Results 41 to 50 of about 8,621 (178)
Enhancement of the antimycobacterial activity of macrophages by ajoene [PDF]
Innate Immunity, 2017 Ajoene, a garlic-derived sulfur-containing compound, has broad-spectrum antimicrobial activity. To assess the potential of ajoene for treating tuberculosis (TB), we determined whether it induces the stress response of the endoplasmic reticulum (ER), which plays an important role in TB.
Choi, Ji-Ae +6 more
openaire +2 more sources
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham +11 more
wiley +2 more sources
Archiv der Pharmazie, Volume 359, Issue 8, August 2026.This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan +2 more
wiley +1 more source
Substituted N-Phenylpyrazine-2-carboxamides: Synthesis and Antimycobacterial Evaluation
Molecules, 2009 The condensation of chlorides of substituted pyrazinecarboxylic acids with ringsubstituted anilines yielded twelve substituted pyrazinecarboxylic acid amides.
Michaela Svobodová +4 more
doaj +1 more source
Design, synthesis and structure-activity relationship study of wollamide B; a new potential anti TB agent. [PDF]
PLoS ONE, 2017 Wollamide B is a cationic antimycobacterial cyclohexapeptide that exhibits activity against Mycobacterium bovis (M. bovis) (IC50 of 3.1 μM). Aiming to define its structural activity relationship (SAR), optimizing potency and pharmacokinetic properties ...
Henok Asfaw +7 more
doaj +1 more source
International Journal of Mycobacteriology, 2021 Background: Buruli ulcer (BU) is a neglected tropical disease caused by the Mycobacterium ulcerans. BU is an endemic disease in many communities in sub-Saharan Africa where population have long history of using medicinal plants for treatment.
Isaac Kingsley Amponsah +7 more
doaj +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2937-2948, August 2026.Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber +7 more
wiley +1 more source
Natural Product CommunicationsObjective Actinomycetes have been known to be the great natural sources to explore antibiotics for the treatment of tuberculosis (TB). The isolation of actinomycetes from the samples in Vietnam followed by the screening of their antimycobacterial ...
Ni Thi Ngoc Huynh +13 more
doaj +1 more source
Natural Product Communications, 2014 An extract of Seimatosporium sp., an endophyte from the Canadian medicinal plant Hypericum perforatum , exhibited significant antifungal and antimycobacterial activity against Candida albicans and Mycobacterium tuberculosis H37Ra.
Trevor N. Clark +5 more
doaj +1 more source
The Antimycobacterial Activity, Toxicity and Chemical Composition of South African Propolis
Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.This study presents one of the largest geographically diverse propolis collections reported globally, comprising 109 samples sourced from eight provinces across South Africa. The novelty of this work lies in the fact that it presents the first investigation of South African propolis against M. tuberculosis.
Nyiko F. Mzimba +6 more
wiley +1 more source