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Immune-related adverse events are a potent predictor of post-transplant rejection in HCC: a multicentre retrospective cohort study. [PDF]

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Fang J, Zhong S, Wang T, He K, Mu A, Ong M, Lin Y, Zhu Z, Wang N, Wu J, Wang Z, Li Z, Gao F, Zhuang L, Guo Z, Zheng S, Li H, Zhang S, Ling Q.   +18 more
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Antiproliferatives and Transplantation

2021
Antiproliferative agents include Mycophenolic acid and Azathioprine (which is less commonly used unless in certain conditions). They were initially identified for use in autoimmune and cancer research due to their role in disruption of cellular replication.
Robert, Donovan, Howard, Eisen, Omaima, Ali   +2 more
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A Review on Acridines as Antiproliferative Agents

Mini-Reviews in Medicinal Chemistry, 2022
Abstract: Acridine derivatives have been thoroughly investigated and discovered to have multitarget qualities, inhibiting topoisomerase enzymes that regulate topological changes in DNA and interfering with DNA's vital biological function. This article discusses current progress in the realm of novel 9-substituted acridine heterocyclic compounds ...
Kalirajan Rajagopal, Aparna Baliwada, Potlapati Varakumar, Kannan Raman, Gowramma Byran   +4 more
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Antiproliferative properties of piperidinylchalcones

Bioorganic & Medicinal Chemistry, 2006
Methoxylated chalcones bearing N-methylpiperidinyl substituents on ring A inhibited the growth of human tumour cell lines (MCF, HCT 116, and Jurkat) at IC50 values of
Liu, X., Go, M.-L.
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New antiproliferative benzoindolinothiazepines derivatives

European Journal of Medicinal Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Guillaume, Laconde, Patrick, Depreux, Pascal, Berthelot, Nicole, Pommery, Jean-Pierre, Hénichart   +4 more
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Cardiotoxicity of the Antiproliferative Compound Fluorouracil

Drugs, 1999
The antimetabolite fluorouracil (5-FU) is frequently administered for chemotherapy of various malignant neoplasms. The drug is well known for its adverse effects involving bone marrow, skin, mucous membranes, intestinal tract and central nervous system, whereas its cardiotoxicity is less familiar to clinicians.
K, Becker, J F, Erckenbrecht, D, Häussinger, T, Frieling   +3 more
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Antiproliferative effects of peracetylated naphthoxylosides

Bioorganic & Medicinal Chemistry Letters, 2009
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs.
Ulrika, Nilsson, Mårten, Jacobsson, Richard, Johnsson, Katrin, Mani, Ulf, Ellervik   +4 more
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Synthesis and antiproliferative activity of retroetoposide

Bioorganic & Medicinal Chemistry Letters, 2003
Retro-4'-demethyl-4-epipodophyllotoxin 6 was synthesized in eight steps and 10% overall yield from 4'-demethyl-4-epipodophyllotoxin 12. Subsequent coupling of 22 with 1-O-trimethylsilyl-4,6-O-ethylidene-beta-D-glucoside 26 afforded retroetoposide 5 which is 10-fold less cytotoxic than etoposide against L1210 cell line.
Philippe, Meresse, Prokopios, Magiatis, Emmanuel, Bertounesque, Claude, Monneret   +3 more
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THE ANTIPROLIFERATIVE ASPECTS OF MORTALIN (REVIEW)

International Journal of Oncology, 1995
Cellular mortal and immortal phenotypes as defined by the limited and the infinite capacity of cells to divide are the characteristics of normal and cancerous cells in culture. Numerous strategies that have been employed to understand the mechanism(s) of normal as well as tumor cell growth have revealed that these are genetically controlled, however ...
R, Wadhwa, Y, Mitsui, T, Ide, S, Kaul
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