Results 61 to 70 of about 1,389,776 (412)
Oxidants, antioxidants, and the degenerative diseases of aging.
Proceedings of the National Academy of Sciences of the United States of America, 1993 Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage (the same as that produced by radiation) is a major contributor to aging and
B. Ames, M. Shigenaga, T. Hagen
semanticscholar +1 more source
Antioxidants, 2023 Cancer is considered one of the main causes of human death worldwide, being characterized by an alteration of the oxidative metabolism. Many natural compounds from plant origin with anti-tumor attributes have been described.
Marta Rodríguez-Ruiz +8 more
doaj +1 more source
Neuroprotection and antioxidants
Neural Regeneration Research, 2016 Ischemia as a serious neurodegenerative disorder causes together with reperfusion injury many changes in nervous tissue. Most of the neuronal damage is caused by complex of biochemical reactions and substantial processes, such as protein agregation, reactions of free radicals, insufficient blood supply, glutamate excitotoxicity, and oxidative stress ...
Viera Danielisová, Maria Lalkovicova
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Polyfunctional hydrophilic antioxidants - from molecular design to practical application
Acta Biomedica Scientifica, 2016 The processes of lipid peroxidation are universal phenomena which to a greater or lesser degree always develops in membranous and lipoprotein complexes of living organisms.
N. V. Kandalintseva
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Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19? [PDF]
, 2020 Human lungs single cell RNA sequencing data from healthy donors (elderly and young; GEO accession number GSE122960) were analyzed to isolate and specifically study gene expression in alveolar type II cells.
Abouhashem, Ahmed S. +3 more
core +1 more source
Plant polyphenols as dietary antioxidants in human health and disease
Oxidative Medicine and Cellular Longevity, 2009 Polyphenols are secondary metabolites of plants and are generally involved in defense against ultraviolet radiation or aggression by pathogens. In the last decade, there has been much interest in the potential health benefits of dietary plant polyphenols
K. Pandey, S. Rizvi
semanticscholar +1 more source
Indian Journal of Endocrinology and Metabolism, 2012 Hyperglycemia promotes auto-oxidation of glucose to form free radicals. The generation of free radicals beyond the scavenging abilities of endogenous antioxidant defenses results in macro- and microvascular dysfunction. Antioxidants such as N-acetylcysteine, vitamin C and α-lipoic acid are effective in reducing diabetic complications, indicating that ...
Afreen Khan, Sarita Bajaj
openaire +4 more sources
Antioxidants, 2014 Polyphenols are natural products with recognized potential in drug discovery and development. We aimed to evaluate the polyphenolic profile of Araucaria angustifolia bracts, and their ability to scavenge reactive species.
Márcia O. Souza +6 more
doaj +1 more source
Trolox and ascorbic acid reduce direct and indirect oxidative stress in the IPEC-J2 cells, an in vitro model for the porcine gastrointestinal tract [PDF]
, 2015 Oxidative stress in the small intestinal epithelium is a major cause of barrier malfunction and failure to regenerate. This study presents a functional in vitro model using the porcine small intestinal epithelial cell line IPEC-J2 to examine the effects ...
De Smet, Stefaan +7 more
core +2 more sources
Neuroprotective Effect of Antioxidants in the Brain
International Journal of Molecular Sciences, 2020 The brain is vulnerable to excessive oxidative insults because of its abundant lipid content, high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) increase susceptibility to neuronal damage and functional deficits, via ...
K. Lee, M. Cha, B. Lee
semanticscholar +1 more source