Results 31 to 40 of about 11,373 (215)

Antimycobacterial activity of some medicinal plants in Niger state, Nigeria [PDF]

, 2010
Ten Nigerian medicinal plants Abrus precatorius, Annona senegalensis, Anogeissus leiocarpus, Crateva adansonii, Detarium microcarpum, Faba spp, Neocarya macrophylla, Ocimum gratissimum, Securidacalongpenduculata and Terminalia avicennioides used by ...
A Mann, J Okogun, K Ibrahim, Oyewale, A, J Amupitan, Ibrahim, K, A Oyewale, Amupitan, J, Mann, A, Okogun, J   +9 more
core   +2 more sources

Design, synthesis and antimycobacterial evaluation of some new azaheterocycles with the 4,7-phenanthroline skeleton. Part VI [PDF]

Journal of the Serbian Chemical Society, 2016
A feasible study concerning the synthesis, structure and in vitro antimycobacterial evaluation of new 4,7-phenanthroline derivatives is reported. The preparation is straight and efficient, involving an N-alkylation reaction of 4,7-phenanthroline.
Al Matarneh Cristina M., Ciobanu Catalina I., Mangalagiu Ionel I., Danac Ramona   +3 more
doaj   +1 more source

Isolation of the Plant Hormone (+)-Abscisic acid as an Antimycobacterial Constituent of the Medicinal Plant Endophyte sp

Natural Product Communications, 2013
An extract of the endophytic fungus Nigropsora sp. (isolate TC2-054) from the Canadian medicinal plant Fragaria virginiana exhibited significant antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
Trevor N. Clark, Katelyn Ellsworth, Haoxin Li, John A. Johnson, Christopher A. Gray   +4 more
doaj   +1 more source

Antimycobacterial activity of bacteriocins and their complexes with liposomes [PDF]

Journal of Antimicrobial Chemotherapy, 2007
Bacteriocins (Bcn) are natural peptides that are secreted by several taxonomically distant bacteria and exert bactericidal activity against other bacterial species. Their capacity to inhibit growth of virulent Mycobacterium tuberculosis H37Rv was evaluated in this study.Five different Bcn were isolated and purified from bacterial culture supernatants ...
Vasily, Sosunov, Vladimir, Mischenko, Boris, Eruslanov, Edward, Svetoch, Yulia, Shakina, Norman, Stern, Konstantin, Majorov, Galina, Sorokoumova, Alla, Selishcheva, Alexander, Apt   +9 more
openaire   +2 more sources

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +2 more sources

In Vitro Antimycobacterial Activities of Capuramycin Analogues [PDF]

Antimicrobial Agents and Chemotherapy, 2008
ABSTRACT Translocase I inhibitor compounds derived from capuramycin demonstrated rapid bactericidal activity against several different mycobacterial species. SQ641 was the most active of the compounds, with a MIC of 0.12 to 8 μg/ml, a postantibiotic effect of 55 h, and interesting synergistic effects with other antitubercular drugs.
Venkata M, Reddy, Leo, Einck, Carol A, Nacy   +2 more
openaire   +2 more sources

Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins [PDF]

, 2016
Dihydropyridomycins 2 and 3, which lack the characteristic enol ester moiety of the potent antimycobacterial natural product pyridomycin (1), have been prepared from l-Thr, R- and S-hydroxy isovaleric acid, and 3-pyridinecarboxaldehyde.
Karl-Heinz Altmann (396152), Oliver P. Horlacher (1993207), Ruben C. Hartkoorn (1327599), Stewart T. Cole (142597)   +3 more
core   +1 more source

Isolation of Phomopsolide A and 6(E)-Phomopsolide A as Antimycobacterial Products from an Unidentified Endophyte of the Canadian Medicinal Plant

Natural Product Communications, 2015
An extract of an unidentified endophyte from the Canadian medicinal plant Heracleum maximum exhibited a unique metabolomic profile and significant antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
Trevor N. Clark, Katelyn T. Ellsworth, Stephanie Jean, Duncan Webster, Gilles A. Robichaud, John A. Johnson, Christopher A. Graya   +6 more
doaj   +1 more source

Efficacy and Mechanisms of Flavonoids against the Emerging Opportunistic Nontuberculous Mycobacteria

Antibiotics, 2020
Nontuberculous mycobacteria (NTM) are the causative agent of severe chronic pulmonary diseases and is accountable for post-traumatic wound infections, lymphadenitis, endometritis, cutaneous, eye infections and disseminated diseases.
Suresh Mickymaray, Faiz Abdulaziz Alfaiz, Anand Paramasivam   +2 more
doaj   +1 more source

Antimycobacterial activities of novel fluoroquinolones

Biomedicine & Pharmacotherapy, 2009
Fifty-one novel 1-(cyclopropyl/2,4-difluorophenyl/t-butyl)-1,4-dihydro-6-fluoro-7-(sub secondary amino)-4-oxoquinoline-3-carboxylic acids were synthesized and evaluated for their antimycobacterial in vitro and in vivo against Mycobacterium tuberculosis H37Rv (MTB), multi-drug resistant Mycobacterium tuberculosis (MDR-TB) and Mycobacterium smegmatis (MC(
Senthilkumar, Palaniappan, Dinakaran, Murugesan, Yogeeswari, Perumal, china, Arnab, Nagaraja, Valakunja, Sriram, Dharmarajan   +5 more
openaire   +2 more sources