Results 251 to 260 of about 5,874,294 (289)
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Synthesis and antiproliferative activity of 6-naphthylpterocarpans
Organic & Biomolecular Chemistry, 2020The Heck-oxyarylation of 2 H -chromenes afforded (6 S *,6a R *,11a R *)-6-naphthylpterocarpans with potent antiproliferative activity.
Ádám Szappanos +7 more
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Antioxidant and antiproliferative activity of curcumin semicarbazone
Bioorganic & Medicinal Chemistry Letters, 2005A new semicarbazone derivative of curcumin (CRSC) was synthesized and examined for its antioxidant, antiproliferative, and antiradical activity and compared with those of curcumin (CR). The antioxidant activity was tested by their ability to inhibit radiation induced lipid peroxidation in rat liver microsomes.
Sabari, Dutta +3 more
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Antiproliferative activity of chalcones with basic functionalities
Bioorganic & Medicinal Chemistry, 2007A library of chalcones with different basic groups were synthesized and evaluated for antiproliferative activities against the human breast cancer (MCF 7) and colon cancer (HCT 116) cell lines. Structure-activity relationships were analyzed by projection methods (PCA/PLS) and multiple linear regression.
Liu, X., Go, M.-L.
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Synthesis and antiproliferative activity of novel methylselenocarbamates
European Journal of Medicinal Chemistry, 2014A series of new aliphatic, aromatic and heteroaromatic carbamate derivatives containing a methylseleno moiety were synthesized and evaluated in vitro for their cytotoxic activity against a panel of human cell lines including CCRF-CEM (lymphoblastic leukaemia), K-562 (lymphocytic leukaemia), HT-29 (colon carcinoma), HTB-54 (lung carcinoma), PC-3 ...
Beatriz Romano +4 more
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Marine Natural Meroterpenes: Synthesis and Antiproliferative Activity [PDF]
Marine Drugs, 2010 Meroterpenes are compounds of mixed biogenesis, isolated from plants, microorganisms and marine invertebrates. We have previously isolated and determined the structure for a series of meroterpenes extracted from the ascidian Aplidium aff. densum. Here, we demonstrate the chemical synthesis of three of them and their derivatives, and evaluate their ...
Laurent Soulère +2 more
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Antiproliferative and Cytotoxic Activities
2018Cancer is a genetic disease, affecting many people worldwide. Chemotherapy is routinely used for cancer treatment. However, this therapeutic approach is not always effective due to the development of cell resistance and toxic effects. Plants are a reservoir of natural chemicals with chemoprotective potential against cancer and with low adverse effects.
Anesini, Claudia Alejandra +2 more
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Antiproliferative Activity of Cobra Venom Cytotoxins
Current Topics in Medicinal Chemistry, 2015Cytotoxins (or cardiotoxins, CTs) are small rigid membrane-active proteins of the three-finger toxin (TFT) family. They comprise about 60 amino acid residues, stabilized by four disulphide bridges. CTs, the most abundant proteins in cobra venom are able to kill cancer cells in a dose and time-dependent manner.
Peter V, Dubovskii, Yuri N, Utkin
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Antiangiogenic and antiproliferative activity of suramin analogues
Cancer Chemotherapy and Pharmacology, 1997The purpose of this study was to test the ability of 70 polyanionic analogues of suramin to inhibit angiogenesis. The ID50, the dose that produced 50% inhibition of angiogenesis, was determined for suramin and each of the analogues by measuring the ability of various amounts to inhibit angiogenesis in vivo in the chick egg chorioallantoic membrane (CAM)
A R, Gagliardi +5 more
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Anticancer and antiproliferative activity of natural brassinosteroids
Phytochemistry, 2008Brassinosteroids (BRs) are steroid plant hormones that are essential for many plant growth and developmental processes, including cell expansion, vascular differentiation and stress responses. Up to now the inhibitory effects of BRs on cell division of mammalian cells are unknown.
Jana, Malíková +3 more
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Fungal Proteins with Antiproliferative and Anticancer Activities
Protein & Peptide Letters, 2013Fungi produce a variety of proteins with antiproliferative activity toward tumor cells and anticancer activity in tumor bearing mice. The aforementioned fungal proteins include ribonucleases, antifungal proteins, ubiquitin-like peptides, ribosome inactivating proteins, hemolysins, hemagglutinins/lectins, laccases, and protein-bound polysaccharopeptides.
T B, Ng, J H, Wong
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