Results 211 to 220 of about 120,892 (307)

Cryptocaryone Exhibits ROS/MAPK-Dependent Antiproliferative and Apoptosis-Inducing Effects on Triple-Negative Breast Cancer Cells and Proof-of-Concept Breast Cancer Mouse Model. [PDF]

Drug Dev Res
Chuang YT, Liu W, Chien TM, Farooqi AA, Chang HS, Shiau JP, Chang HW.   +6 more
europepmc   +1 more source

In vitro antiproliferative activity on A549 and HT-29 cell lines and fatty acid profiling of Agaricus bresadolanus and A. hortensis. [PDF]

Naturwissenschaften
Alli H, Demir İ, Yeniocak S, Kivrak İ, Sarac N, Kaya E, Ugur A.   +6 more
europepmc   +1 more source

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source

Design, Synthesis, and Biological Evaluation of Selective CDK4/9 Inhibitors. [PDF]

ACS Med Chem Lett
Li S, Yang X, Yin W, Zhang W, Li Z, Hu J, Li Y.   +6 more
europepmc   +1 more source

Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?

VIEW Medicine, Volume 1, Issue 1, August 2026.
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda, Tatsuya Watanabe, Satoshi Yuhara, John M. Kelly, Hirotsugu Kurobe, Toshiharu Shinoka   +5 more
wiley   +1 more source

Tetrazolylidene-Stabilized Gold(I) Complexes: Synthesis and Evaluation of Anticancer Activity <i>In Vitro</i>. [PDF]

Inorg Chem
Stifel S, Schmidt C, Richter LF, Pöthig A, Casini A, Kühn FE.   +5 more
europepmc   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, Volume 159, Issue 2, Page 460-466, 15 July 2026.
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Molecular Insights into the Interaction Between Metformin and Caffeine: The Time-Dependent Antagonism and Modulation of p53 Signaling in Cancer Cells. [PDF]

Molecules
Zeljković V, Bogavac M, Dekić M, Minić S, Mahmutović E, Kunkin V, Marković Z, Karaman M.   +7 more
europepmc   +1 more source

Phenylbenzothiazole Bis(Cyclometalated) Pt(IV) Complexes With Phenanthroline‐Based Ligands as ROS, NADH and Microtubule Destabilizing Agents

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
This study presents the optical and biological properties of the neutral and cationic phenylbenzothiazole cyclometalated Pt(IV) [Pt(pbt)2Cl2] (1) and [Pt(pbt)2(N^N)](ClO4)2 (N^N = phen 2, pyraphen 3, NH2‐phen 4) complexes. Complexes 1 and 4 demonstrated 1O2 generation and catalytic NADH photooxidation under blue light irradiation. The highest cytotoxic
Andrea Corral‐Zorzano, David Gómez de Segura, Icíar P. López, José G. Pichel, Elena Lalinde, M. Teresa Moreno   +5 more
wiley   +1 more source

The Tumor Cell Proliferation Inhibitory Activity of the Human Herpes Virus Type 6 U94 Protein Relies on a Stable Tridimensional Conformation. [PDF]

Microorganisms
Bertelli A, Uggeri M, Filippini F, Duheric M, Caccuri F, Caruso A.   +5 more
europepmc   +1 more source