Results 51 to 60 of about 11,373 (215)
Antimycobacterial activity of the red algae gelidium pristoides, plocamium corallorhiza and polysiphonia virgata [PDF]
, 2006 Summary in English.In 1993, the World Health Organisation declared tuberculosis a global health emergency. Currently, efforts are underway to improve the way the disease is managed and to find more effective treatments that would combat the problem of ...
Saravanakumar, Denise
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Synthesis of aza-analogs of compounds with high antimycobacterial activity [PDF]
, 2022 Charles University Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemistry Author: Tomáš Khajl Supervisor: Ing. Galina Karabanovich, Ph.D.
Khajl, Tomáš
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Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim In high tuberculosis (TB) incidence countries, accelerated Bacille Calmette–Guérin (BCG) reactions are considered markers of prior Mycobacterium tuberculosis exposure and may prompt investigation. Their significance in low‐incidence countries is unclear.
Widad Al Salmi +6 more
wiley +1 more source
Heterocyclic Compounds with Antimycobacterial Activity [PDF]
, 2009 The dissertation thesis belongs to the conception of the research of potential antimycobacterial compounds. The aim of this work is synthesis of sulphide pyridine derivatives and the relationship between structure and antimycobacterial activity.
Herzigová, Petra
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Substituted N-Phenylpyrazine-2-carboxamides: Synthesis and Antimycobacterial Evaluation
Molecules, 2009 The condensation of chlorides of substituted pyrazinecarboxylic acids with ringsubstituted anilines yielded twelve substituted pyrazinecarboxylic acid amides.
Michaela Svobodová +4 more
doaj +1 more source
Design, synthesis and structure-activity relationship study of wollamide B; a new potential anti TB agent. [PDF]
PLoS ONE, 2017 Wollamide B is a cationic antimycobacterial cyclohexapeptide that exhibits activity against Mycobacterium bovis (M. bovis) (IC50 of 3.1 μM). Aiming to define its structural activity relationship (SAR), optimizing potency and pharmacokinetic properties ...
Henok Asfaw +7 more
doaj +1 more source
In Vitro Antimycobacterial Activity of 5-Chloropyrazinamide [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT 5-Chloropyrazinamide and 5-chloropyrazinoic acid were evaluated for in vitro activity against Mycobacterium tuberculosis , Mycobacterium bovis , and several nontuberculous mycobacteria by a broth dilution method.
M H, Cynamon, R J, Speirs, J T, Welch
openaire +2 more sources
Immunology, Volume 178, Issue 3, Page 494-505, July 2026.TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur +20 more
wiley +1 more source
Natural Product Communications, 2014 An extract of Seimatosporium sp., an endophyte from the Canadian medicinal plant Hypericum perforatum , exhibited significant antifungal and antimycobacterial activity against Candida albicans and Mycobacterium tuberculosis H37Ra.
Trevor N. Clark +5 more
doaj +1 more source
Enhancement of the antimycobacterial activity of macrophages by ajoene [PDF]
Innate Immunity, 2017 Ajoene, a garlic-derived sulfur-containing compound, has broad-spectrum antimicrobial activity. To assess the potential of ajoene for treating tuberculosis (TB), we determined whether it induces the stress response of the endoplasmic reticulum (ER), which plays an important role in TB.
Choi, Ji-Ae +6 more
openaire +2 more sources