Results 81 to 90 of about 5,494 (181)

Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum

Journal of Cheminformatics
Drug discovery is an intricate and costly process. Repurposing existing drugs and active compounds offers a viable pathway to develop new therapies for various diseases.
Reagan M. Mogire, Silviane A. Miruka, Dennis W. Juma, Case W. McNamara, Ben Andagalu, Jeremy N. Burrows, Elodie Chenu, James Duffy, Bernhards R. Ogutu, Hoseah M. Akala   +9 more
doaj   +1 more source

<i>In Silico</i> Pharmacokinetic Profile and Antimalarial Efficacy of 3-Chloro-4-(4-Chlorophenoxy)Aniline. [PDF]

Biochem Res Int
Waithera MW, Kimani SK, Njoroge S, Nyahanga T, Kinyua JK.   +4 more
europepmc   +1 more source

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues. [PDF]

ACS Med Chem Lett
Elhalawaty EA, Alseedy HA, Woodland JG, Wicht KJ, Swart T, Rangel GW, Hoppe HC, Chibale K, Llinás M, Abadi AH, Ahmed NS.   +10 more
europepmc   +1 more source

Evaluation of Antiplasmodial Activity of Quinoline Derivatives Incorporating Arylnitro and Aminochalcone Moieties. [PDF]

Pharmaceuticals (Basel)
Ariefta NR, Beteck RM, Legoabe LJ, Nishikawa Y.   +3 more
europepmc   +1 more source

Isolation, purification and characterization of betulinic acid derivative from the root bark of <i>Afzelia africana</i> and its antiplasmodial and antimicrobial activities. [PDF]

Int J Biochem Mol Biol
Vigbedor BY, Osei Akoto C, Kwakye R, Osei-Owusu J, Ofosu-Koranteng F, Asante Donkor E, Hunkpe G, Kwashie P, Neglo D, Mawutor HC.   +9 more
europepmc   +1 more source

Novel Antiplasmodial Natural Products Identified Through a Modified Bioluminescence-Based Rate-of-Kill Assay. [PDF]

Biomedicines
Mobley R, Nasser SA, Bartholomew B, Nash R, Horrocks P, Price H.   +5 more
europepmc   +1 more source

Isolation and characterization of antiplasmodial and antimicrobial compounds from <i>Tetracera alnifolia</i> using a bioassay-guided approach. [PDF]

RSC Adv
Baldé MA, Traoré MS, Diallo MST, Matheeussen A, Aïssata C, Cos P, Maes L, Baldé AO, Camara MK, Balde AM, Tuenter E, Foubert K.   +11 more
europepmc   +1 more source

Antiplasmodial activity, phytochemical analysis and in silico study of the leaf extract of Chenopodium opulifolium Koch & Ziz used in Uganda. [PDF]

BMC Complement Med Ther
Saidi J, Namukobe J, Bunalema L, Chama MA, Dziwornu GA, Akala H, Amoah LE, Addotey JN.   +7 more
europepmc   +1 more source

Ruthenium Complexes of Atovaquone Acting on Multiple Stages of the <i>Plasmodium</i> Life Cycle. [PDF]

J Med Chem
Fabbri C, Marcon PHS, Santiago AS, Sousa CC, Quadros HC, de Sena Lamar Nunes L, de Menezes DDM, Santana RAG, Justiniano SCB, D'Alessandro S, Basilico N, Moreira DRM, de Araujo-Neto JH, Lopes SCP.   +13 more
europepmc   +1 more source

Evaluation of the Antimalarial Potential of a Combination of <i>Terminalia macroptera</i> and <i>Erythrina sigmoidea:</i> In Vitro and In Silico Assays. [PDF]

J Parasitol Res
Sandra TNJ, Nadia NAC, Cedric Y, Guy-Armand GN, Sidiki NNA, Azizi MA, Payne VK, Hu H.   +7 more
europepmc   +1 more source