Results 201 to 210 of about 186,437 (313)

Evaluation of Enzyme Inhibition and Kinetic Profiles of Origanum Essential Oils on Metabolic and Central Nervous System Targets

Natural Sciences, Volume 6, Issue 3, July 2026.
The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato, Lucia Caputo, Laura De Martino, Daniela Grulova, Barbara Borczak, Joanna Kapusta‐Duch, Vincenzo De Feo   +6 more
wiley   +1 more source

Euphorbia bicolor Xylene Extract Induces Mitochondrial and Endoplasmic Reticulum Stress-Mediated Apoptotic Pathways in MDA-MB-231 and T47D Cells. [PDF]

Int J Mol Sci
Rumpa MM, Ngo NL, Maier C.
europepmc   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

Biological Reviews, Volume 101, Issue 3, Page 1582-1605, June 2026.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola, David Brankovits, Tiziana Di Lorenzo, Isabel R. Amorim, Raluca Ioana Bancila, Adrià Bellvert, Enrico Bernard, Anna Blomberg, Paulo A.V. Borges, Martina Cappelletti, Rodrigo Lopes Ferreira, Rosalina Gabriel, Diana M. P. Galassi, Laura Garzoli, Vasilis Gerovasileiou, Grant C. Hose, Kathryn L. Korbel, Simone Martino, Ana Z Miller, Nataša Mori, Veronica Nanni, Giuseppe Nicolosi, Mattia Saccò, Troy S. Sakihara, Marconi Souza Silva, Anne E. Tamalavage, Maja Zagmajster, Efraín Chávez, Christian Griebler, Pedro Cardoso, Alejandro Martínez   +30 more
wiley   +1 more source

Discovery of natural apigenin analogues as lysine-specific demethylase 1 inhibitors against tumoral testicular germ cells. [PDF]

Sci Rep
Sun LW, Zhang M, Li CF, Wang C, Li Y.
europepmc   +1 more source

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

3D-QSAR study for the development of chalcone-based inhibitors targeting ovarian cancer cells with experimental validation. [PDF]

Front Pharmacol
Valenzuela-Valderrama M, Varas A, Rubilar M, Lorca M, Mella J, Espinosa-Bustos C, Mellado M, Echeverría J.   +7 more
europepmc   +1 more source

Edulitin 2, a Ribotoxin‐Like Protein From Boletus edulis That Triggers Apoptosis in Colon Cancer Cells While Preserving the Integrity of the Intestinal Microbiota

eFood, Volume 7, Issue 3, June 2026.
Edulitin 2 is a ribotoxin‐like protein exhibiting a potent antiproliferative activity towards Caco‐2 and HT29 cells by programmed cell death. However, edulitin 2 does not affect gut microbiota growth, despite damaging fungal ribosomes. ABSTRACT Porcini (Boletus edulis Bull.) are a reservoir of pharmacological biomolecules with health‐promoting ...
Massimo Bortolotti, Sara Ragucci, Federica Falà, Anella Saggese, Francesco Biscotti, Ylenia De Luca, Nicola Landi, Paolo V. Pedone, Andrea Bolognesi, Ezio Ricca, Letizia Polito, Antimo Di Maro   +11 more
wiley   +1 more source

Corrigendum to 'Superior Antiproliferative and Enhanced Synergistic Effects of a Rock Inhibitor in Multiple Models for Keloid Disease' JID Innovations, Volume 5, Issue 6, November 2025, 100402. [PDF]

JID Innov
Ghasemishahrestani Z, Wilgus TA, Khumalo NP, Bayat A.   +3 more
europepmc   +1 more source

Induction of Apoptosis in MCF‐7 Breast Cancer Cells by Selenium Nanoparticles Synthesized With Laccase Enzyme Isolated From Pleurotus Floridanus

eFood, Volume 7, Issue 3, June 2026.
This study showed the first successful synthesis of selenium nanoparticles (SeNPs) using laccase purified from Pleurotus floridanus, offering an eco‐friendly and biocompatible replacement to conventional chemical methods. The biosynthesized SeNPs exhibited significant antiproliferative effects on MCF‐7 breast cancer cells, with cell cycle analysis ...
Shenbhagaraman Ramalingam, Arthi Karunanithi, Ammar B. Altemimi, Jenefar Sudarson, Sakthivel Muthu, Kodiganti Naresh Kumar, Rawaa H. Tlay, Tarek Gamal Abedelmaksoud   +7 more
wiley   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source