Results 61 to 70 of about 8,621 (178)

Cutaneous Mycobacterium haemophilum Infection in an Immunosuppressed Host: A Case Report of Diagnostic Considerations and Microbiologic Confirmation

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cutaneous Mycobacterium haemophilum infection may be missed due to its requirement for iron supplementation and low‐temperature incubation, making early consideration of NTM infection and use of molecular diagnostics essential, particularly in immunocompromised hosts where IRIS may mimic disease progression.
Angus Lane, Amanda Godbolt, Sarah Morton, Heather Wiseby, Vivek Menon, Chris Coulter, Sushil Pandey, Andrew Burke   +7 more
wiley   +1 more source

Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound

Scientia Pharmaceutica, 2017
Twelve N-substituted-glycinyl triazolyl oxazolidinone derivatives were screened for antimycobacterial activity against susceptible (Mycobacterium tuberculosis (Mtb) H37Rv) and resistant (isoniazid (INH)-resistant Mtb (SRI 1369), rifampin (RMP)-resistant ...
Naser F. Al-Tannak, Oludotun A. Phillips
doaj   +1 more source

Integrative In Vitro and In Silico Evaluation of the Chemical Profile and Bioactivities of Tetraclinis articulata Essential Oil

ChemistrySelect, Volume 11, Issue 27, 17 July 2026.
Chemistry and bioactivity of Tetraclinis articulata EO: in vitro and in silico investigation. Insights into chemistry and bioactivities of T. articulata EO. ABSTRACT This research focuses on characterizing the chemical composition and evaluate the biological potentials of the Tetraclinis articulata essential oil (TAEO) extracted from aerial parts of ...
Bochra Medjadji, Fatiha Benahmed, Fatima Kerroum, Imededdine Kadi, Khelifa Bouacem, Fairouz El Aichar, Mohamed Abdesselem Dems, Tarek H. Taha, Walid Elfalleh, Stefania Garzoli, Hamdi Bendif   +10 more
wiley   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

Immunology, Volume 178, Issue 3, Page 494-505, July 2026.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur, Hubert S. Ahor, Monika M. Vivekanandan, Difery Minadzi, Augustine Yeboah, Millicent Lamptey, Victoria A. Ofori, Albert D. Kegya, Rejoice Arthur, Linda A. Amoakoa, Ernest Adankwah, Dorcas O. Owusu, Mohammed K. Abass, Fredrick Gyamfi Apraku, Nana K. Ayisi‐Boateng, Seth Adane, Salisu Zakaria, Ertan Mayatepek, Julia Seyfarth, Richard O. Phillips, Marc Jacobsen   +20 more
wiley   +1 more source

Bis dihydropyrimidine: synthesis and antimycobacterial activity [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2010
A series of bis dihydropyrimidine compounds were synthesised by reacting dapsone with acetylacetoacetate to produce N1-4-[4-(2-oxopropylcarboxamido) phenylsulphonyl] phenyl-3-oxobutanamide, then treated with guanidine hydrochloride and an appropriate aldehyde with a catalytic amount of p-toluene sulphonic acid (PTSA) in the presence of methanol to ...
Mohamed Ashraf, Ali, Elumalai, Manogaran, Jeyabalan, Govindasamy, Velmurugan, Sellappan, Suresh, Pandian   +4 more
openaire   +2 more sources

Investigating the Antimycobacterial, Antibiofilm, and Antioxidant Activities of Plant Extracts Against Mycobacterium smegmatis

Microorganisms
The persistence of Mycobacterium tuberculosis within biofilm-like structures underscores the need for alternative drug discovery strategies aimed at resistance mechanisms.
Ramokone Mothupi, Mashilo Matotoka, Gabriel Mashabela, Peter Masoko   +3 more
doaj   +1 more source

Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley   +1 more source

What Is the Significance of an Accelerated BCG Reaction in Children Living in Low Tuberculosis Incidence Countries?

Journal of Paediatrics and Child Health, Volume 62, Issue 7, Page 1186-1191, July 2026.
ABSTRACT Aim In high tuberculosis (TB) incidence countries, accelerated Bacille Calmette–Guérin (BCG) reactions are considered markers of prior Mycobacterium tuberculosis exposure and may prompt investigation. Their significance in low‐incidence countries is unclear.
Widad Al Salmi, Niall Johnston, Emma Birrell, Adam W. Bartlett, Pamela Palasanthiran, Brendan J. McMullan, Phoebe C. M. Williams   +6 more
wiley   +1 more source

Experimental Observations on the Antimycobacterial Activity of Rifampin

Experimental Biology and Medicine, 1969
SummaryExperimental studies in vitro and in vivo indicated that rifampin is highly active against both isoniazid-susceptible and isoniazid-resistant strains of M. tuberculosis. Although less active in vivo than isoniazid, at least in the dosages employed, it was highly active in combination with streptomycin, isoniazid, or ethambutol, or in combination
G. L. Hobby, T. F. Lenert, J. Maier-Engallena   +2 more
openaire   +2 more sources

High-throughput screening system for antimycobacterial compounds using in vitro infected cells: construction and application to compounds in the Ōmura Natural Compound Library

Microbiology Spectrum
The global increase in multidrug-resistant tuberculosis strains poses a major threat; consequently, there is an urgent need to identify and develop novel drugs.
Takemasa Takii, Aoi Kimishima, Masato Iwatsuki, Yoshihiro Watanabe, Naoya Ohara, Yukihiro Asami   +5 more
doaj   +1 more source