Results 151 to 160 of about 5,494 (181)

Antiplasmodial Flavonoids fromErythrina sacleuxii

Planta Medica, 2006
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4'-methoxy-3'-prenylisoflavone ...
Andayi, Andrew W, Yenesew, Abiy, Derese, Solomon, Midiwo, Jacob O, Gitu, Peter M, Jondiko, Ogoche J I, Akala, Hosea, Liyala, Pamela, Wangui, Julia, Waters, Norman C, Heydenreich, Matthias, Peter, Martin G   +11 more
openaire   +3 more sources

Antitubercular and Antiplasmodial Constituents ofAbrus precatorius

Planta Medica, 2004
A known isoflavanquinone, abruquinone B ( 1), and a new derivative, abruquinone G ( 2), were isolated from the aerial parts of Abrus precatorius. Chemical structures of these compounds were elucidated by spectral analyses. While 1 exhibited antitubercular, antiplasmodial and cytotoxic activities, compound 2 showed mild antiviral and cytotoxic ...
Chutima, Limmatvapirat, Sinenart, Sirisopanaporn, Prasat, Kittakoop   +2 more
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Antiplasmodial Triterpene fromVernonia brasiliana

Planta Medica, 1997
The hexane extract from leaves of Vernonia brasiliana (L.) Druce (Compositae) was active in vitro against Plasmodium falciparum and in vivo in mice infected with Plasmodium berghei. This extract was subjected to a bioassay-guided fractionation protocol based on the in vitro model.
T M, Alves, T J, Nagem, L H, de Carvalho, A U, Krettli, C L, Zani   +4 more
openaire   +2 more sources

Identification and characterization of thiamine analogs with antiplasmodial activity

Antimicrobial Agents and Chemotherapy
ABSTRACT Thiamine is metabolized into thiamine pyrophosphate (TPP), an essential enzyme cofactor. Previous work has shown that oxythiamine, a thiamine analog, is metabolized by thiamine pyrophosphokinase (TPK) into oxythiamine pyrophosphate within the malaria parasite Plasmodium ...
Imam Fathoni, Terence C. S. Ho, Alex H. Y. Chan, Finian J. Leeper, Kai Matuschewski, Kevin J. Saliba   +5 more
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ANTIPLASMODIAL COMPOUNDS

2022
CHAKRABARTI DEBOPAM, CICHEWICZ ROBERT H, CAI SHENGXIN, LEE JIN WOO, COLLINS JENNIFER E   +4 more
openaire   +3 more sources

Harmicines as novel antiplasmodial leads

2019
Malaria, caused by the protozoal parasite Plasmodium, is a neglected tropical disease responsible for over 400000 deaths in 2017.1 The emergence of the multi-drug resistant Plasmodium strains has rendered the existing therapy ineffective. Harmine is an alkaloid of the -carboline type, with confirmed in vitro and in vivo antimalarial properties, while ...
Rajić, Zrinka, Perković, Ivana, Raic-Malic, Silvana, Marinovic, Marina, Poje, Goran, Prudencio, Miguel, Fontinha, Diana, Held, Jana   +6 more
openaire   +2 more sources

Antiplasmodial Activity

2018
Nubia Boechat, Luiz Carlos da Silva Pinheiro, Flavia Fernandes da Silveira   +2 more
openaire   +1 more source

Antiplasmodial activity of natural products

2022
Malaria är en potentiellt dödlig parasitsjukdom som överförs från myggor till människa och som orsakar återkommande episoder av hög feber. Parasiten har många olika stadier i sin livscykel, under ett av dessa stadier invaderar den röda blodkroppar i människan och det är detta stadie som ger symptom och som denna studie har fokuserat på.
openaire   +1 more source

Antiplasmodial Triterpenoids from the Fruits of Neem

Journal of Natural Products, 2010
Giuseppina Chianese, Serge R. Yerbanga, Leonardo Lucantoni, Annette Habluetzel, Nicoletta Basilico, Donatella Taramelli, Ernesto Fattorusso, Or   +7 more
openaire   +1 more source

Ceramicines B–D, new antiplasmodial limonoids from Chisocheton ceramicus

Bioorganic and Medicinal Chemistry, 2009
Khalijah Awang, Marc Litaudon
exaly