Results 71 to 80 of about 948,009 (300)

The antioxidant action of taurine, hypotaurine and their metabolic precursors [PDF]

open access: yesBiochemical Journal, 1988
It has been suggested that taurine, hypotaurine and their metabolic precursors (cysteic acid, cysteamine and cysteinesulphinic acid) might act as antioxidants in vivo. The rates of their reactions with the biologically important oxidants hydroxyl radical (.OH), superoxide radical (O2.-), hydrogen peroxide (H2O2) and hypochlorous acid (HOCl) were ...
O I, Aruoma   +3 more
openaire   +2 more sources

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Stress response and tolerance mechanisms of spirobudiclofen exposure based on multiomics in Panonychus citri (Acari: Tetranychidae)

open access: yesiScience, 2023
Summary: The toxicity of insecticides used in the field decreases gradually to sublethal concentrations over time. Therefore, it is necessary to study sublethal effects of pesticides for controlling population explosion. Panonychus citri is a global pest
Hongyan Wang   +8 more
doaj   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Nitrogen Metabolism in Adaptation of Photosynthesis to Water Stress in Rice Grown under Different Nitrogen Levels

open access: yesFrontiers in Plant Science, 2017
To investigate the role of nitrogen (N) metabolism in the adaptation of photosynthesis to water stress in rice, a hydroponic experiment supplying with low N (0.72 mM), moderate N (2.86 mM), and high N (7.15 mM) followed by 150 g⋅L-1 PEG-6000 induced ...
Chu Zhong   +7 more
doaj   +1 more source

Selenium Transport Mechanism via Selenoprotein P—Its Physiological Role and Related Diseases

open access: yesFrontiers in Nutrition, 2021
Selenoprotein P (SELENOP) is selenium (Se)-containing protein in plasma, which is primarily produced in the liver. The “P” in SELENOP originated from the presence in plasma.
Yoshiro Saito
doaj   +1 more source

Antioxidative Metabolism in the Seedlings of Pigeonpea in Response to Lead and Cadmium Stress [PDF]

open access: yes, 2011
Effects of Pb and Cd stress on antioxidative systems were studied in pigeonpea (Cajanus cajan (L.) Millspaugh) cultivars T21 and LRG30. The seeds were grown under different concentrations of Pb and Cd for 8-days and activities of enzymes including ...
B. Priyadarshini, B. Sujatha* and
core  

Activity lipid peroxidation and glutathione systems of lymphocytes blood in patients with diffusive toxic struma

open access: yesБюллетень сибирской медицины, 2008
In this article results of research of some parameters of oxidizing metabolism in lymphocytes blood in patients with verified diffusive toxic struma (DTS) of a various degree of an expressiveness are represented.
O. I. Urazova   +6 more
doaj   +1 more source

Comparative transcriptome analysis revealed differential gene expression involved in wheat leaf senescence between stay-green and non-stay-green cultivars

open access: yesFrontiers in Plant Science, 2022
Breeders agree that leaf senescence is a favorable process for wheat seed yield improvement due to the remobilization of leaf nutrients. However, several studies have suggested that staying green may be an important strategy for further increasing wheat ...
Qing Li   +11 more
doaj   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

open access: yesAdvanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu   +12 more
wiley   +1 more source

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