Results 31 to 40 of about 19,828 (226)

Acetone leaf extracts of some South African trees with high activity against Escherichia coli also have good antimycobacterial activity and selectivity index

BMC Complementary and Alternative Medicine, 2017
Background Tuberculosis is a world-wide problem affecting humans and animals. There is increasing development of resistance of the pathogens to current antimycobacterial agents. Many authors have investigated activities of extracts and isolated compounds
Ishaku L. Elisha, Francien S. Botha, Balungile Madikizela, Lyndy J. McGaw, Jacobus N. Eloff   +4 more
doaj   +1 more source

Design, synthesis and antimycobacterial evaluation of some new azaheterocycles with the 4,7-phenanthroline skeleton. Part VI [PDF]

Journal of the Serbian Chemical Society, 2016
A feasible study concerning the synthesis, structure and in vitro antimycobacterial evaluation of new 4,7-phenanthroline derivatives is reported. The preparation is straight and efficient, involving an N-alkylation reaction of 4,7-phenanthroline.
Al Matarneh Cristina M., Ciobanu Catalina I., Mangalagiu Ionel I., Danac Ramona   +3 more
doaj   +1 more source

Antimycobacterial activity of selected medicinal plants extracts from Cameroon [PDF]

, 2014
New drugs are highly needed to control mycobacterial infections. This study aimed at screening ethnobotanically selected plants extracted using organic solvents for their antimycobacterial activity.
Boyom, Fabrice Fekam, Donfack, Valerie Flore Donkeng, Fokou, Patrick Valere Tsouh, Neves, Margarida Correia, Roque, Susana, Tchokouaha, Lauve Rachel Yamthe, Trigo, Gabriela, Tsabang, Nole, Zollo, Paul Henri Amvam   +8 more
core   +2 more sources

Antimycobacterial activities of novel fluoroquinolones

Biomedicine & Pharmacotherapy, 2009
Fifty-one novel 1-(cyclopropyl/2,4-difluorophenyl/t-butyl)-1,4-dihydro-6-fluoro-7-(sub secondary amino)-4-oxoquinoline-3-carboxylic acids were synthesized and evaluated for their antimycobacterial in vitro and in vivo against Mycobacterium tuberculosis H37Rv (MTB), multi-drug resistant Mycobacterium tuberculosis (MDR-TB) and Mycobacterium smegmatis (MC(
Senthilkumar, Palaniappan, Dinakaran, Murugesan, Yogeeswari, Perumal, china, Arnab, Nagaraja, Valakunja, Sriram, Dharmarajan   +5 more
openaire   +2 more sources

Antimycobacterial Activity ofTaxus baccata [PDF]

Pharmaceutical Biology, 2003
Crude extracts prepared from various parts of Taxus baccata L. have been evaluated for their antimycobacterial activity. A CHCl3 fraction of the heartwood and ethanol extract of the leaves exhibited a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H37Ra strain of 200 µg/ml.
Palittapongarnpim, P, Sener, B, Erdemoglu, N   +2 more
openaire   +2 more sources

Bis dihydropyrimidine: synthesis and antimycobacterial activity [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2010
A series of bis dihydropyrimidine compounds were synthesised by reacting dapsone with acetylacetoacetate to produce N1-4-[4-(2-oxopropylcarboxamido) phenylsulphonyl] phenyl-3-oxobutanamide, then treated with guanidine hydrochloride and an appropriate aldehyde with a catalytic amount of p-toluene sulphonic acid (PTSA) in the presence of methanol to ...
Mohamed Ashraf, Ali, Elumalai, Manogaran, Jeyabalan, Govindasamy, Velmurugan, Sellappan, Suresh, Pandian   +4 more
openaire   +2 more sources

Isolation of the Plant Hormone (+)-Abscisic acid as an Antimycobacterial Constituent of the Medicinal Plant Endophyte sp

Natural Product Communications, 2013
An extract of the endophytic fungus Nigropsora sp. (isolate TC2-054) from the Canadian medicinal plant Fragaria virginiana exhibited significant antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
Trevor N. Clark, Katelyn Ellsworth, Haoxin Li, John A. Johnson, Christopher A. Gray   +4 more
doaj   +1 more source

MmpL3 is the flippase for mycolic acids in mycobacteria [PDF]

, 2017
The defining feature of the mycobacterial outer membrane (OM) is the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable to external insults, including many antibiotics.
Chng, Shu-Sin, Meshcheryakov, Vladimir A., Poce, Giovanna, Xu, Zhujun   +3 more
core   +1 more source

Efficacy and Mechanisms of Flavonoids against the Emerging Opportunistic Nontuberculous Mycobacteria

Antibiotics, 2020
Nontuberculous mycobacteria (NTM) are the causative agent of severe chronic pulmonary diseases and is accountable for post-traumatic wound infections, lymphadenitis, endometritis, cutaneous, eye infections and disseminated diseases.
Suresh Mickymaray, Faiz Abdulaziz Alfaiz, Anand Paramasivam   +2 more
doaj   +1 more source

Protozoan-induced regulation of cyclic lipopeptide biosynthesis Is an effective predation defense mechanism for Pseudomonas fluorescens [PDF]

, 2009
Environmental bacteria are exposed to a myriad of biotic interactions that influence their function and survival. The grazing activity of protozoan predators significantly impacts the dynamics, diversification, and evolution of bacterial communities in ...
Bruijn, I., de, Cohen, M.F., Mazzola, M., Raaijmakers, J.M.   +3 more
core   +3 more sources