Results 11 to 20 of about 8,621 (178)

Antimycobacterial and cytotoxicity activity of microcystins [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu1] microcystin-LR. Methods The antimicrobial activity of M. aeruginosa extract
Daniela Fernandes Ramos, Alexandre Matthiensen, Wilson Colvara, Ana Paula Souza de Votto, Gilma Santos Trindade, Pedro Eduardo Almeida da Silva, João Sarkis Yunes   +6 more
doaj   +4 more sources

Antimycobacterial activities of riminophenazines [PDF]

Journal of Antimicrobial Chemotherapy, 1999
Riminophenazines were specifically developed as drugs active against Mycobacterium tuberculosis but extensive research over several decades has shown that these compounds are also active against many other mycobacterial infections, particularly those caused by Mycobacterium leprae and the Mycobacterium avium complex (MAC).
V M, Reddy, J F, O'Sullivan, P R, Gangadharam   +2 more
openaire   +2 more sources

Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis

Microbiology Spectrum, 2023
Shorter and more effective treatment regimens as well as new drugs are urgent priorities for reducing the immense global burden of tuberculosis (TB). As treatment of TB currently requires multiple antibiotics with diverse mechanisms of action, any new ...
Rachel F. Rollo, Giorgia Mori, Timothy A. Hill, Doris Hillemann, Stefan Niemann, Susanne Homolka, David P. Fairlie, Antje Blumenthal   +7 more
doaj   +1 more source

Acetophenones with selective antimycobacterial activity [PDF]

Letters in Applied Microbiology, 2005
Mycobacteria are a serious cause of infections in humans, with limited treatment options, as no new antibiotics have been developed against mycobacteria since the 1960s. In this study, the antimycobacterial activity of a small library of acetophenone (AP) compounds was analysed.Twenty-three AP derivatives were examined for activity against mycobacteria
L, Rajabi, C, Courreges, J, Montoya, R J, Aguilera, T P, Primm   +4 more
openaire   +2 more sources

Antimycobacterial activity of synthetic pamamycins [PDF]

Journal of Antimicrobial Chemotherapy, 2004
Early studies have indicated that pamamycins, a group of macrodiolides first isolated from Streptomyces alboniger, have potent antimicrobial activity against Gram-positive bacteria, fungi and mycobacteria but not against Gram-negative bacteria. The recent availability of highly purified and reasonable quantities of several pamamycins through their ...
Lefèvre, Philippe, Peirs, Priska, Braibant, Martine, Fauville, Maryse, Vanhoof, Raymond, Huygen, Kris, Wang, Xiao-Ming, Pogell, B, Wang, Y, Fischer, P, Metzger, Patricia, Content, Jean   +11 more
openaire   +3 more sources

In-vitro evaluation of the antibacterial activity of the essential oils of Micromeria barbata, Eucalyptus globulus and Juniperus excelsa against strains of Mycobacterium tuberculosis (including MDR), Mycobacterium kansasii and Mycobacterium gordonae

Journal of Infection and Public Health, 2019
Background: Mycobacterium spp. are responsible for several diseases, particularly in immunocompromised populations. The spreading of the resistance to antimycobacterial drugs is a significant problem to the public health and requires to find out a new ...
Khaled El Omari, Monzer Hamze, Saer Alwan, Marwan Osman, Charafeddine Jama, Nour-Eddine Chihib   +5 more
doaj   +1 more source

Antimycobacterial activity of the plectasin derivative NZ2114. [PDF]

Front Microbiol
IntroductionMycobacteria have a unique hydrophobic membrane with several lipid-enriched layers that are low in permeability, setting them apart from other bacteria. This complex structure, consisting of three distinct layers is crucial for cell growth, virulence, and providing a barrier to antibiotics. Previously, we identified a plectasin variant, NZX,
Davids C, Rao-Fransson K, Krishnan N, Tenland E, Mörgelin M, Robertson B, Godaly G.   +6 more
europepmc   +4 more sources

Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins [PDF]

ACS Medicinal Chemistry Letters, 2012
Dihydropyridomycins 2 and 3, which lack the characteristic enol ester moiety of the potent antimycobacterial natural product pyridomycin (1), have been prepared from l-Thr, R- and S-hydroxy isovaleric acid, and 3-pyridinecarboxaldehyde. The 2R isomer 2 shows only 4-fold lower anti-Mtb activity than 1, indicating that the enol ester moiety in the ...
Oliver P. Horlacher, Ruben C. Hartkoorn, Stewart T. Cole, Karl-Heinz Altmann   +3 more
openaire   +3 more sources

Antimycobacterial Activity of Lichens [PDF]

Pharmaceutical Biology, 2007
Ethanol extracts of nine lichen species, namely Everniastrum cirrhatum (Fr.) Hale ex Sipman (Parmeliaceae), Flavoparmelia caperata (L) Hale (Parmeliaceae), Heterodermia leucomela (L) Poelt (Physciaceae), Lecanora flavidorufa Hue (Lecanoraceae), Leptogium pedicellatum P.M.
Vivek Kumar Gupta, Mahendra P. Darokar, Dharmendra Saikia, Anirban Pal, Atiya Fatima, Suman P.S. Khanuja   +5 more
openaire   +1 more source

In vitro antimycobacterial and cytotoxic data on medicinal plants used to treat tuberculosis

Data in Brief, 2016
This article contains data on in vitro antimycobacterial activity and cytotoxicity of hydroethanolic crude extracts from five selected medicinal plant species traditionally used to treat tuberculosis in Ghanaian ethnomedicine, see “Medicinal plants used ...
Joseph M. Nguta, Regina Appiah-Opong, Alexander K. Nyarko, Dorothy Yeboah-Manu, Phyllis G.A. Addo, Isaac D. Otchere, Abena Kissi-Twum   +6 more
doaj   +1 more source