Results 71 to 80 of about 523,877 (311)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

The mutualistic fungus Piriformospora indica protects barley roots from a loss of antioxidant capacity caused by the necrotrophic pathogen Fusarium culmorum [PDF]

open access: yes, 2013
Fusarium culmorum causes root rot in barley (Hordeum vulgare), resulting in severely reduced plant growth and yield. Pretreatment of roots with chlamydospores of the mutualistic root-colonizing basidiomycete Piriformospora indica (Agaricomycotina ...
Balázs Barna   +7 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

ETHNO-GENETIC MARKERS OF ANTIOXIDANT SYSTEM (LITERATURE REVIEW)

open access: yesActa Biomedica Scientifica, 2013
Oxidative stress plays an important role in the pathogenesis a most of diseases. Important components of protecting cells from oxidative stress are antioxidant enzymes, whose activity is genetically determined, due to the presence in the structure of the
L. I. Kolesnikova   +2 more
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Effect of Seed Priming with Sodium-Ascorbate on Germination and some of Physiological Characteristics of Sesame (Seamum indicum) under Different Temperatures [PDF]

open access: yesIkufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2016
To study the effects of ascorbate and temperature on antioxidant enzymes and germination indexes, a factorial experimental based on completely randomized block design with three replications was conducted at the Agricultural Research Laboratory of ...
P. Tizfahm   +3 more
doaj  

The Role of Antioxidant to Prevent Free Radicals in The Body

open access: yesSains Medika, 2017
Antioxidants are compounds that can counteract or reduce the negative impact oxidants in the body. Antioxidants work by donating an electron to compounds that are oxidant so that the oxidant compound activity can be inhibited. Antioxidants are classified
Siti Thomas Zulaikhah
doaj   +1 more source

High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]

open access: yes, 2018
Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita   +8 more
core   +2 more sources

Relationship of antioxidant enzyme activities with myelomeningocele [PDF]

open access: yesTurkish Neurosurgery, 2011
To investigate the role of erythrocyte free radical scavenging enzyme activities (FRSE), carbonic anhydrase (CA) activity and malondialdehyde (MDA) in infants with myelomeningocele (MM).We compared antioxidant enzyme activities and MDA level in 40 individuals (10 infants with MM, 10 healthy infants; and mothers of these two groups) with age-matched ...
ESEOGLU, Metehan   +6 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy