Results 231 to 240 of about 186,437 (313)

CD8 T Cell Sensing of Type I Interferon Impacts Anergy

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Basal IFN‐I acts as a rheostat to fine‐tune CD8 T cell anergy. The presence of IFN‐I induces a less deep anergic state characterised by greater expansion, residual effector function and plasticity. This favours the accumulation of autoreactive T cells that retain the potential to break tolerance rather than undergoing deletion.
Anne S. Haefke, Hanna Gröber, Ioana Sandu, Vanessa Skipness, Nikos Pantouloufos, Fabienne Gräbnitz, Marie‐Elen Tuchel, Nathan Zangger, Dominique Stark, Marvin Kříž, Carmine Cristinzio, Hanspeter Pircher, Roman Spörri, Isaak Quast, Annette Oxenius   +14 more
wiley   +1 more source

Design and Synthesis of Marine Sarocladione Derivatives with Potential Anticancer Activity. [PDF]

Mar Drugs
Liu XM, Li WX, Kong LX, Han GY, Gui J, Li XW.   +5 more
europepmc   +1 more source

Noni (Morinda citrifolia L.) Fermented Juice Inhibits Tumor Progression of Breast Cancer Angiogenesis Through Suppressing NF‐κB Signaling

Food Frontiers, Volume 7, Issue 3, May 2026.
Noni fermented juice (NFJ) suppresses breast cancer progression by inhibiting angiogenesis via the Ikkβ/NF‐κB/VEGF pathway. This study demonstrates the potent antitumor effects of NFJ through the inhibition on the function of endothelial cells, identifying it as a safe therapeutic agent for breast cancer treatment. ABSTRACT Angiogenesis plays a crucial
Baijian Wu, Xiaoyu Xu, Zhihong Zhu, Yau‐Tuen Chan, Shaozhong Peng, Yanping Liu, Cheng Zhang, Ming Zhou, Xiaodan Huang, Yibin Feng   +9 more
wiley   +1 more source

Phytochemical compounds, antioxidant activity, and antiproliferative activity of sesame seeds as affected by simulated digestion. [PDF]

Food Chem X
Zhou L, Lin X, Guo R, Li T, Brennan C, Fu X, Liu RH.   +6 more
europepmc   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source

Jailed drug-coated balloon technique: an enhanced provisional approach to complex, non-left main bifurcations. [PDF]

AsiaIntervention
Khialani B, Jun Sim EW, Touma G, Ford T, Ada C, Karthikesan D, Wong B.   +6 more
europepmc   +1 more source

Saikosaponin A Inhibits Migration/Invasion and Triggers Cell‐Cycle Arrest and Autophagy‐Induced Cell Death in HCT116 Cells and In Vivo

Food Frontiers, Volume 7, Issue 3, May 2026.
Saikosaponin A from Radix Bupleuri inhibited colorectal cancer HCT116 cells with low toxicity. SSA induced S/G2‐M cell cycle arrest and triggered autophagy via mTOR inhibition. SSA suppressed metastasis by blocking PI3K/AKT signaling pathway. SSA significantly reduced tumor growth without apparent toxicity.
Xiu‐Xiu Zhang, Wang‐Wei Zhang, Run‐Hui Ma, Zhi‐Jing Ni, Kiran Thakur, Mohammad Rizwan Khan, Jian‐Guo Zhang, Zhao‐Jun Wei   +7 more
wiley   +1 more source

Synthesis and antitumor activity of mono and digold(i) alkynyl complexes with oligo(ethylene glycol)methylether. [PDF]

RSC Adv
Zeng Y, Zheng F, Jin L, Chen QM, Zhou P, Mou X, Wu XH, Zhang JF, Ren WX.   +8 more
europepmc   +1 more source

Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms

Food Frontiers, Volume 7, Issue 3, May 2026.
Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang, Han Chen, Jinping Si, Zhigang Han, Xinfeng Zhang   +4 more
wiley   +1 more source