Results 251 to 260 of about 155,512 (310)

The Structure-Antiproliferative Activity Relationship of Pyridine Derivatives. [PDF]

Int J Mol Sci
Villa-Reyna AL, Perez-Velazquez M, González-Félix ML, Gálvez-Ruiz JC, Gonzalez-Mosquera DM, Valencia D, Ballesteros-Monreal MG, Aguilar-Martínez M, Leyva-Peralta MA.   +8 more
europepmc   +1 more source

Intestinal Organoid‐Based Mathematical Modeling Predicts Clinical Gastrointestinal Toxicity of Oral Oncology Drugs

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Gastrointestinal (GI) toxicity is a common and potentially severe side effect of antiproliferative cancer therapies that often requires dose reduction or treatment interruption. Despite the clinical implications, there are currently no robust strategies for quantitative preclinical assessment of GI toxicity.
Carmen Pin, Deepa Maheshvare M., Louis Gall, Andrew Hall, Muireann Coen, Ambra Bianco, Shimeng Liu, Kenneth Pryde   +7 more
wiley   +1 more source

Antioxidant, Anti-Inflammatory, and Antiproliferative Activity of a Callus Culture of <i>Prionosciadium dissectum</i> (Apiaceae). [PDF]

Plants (Basel)
Bernabé-Antonio A, Sánchez-Carranza JN, Silva-Guzmán JA, Romero-Estrada A, Pérez-Rodríguez SG, Cruz-Sosa F, Sánchez-Ramos M, Nieto-Trujillo A.   +7 more
europepmc   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Design, synthesis, <i>in silico</i> studies, and antiproliferative activity of a novel series of thiazole/1,2,3-triazole hybrids as apoptosis inducers and multi-kinase inhibitors endowed with anti-breast cancer activity. [PDF]

RSC Adv
Mohamed FAM, Alakilli SYM, Alhassan HH, Yousif SO, Alatwi E, Gomaa HAM, Alrub HA, Alyami BA, Abdelhafez AH, Bräse S, Youssif BGM.   +10 more
europepmc   +1 more source

Design, synthesis and antiproliferative activity of novel colchicine derivatives: selective inhibition of melanoma cell proliferation. [PDF]

Front Pharmacol
Kumar P, Kotra T, Lone WI, Arfath Y, Tiwari H, Shukla AK, Ahmed Z, Rayees S, Anal JMH.   +8 more
europepmc   +1 more source

Design, synthesis, and <i>in silico</i> studies of new benzofuran-pyrazole hybrids as multi-kinase inhibitors with potential antiproliferative activity. [PDF]

RSC Adv
Abd El-Karim SS, Syam YM, Abdelkader RM, El-Ashrey MK, Anwar MM.   +4 more
europepmc   +1 more source

Piperazine-Substituted Pyranopyridines Exhibit Antiproliferative Activity and Act as Inhibitors of HBV Virion Production. [PDF]

Int J Mol Sci
Buloyan S, Harutyunyan A, Gasparyan H, Sakeyan A, Shahkhatuni A, Zakirova NF, Yusubalieva G, Kirillov IM, Fedyakina IT, Solyev PN, Lipatova AV, Bogomolov MA, Prassolov VS, Lebedev TD, Ivanov AV.   +14 more
europepmc   +1 more source

Design, synthesis, and SAR of antiproliferative activity of trioxatriangulene derivatives. [PDF]

RSC Med Chem
Naiya MM, Guan IA, Sullivan M, Eurtivong C, Leung E, Pilkington LI, Barker D.   +6 more
europepmc   +1 more source

Design, synthesis, and apoptotic antiproliferative activity of novel dihydropyrimidine-5-carbonitrile/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors endowed with antioxidant activity. [PDF]

RSC Adv
Al-Wahaibi LH, Mohamed AM, Abou-Zied HA, Abdullah Alzahrani AY, Bräse S, Youssif BGM.   +5 more
europepmc   +1 more source