Results 241 to 250 of about 5,874,294 (289)

Design, synthesis and antiproliferative activity of oxadiazole derivatives as potent glycogen synthase kinase-3/histone deacetylase 6 dual inhibitors. [PDF]

J Enzyme Inhib Med Chem
Ye C, Chen Z, Jiang J, Li J, Kong R, Liu S, Chen X, Xu Z.   +7 more
europepmc   +1 more source

Phytochemical study of <i>Homalanthus giganteus</i>: isolation, antiproliferative activity, and computational mechanistic insights of tigliane diterpenes against colorectal cancer. [PDF]

Pharm Biol
Wirasisya DG, Kincses A, Setiawansyah A, Barta A, Chang FR, Hohmann J.   +5 more
europepmc   +1 more source

Design, Synthesis and Antiproliferative Activity Studies of Novel 1,2,3-Triazole-Urea Hybrids. [PDF]

Drug Des Devel Ther
Gao E, Zhang H, Guo Y, Wang X, Mao L, Peng L, Xu G, Yao X, Li S, Long H, Wang T, Wu H.   +11 more
europepmc   +1 more source

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Synthesis and antiproliferative activity of retroetoposide

Bioorganic & Medicinal Chemistry Letters, 2003
Retro-4'-demethyl-4-epipodophyllotoxin 6 was synthesized in eight steps and 10% overall yield from 4'-demethyl-4-epipodophyllotoxin 12. Subsequent coupling of 22 with 1-O-trimethylsilyl-4,6-O-ethylidene-beta-D-glucoside 26 afforded retroetoposide 5 which is 10-fold less cytotoxic than etoposide against L1210 cell line.
Philippe, Meresse, Prokopios, Magiatis, Emmanuel, Bertounesque, Claude, Monneret   +3 more
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Antioxidant and Antiproliferative Activities of Strawberries

Journal of Agricultural and Food Chemistry, 2003
Strawberries contain high levels of antioxidants, which have been correlated with a decreased risk of chronic disease. To more fully characterize the antioxidant profiles and possible associated health benefits of this fruit, the total free and bound phenolic, total flavonoid, and total anthocyanin contents of eight strawberry cultivars (Earliglow ...
Katherine J, Meyers, Christopher B, Watkins, Marvin P, Pritts, Rui Hai, Liu   +3 more
openaire   +2 more sources

Synthesis and antiproliferative activity of alkylphosphocholines

Chemistry and Physics of Lipids, 2003
Alkylphosphocholines (APC) with one or more methylene groups in the alkyl chain replaced by oxygen atoms or carbonyl groups, or both have been assembled modularly using omega-diols as central building blocks. Out of 25 new compounds of this kind, 11 were evaluated for their antiproliferative activity on four cell lines and compared with miltefosine to ...
M. AGRESTA, D'ARRIGO, PAOLA, FASOLI, EZIO, D. LOSI, G. PEDROCCHI FANTONI, S. RIVA, SERVI, STEFANO, TESSARO, DAVIDE   +7 more
openaire   +5 more sources

Antioxidant and Antiproliferative Activities of Raspberries

Journal of Agricultural and Food Chemistry, 2002
Raspberries are rich in phenolic phytochemicals. To study the health benefits of raspberries, four fresh raspberry varieties (Heritage, Kiwigold, Goldie, and Anne) were evaluated for total antioxidant and antiproliferative activities. The total amount of phenolics and flavonoids for each of the four raspberry varieties was determined.
Ming, Liu, Xin Qi, Li, Courtney, Weber, Chang Yong, Lee, Janice, Brown, Rui Hai, Liu   +5 more
openaire   +2 more sources

Antiproliferative activity of the Netherlands propolis and its active principles in cancer cell lines

Journal of Ethnopharmacology, 2002
The MeOH extract of the Netherlands propolis showed promising antiproliferative activity toward highly liver-metastatic murine colon 26-L5 carcinoma with an EC50 value of 3.5 \u3bcg/ml.
Suresh Awale, Arjun H Banskota
exaly   +2 more sources

Constituents of Chinese Propolis and Their Antiproliferative Activities

Journal of Natural Products, 2002
Two new flavonoids, 3-O-[(S)-2-methylbutyroyl]pinobanksin (1) and 6-cinnamylchrysin (2), were isolated from the EtOAc-soluble fraction of the MeOH extract of Chinese propolis, along with 12 known compounds (3-14). The structures of the isolated compounds were elucidated on the basis of spectroscopic and chemical analyses.
Usia, Tepy, Banskota, Arjun H., Tezuka, Yasuhiro, Midorikawa, Kiyoshi, Matsushige, Katsumichi, Kadota, Shigetoshi   +5 more
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Antioxidant and Antiproliferative Activities of Common Fruits

Journal of Agricultural and Food Chemistry, 2002
Consumption of fruits and vegetables has been associated with reduced risk of chronic diseases such as cardiovascular disease and cancer. Phytochemicals, especially phenolics, in fruits and vegetables are suggested to be the major bioactive compounds for the health benefits.
Jie, Sun, Yi-Fang, Chu, Xianzhong, Wu, Rui Hai, Liu   +3 more
openaire   +2 more sources