Results 61 to 70 of about 414,015 (313)
Animals, 2022 Cold climates may be a risk to the health and welfare of lambs during winter because cold environments alter the physiological processes of lambs, and we used cold environments with three different temperature gradients—an indoor heating control group ...
Lulu Shi +7 more
doaj +1 more source
Role of antioxidant supplementation and exercise regimen in handling oxidative stress from natural PM2.5 exposure due to boreal forest fire [PDF]
, 2019 Thesis (M.S.) University of Alaska Fairbanks, 2019Particulate matter 2.5 (PM2.5) exposure induces oxidative stress that causes many negative health outcomes such as cancer, cardiovascular disease and neurodegenerative disease. Research shows that dietary
Witkop, Jacob J.
core
Quantitative analysis of NRF2 pathway reveals key elements of the regulatory circuits underlying antioxidant response and proliferation of ovarian cancer cells [PDF]
, 2014 Cells are constantly exposed to Reactive Oxygen Species (ROS) produced both endogenously to meet physiological requirements and from exogenous sources.
Bown, James +5 more
core +4 more sources
Glaucoma and Antioxidant Status
, 2014 Glaucoma, one of the leading causes of irreversible blindness in the world, is defined as a slowly progressive optic neuropathy characterized by retinal nerve fiber and visual field loss. Although increased intraocular pressure is the major risk factor for glaucoma, other risk factors include advanced age, genetic predisposition, family history, gender,
Tosun, Mehmet +2 more
openaire +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Role of Osteopontin in Hypothyroid Anemic Woman and Their Association with Oxidative Stress
International Journal of Integrated Health SciencesBackground: Hypothyroidism is frequently associated with anemia and oxidative stress, necessitating exploration of biomarkers like Osteopontin to better understand disease mechanisms.
Sumesh Prasad Sah +5 more
doaj +1 more source
Italian Journal of Animal Science, 2021 The aim of this study was to determine the effect of vitamin E (α-Toc) and Otostgia persica leaf extract (OPLE) on the performance, immune response, and oxidative status in broiler chicken fed oxidised oil.
Saeid Jafari +2 more
doaj +1 more source
Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling [PDF]
, 2014 This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing.
Alessio +15 more
core +2 more sources
Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]
, 2020 Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A. +6 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source