Results 51 to 60 of about 495,387 (365)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comprehensive Evaluation of Probiotic Effects on Laying Hen Physiology: From Performance to Bone and Gut Morphology

Animals
This study investigated the effects of probiotic supplementation on performance, egg quality, antioxidant capacity, gut morphology, fecal microbiota, and bone morphology in Lohmann Brown laying hens aged 44 weeks over a 16-week period.
E. Ebru Onbaşılar, Sakine Yalçın, Caner Bakıcı, Barış Batur, Yeliz Kaya Kartal, Ozan Ahlat, İhsan Berat Kılıçlı, Suzan Yalçın   +7 more
doaj   +1 more source

Comparison of photosynthesis and antioxidant performance of several Citrus and Fortunella species under natural chilling stress : S08P24 [PDF]

, 2012
Citrus plants originate from southeastern Asia, in a large area with various climates characterized by a broad range of temperatures. Temperature is assumed to be a key factor in Citrus species adaptation and diversification.
Berti, Liliane, Giannettini, Jean, Herbette, Stéphane, Luro, François, Ollitrault, Patrick, Pailly, Olivier, Santini, Jérémie   +6 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Growth performance and antioxidant status of growing rabbits fed on diets supplemented with Eucommia ulmoides leaves

World Rabbit Science, 2018
The present study evaluated the effect of dietary Eucommia ulmoides leaves (EUL) on growth performance and antioxidant status of growing rabbits under heat stress condition.
Song Li, Miaoqing Zhao, Tingting Jiang, Wenwen Lv, Shujuan Gao, Yufa Zhou, Zengmin Miao   +6 more
doaj   +1 more source

Experimental inhibition of a key cellular antioxidant affects vocal communication [PDF]

, 2017
1. There is substantial interest of evolutionary ecologists in the proximate mechanisms that modulate vocal communication. In recent times, there has been growing interest in the role of oxidative stress as a mediator of avian song expression. 2.
Feare C.J., Griffith O.W., Griffith O.W., Halliwell B.H., Koren L., Messina S., R Core Team, Spencer K.A.   +7 more
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Effects of Dietary Rumen‐Protected Choline on Stress Alleviation, Antioxidant Modulation, and Haematological, Immunological, and Offspring Performance in Transitioning Goats

Veterinary Medicine and Science
The transition period is a crucial time for dairy animals, marked by significant physiological changes. This study investigated the effects of supplementing rumen‐protected choline (RPC) on oxidative stress, immune function, liver health and performance ...
Mohammad Asadi, Mostafa Bokharaeian, Homa Mohammadi Fard   +2 more
doaj   +1 more source

Oxidant/Antioxidant Status Is Impaired in Sepsis and Is Related to Anti-Apoptotic, Inflammatory, and Innate Immunity Alterations

Antioxidants, 2022
Oxidative stress is considered pivotal in the pathophysiology of sepsis. Oxidants modulate heat shock proteins (Hsp), interleukins (IL), and cell death pathways, including apoptosis.
Marianna Miliaraki, Panagiotis Briassoulis, Stavroula Ilia, Kalliopi Michalakakou, Theodoros Karakonstantakis, Aikaterini Polonifi, Kalliopi Bastaki, Efrossini Briassouli, Konstantinos Vardas, Aikaterini Pistiki, Maria Theodorakopoulou, Theonymfi Tavladaki, Anna-Maria Spanaki, Eumorfia Kondili, Helen Dimitriou, Maria Venihaki, Sotirios Tsiodras, Dimitrios Georgopoulos, Marina Mantzourani, Serafeim Nanas, Apostolos Armaganidis, George L. Daikos, Ioannis Papassotiriou, George Briassoulis   +23 more
doaj   +1 more source

Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis [PDF]

, 2010
Objective: The aim of this study was to determine the possible association of oxidant/antioxidant status and recurrent aphthous stomatitis (RAS). Study design: The study consis ted of thirty-one patients with RAS and thirty-two healthy controls from ...
Amanlou, Masoud, Mansourian, Arash, Momen Beitollahi, Jalil, Momen Heravi, Fatemeh, Obradov, Stoyana, SahebJamee, Mahnaz   +5 more
core   +1 more source