4 more
core +1 more source
Experimental Observations on the Antimycobacterial Activity of Rifampin
SummaryExperimental studies in vitro and in vivo indicated that rifampin is highly active against both isoniazid-susceptible and isoniazid-resistant strains of M. tuberculosis. Although less active in vivo than isoniazid, at least in the dosages employed, it was highly active in combination with streptomycin, isoniazid, or ethambutol, or in combination
G. L. Hobby +2 more
openaire +2 more sources
Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis
ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram +5 more
wiley +1 more source

