Results 21 to 30 of about 11,373 (215)

Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine [PDF]

, 2015
The interaction of quinolone and indoloquinazoline alkaloids concerning their antimycobacterial activity was studied. Methods and Results: The antimycobacterial and modulating activity of evodiamine (1), rutaecarpine (2) and evocarpine (3) was tested on ...
Hochfellner, C., Mchugh, T. D., Bucar, F., Kunert, O., Evangelopoulos, D., Zloh, Mire, Guzman, J. D., Bhakta, S., Wube, A.   +8 more
core   +3 more sources

Acetophenones with selective antimycobacterial activity [PDF]

Letters in Applied Microbiology, 2005
Mycobacteria are a serious cause of infections in humans, with limited treatment options, as no new antibiotics have been developed against mycobacteria since the 1960s. In this study, the antimycobacterial activity of a small library of acetophenone (AP) compounds was analysed.Twenty-three AP derivatives were examined for activity against mycobacteria
L, Rajabi, C, Courreges, J, Montoya, R J, Aguilera, T P, Primm   +4 more
openaire   +2 more sources

In-vitro evaluation of the antibacterial activity of the essential oils of Micromeria barbata, Eucalyptus globulus and Juniperus excelsa against strains of Mycobacterium tuberculosis (including MDR), Mycobacterium kansasii and Mycobacterium gordonae

Journal of Infection and Public Health, 2019
Background: Mycobacterium spp. are responsible for several diseases, particularly in immunocompromised populations. The spreading of the resistance to antimycobacterial drugs is a significant problem to the public health and requires to find out a new ...
Khaled El Omari, Monzer Hamze, Saer Alwan, Marwan Osman, Charafeddine Jama, Nour-Eddine Chihib   +5 more
doaj   +1 more source

Antimycobacterial activity of synthetic pamamycins [PDF]

Journal of Antimicrobial Chemotherapy, 2004
Early studies have indicated that pamamycins, a group of macrodiolides first isolated from Streptomyces alboniger, have potent antimicrobial activity against Gram-positive bacteria, fungi and mycobacteria but not against Gram-negative bacteria. The recent availability of highly purified and reasonable quantities of several pamamycins through their ...
Lefèvre, Philippe, Peirs, Priska, Braibant, Martine, Fauville, Maryse, Vanhoof, Raymond, Huygen, Kris, Wang, Xiao-Ming, Pogell, B, Wang, Y, Fischer, P, Metzger, Patricia, Content, Jean   +11 more
openaire   +3 more sources

The Efficacy of the Crude Root Bark Extracts of Erythrina Abyssinica on Rifampicin Resistant Mycobacterium Tuberculosis. [PDF]

, 2011
Tuberculosis (TB) is one of the leading causes of morbidity and mortality with a global mortality rate at two million deaths per year while one third of the world's population is infected with the TB bacillus.
Orodho, J.A., Bunalema, L, Bunalema, L., Kirimuhuzya, C., Orodho, J A, Tabuti, J.R., Kirimuhuzya, C, Magadula, J J, Otieno, N., Okemo, P, Otieno, N, Tabuti, JRS, Orodho, JA, Magadula, J.J., Waako, P., Tabuti, J R S, Waako, P, Magadula, JJ   +17 more
core   +1 more source

Antimycobacterial Activity of Lichens [PDF]

Pharmaceutical Biology, 2007
Ethanol extracts of nine lichen species, namely Everniastrum cirrhatum (Fr.) Hale ex Sipman (Parmeliaceae), Flavoparmelia caperata (L) Hale (Parmeliaceae), Heterodermia leucomela (L) Poelt (Physciaceae), Lecanora flavidorufa Hue (Lecanoraceae), Leptogium pedicellatum P.M.
Vivek Kumar Gupta, Mahendra P. Darokar, Dharmendra Saikia, Anirban Pal, Atiya Fatima, Suman P.S. Khanuja   +5 more
openaire   +1 more source

In vitro antimycobacterial and cytotoxic data on medicinal plants used to treat tuberculosis

Data in Brief, 2016
This article contains data on in vitro antimycobacterial activity and cytotoxicity of hydroethanolic crude extracts from five selected medicinal plant species traditionally used to treat tuberculosis in Ghanaian ethnomedicine, see “Medicinal plants used ...
Joseph M. Nguta, Regina Appiah-Opong, Alexander K. Nyarko, Dorothy Yeboah-Manu, Phyllis G.A. Addo, Isaac D. Otchere, Abena Kissi-Twum   +6 more
doaj   +1 more source

Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp²)-H-Hydroxylation

Pharmaceuticals, 2022
The continuous, worldwide spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) endanger the World Health Organization’s (WHO) goal to end the global TB pandemic by the year 2035.
Alexander Berger, Talea Knak, Anna-Lene Kiffe-Delf, Korana Mudrovcic, Vinayak Singh, Mathew Njoroge, Bjoern B. Burckhardt, Mohanraj Gopalswamy, Beate Lungerich, Lutz Ackermann, Holger Gohlke, Kelly Chibale, Rainer Kalscheuer, Thomas Kurz   +13 more
doaj   +1 more source

Antimycobacterial activity of lichen substances

Phytomedicine, 2010
We describe here the extraction and identification of several classes of phenolic compounds from the lichens Parmotrema dilatatum (Vain.) Hale, Parmotrema tinctorum (Nyl.) Hale, Pseudoparmelia sphaerospora (Nyl.) Hale and Usnea subcavata (Motyka) and determined their anti-tubercular activity.
Honda, N. K., Pavan, Fernando Rogério, Coelho, R. G., de Andrade Leite, S. R., Micheletti, A. C., Lopes, T. I. B., Misutsu, M. Y., Beatriz, A., Brum, R. L., Leite, Clarice Queico Fujimura   +9 more
openaire   +3 more sources

Acetone leaf extracts of some South African trees with high activity against Escherichia coli also have good antimycobacterial activity and selectivity index

BMC Complementary and Alternative Medicine, 2017
Background Tuberculosis is a world-wide problem affecting humans and animals. There is increasing development of resistance of the pathogens to current antimycobacterial agents. Many authors have investigated activities of extracts and isolated compounds
Ishaku L. Elisha, Francien S. Botha, Balungile Madikizela, Lyndy J. McGaw, Jacobus N. Eloff   +4 more
doaj   +1 more source